Test Price
800 AED✅ Home Collection Available
HbE (Hemoglobin E) Mutation Screening (Prenatal) in UAE | 800 AED | DHA-Licensed Laboratory
Executive Summary & Core Metrics
Clinical Confidence
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Endpoint PCR Processing
- Exact LOINC 31208-2 alignment, ensuring DHA-mandated interoperability
Logistics & Support
- Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Results available in 3-4 Days
- Telephonic Post-Test Clinical Guidance on result interpretation
Test Overview & Methodology
This prenatal test detects the hemoglobin E (HbE) mutation in fetal DNA using highly sensitive Endpoint PCR, enabling early risk assessment for hemoglobinopathies. The assay analyzes fetal material obtained from chorionic villus sampling (CVS), amniocentesis, or cordocentesis, providing precise molecular identification without maternal cell contamination.
| Feature | Our Test (Authorized DHA Lab) | Closest Alternative (General Lab) |
|---|---|---|
| Methodology | Endpoint PCR with Sequence Confirmation | Electrophoresis alone (lower sensitivity) |
| Turnaround Time | 3-4 Days (Guaranteed) | 5-7 Days (Variable) |
| Collection Method | Hospital-Only Invasive Procedure (CVS/Amniocentesis/Cordocentesis) | Non-invasive blood-based screening only (limited sensitivity for HbE) |
| Post-Test Guidance | Included Telephonic Clinical Consult | None or Report Only |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
"Prenatal HbE mutation screening provides critical information for families at risk of hemoglobinopathies. This molecular test should be integrated with comprehensive genetic counseling to ensure parents understand the implications of carrier status or affected pregnancies. Our validated Endpoint PCR method delivers high accuracy, but results must be interpreted in the context of parental carrier screening and family history. Every case benefits from a multidisciplinary approach involving obstetricians, geneticists, and neonatologists."
Exclusion Criteria & Emergency Red Flags
- Absolute Contraindications for Invasive Sampling: Active vaginal bleeding, placental abruption suspicion, or recent cervical cerclage placement.
- Relative Contraindications: Uncontrolled maternal diabetes, severe hypertension, or infections (e.g., HIV with high viral load) – discuss with your obstetrician.
- Immediate Post-Procedure ER Alerts: Heavy bleeding, persistent abdominal cramping, fever, or amniotic fluid leakage require emergency evaluation.
- Genetic Counseling Prerequisite: This test is most beneficial when accompanied by pre- and post-test genetic counseling, particularly for couples with known carrier status.
Patient FAQ & Clinical Guidance
1. How accurate is the HbE mutation screening during pregnancy?
Our Endpoint PCR assay detects the HbE mutation with 99.9% diagnostic sensitivity, meaning false results are virtually eliminated when combined with clinical assessment. The test analyzes fetal DNA from chorionic villi, amniotic fluid, or cord blood, ensuring robust molecular identification without maternal cell contamination.
2. Do I need a prescription to undergo this prenatal genetic test?
Yes, a doctor’s prescription from a gynecologist or clinical geneticist is mandatory to perform this prenatal test. This requirement safeguards proper clinical follow-up and accurate interpretation of results by a qualified specialist.
3. Can I use insurance and how do I arrange the hospital procedure?
We accept most UAE private medical insurance plans; verify your coverage instantly by sending your policy details via WhatsApp to +971545488731 for direct billing approval. The sample collection is performed exclusively within accredited hospital facilities during an invasive procedure (CVS, amniocentesis, or cordocentesis) scheduled by your obstetrician. No home collection is available for this test.
UAE Regulatory & Data Privacy Adherence
Your genetic data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | HbE (Hemoglobin E) Mutation Screening (Prenatal) |
| Price (AED) | 800 |
| Turnaround Time | 3-4 Days |
| Sample Type / Matrix | Fetal DNA (Chorionic Villus, Amniotic Fluid, or Cord Blood) |
| Methodology Used | Endpoint PCR with Sequence Confirmation |
| ICD-10-CM Code | Z31.5, O36.8 |
| LOINC Code | 31208-2 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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