Test Price
1,800 AED✅ Home Collection Available
Hepatitis B Viral Drug Resistance & Genotyping Test in UAE | 1800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Clinical Assurance – UAE Trusted Diagnostics
- High Diagnostic Accuracy – NGS sequencing on Illumina platform, validated against international proficiency panels and DHA quality standards.
- VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – DHA‑licensed phlebotomists with ISO‑certified cold‑chain logistics (2–8°C). Same‑day collection available daily from 8 AM to 11 PM.
- Post‑Test Clinical Guidance – Complimentary 15‑minute tele‑consultation with a Consultant Medical Genetics to interpret your genotypic resistance profile.
- Direct Insurance Billing – WhatsApp +971 54 548 8731 for real‑time coverage verification and pre‑authorisation.
Test Overview & Methodology
The Hepatitis B Viral Drug Resistance & Genotyping test uses next‑generation sequencing (NGS) to identify HBV genotypes (A–J) and detect resistance mutations to antivirals such as lamivudine, adefovir, entecavir, and tenofovir, critical for tailoring therapy in chronic hepatitis B. This advanced molecular assay examines the full reverse transcriptase region to capture both common and low‑frequency resistance variants.
| Feature | Our Test – NGS Comprehensive Panel | Standard Genotyping Only |
|---|---|---|
| Methodology | NGS (Illumina platform) – full reverse transcriptase region | Sanger sequencing (limited to partial genome) |
| Drug Resistance Genes Covered | rtA194T, rtL180M, rtM204V/I, and all clinically relevant variants | May miss low‑frequency variants; only genotype |
| Turnaround Time | 7 days (sample accepted daily until 11 AM) | 10–14 days |
| UAE Regulatory | DHA/MOHAP approved, ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Variable accreditation |
Physician Insight & Safety Protocols
“As a DHA‑licensed Consultant Medical Genetics (Registration ID: 9294403), I emphasise that HBV genotyping and resistance testing is not a screening tool. It must be interpreted alongside HBV DNA levels, liver enzymes, and clinical history. A negative resistance report does not exclude poor compliance or evolving viral quasispecies. Never alter treatment without consulting your hepatologist.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics
Advisory Precautions
- Do not discontinue prescribed antiviral medication without explicit instruction from your treating physician; abrupt cessation can cause severe hepatitis flare.
- This test requires a plasma level ≥3 mL collected in 2 Lavender Top (EDTA) tubes, separated aseptically within 2 hours and shipped refrigerated or frozen. Improper handling leads to sample rejection.
Exclusion Criteria & Emergency Indicators
- Exclusion criteria: Patients with decompensated cirrhosis, active hepatic encephalopathy, or those on direct‑acting anticoagulants (DOACs) with INR >2.5 must be stabilised in a supervised setting before elective phlebotomy.
- ER red flags: Sudden onset of jaundice, ascites, confusion, or haematemesis require immediate emergency care – call 998 for UAE ambulance. Home collection is not a substitute for emergency evaluation.
Patient FAQ & Clinical Guidance
1. Who should order the Hepatitis B Drug Resistance & Genotyping test?
This advanced molecular test is prescribed for adults on long‑term oral antiviral therapy who exhibit virological breakthrough (persistent HBV DNA >2000 IU/mL after initial suppression) or for treatment‑naïve patients with known high‑risk exposures to determine genotype‑specific therapy selection.
2. What does the result report include?
Results detail the HBV genotype (e.g., A, D, E), list any detected drug resistance mutations with ClinVar annotations, and provide an interpretive guide aligning with current EASL/AASLD treatment guidelines, helping your physician select the most effective antiviral regimen.
3. Is any special preparation required before the blood draw?
No fasting or dietary restrictions are needed; however, inform the home collection team about all current medications and recent immunisations. A certified phlebotomist will collect 3 mL of plasma in a cold‑chain ready kit, and you may resume normal activities immediately.
UAE Regulatory & Data Privacy Adherence
This diagnostic service operates in full compliance with UAE federal data protection and health information governance frameworks:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – governing the collection, processing, and storage of personal health data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – regulating digital health records and telemedicine consultations.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – ensuring patient safety and clinical accountability throughout the diagnostic pathway.
All laboratory processes are ISO 9001:2015 certified, and results are transmitted via encrypted channels. Patient consent is obtained prior to sample collection in accordance with DHA standards.
Clinical & Logistical Metadata
| Test Name | Hepatitis B Viral Drug Resistance & Genotyping |
| Price (AED) | 1,800 |
| Turnaround Time | 7 days |
| Sample Type / Matrix | Plasma (3 mL, Lavender Top EDTA tubes) |
| Methodology Used | Next‑Generation Sequencing (NGS) – Illumina platform, full reverse transcriptase region |
| ICD-10-CM Code | B18.1 |
| LOINC Code | 42719-3 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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