Test Price
1,000 AED✅ Home Collection Available
Alpha Thalassemia Mutation Screening (3 Common Mutations) in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic post-test clinical guidance in result interpretation by a qualified genetic counsellor.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731 (pre-authorisation required before test).
- Price: 1,000 AED — comprehensive targeted mutation analysis with definitive carrier and disease status determination.
Test Overview & Methodology
This targeted genetic test identifies the three most prevalent deletional and non-deletional mutations in the HBA1 and HBA2 genes responsible for alpha-thalassemia, enabling precise carrier screening and diagnosis. Using End Point PCR with LC-MS/MS validated amplification, the assay provides definitive genotyping for the most common alpha-globin variants encountered in the UAE population.
Why Our Test Outperforms Standard Alternatives
| Feature | Our Test – End Point PCR (3 Common Mutations) | Hb Electrophoresis / HPLC |
|---|---|---|
| Methodology | Targeted DNA amplification (LC-MS/MS validated) | Hemoglobin fraction quantification |
| Mutations Detected | Three common alpha-thal mutations (deletional and non-deletional) | No direct mutation identification |
| Diagnostic Sensitivity | Greater than 99% for targeted variants | Indeterminate; often normal in alpha-thal trait |
| Turnaround Time | 7–8 working days | 2–3 days |
| Sample Required | Peripheral blood (2 mL EDTA) | Whole blood (same tube) |
| Clinical Utility | Definitive carrier/disease status, genetic counselling | Supportive but cannot rule out alpha-thalassemia |
| Price (AED) | 1,000 | ~300–500 (limited information) |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403: “Receiving a genetic screening result for alpha-thalassemia can provide clarity for your health and family planning decisions. Our targeted three-mutation panel covers the most clinically significant variants in the UAE population. I always emphasise that a positive finding must be interpreted alongside your full blood count, iron studies, and personal medical history. Our genetics team is committed to supporting you with compassionate post-test counselling and a clear, individualised care pathway.”
Advisory & Medication Guidance
Do not discontinue prescribed medication without consulting your doctor. Always inform your healthcare provider about any supplements or treatments you are taking prior to sample collection.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion criteria for venipuncture: Active fever or acute infection, severe anaemia (Hb less than 7 g/dL requiring urgent transfusion), uncorrected coagulopathy (INR greater than 1.5), and lack of informed consent (legal guardian required for minors per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Paediatric and neonatal cases: A paediatric phlebotomist must be arranged; sample volume adjusted accordingly.
- Emergency red flags – seek immediate medical attention: Sudden pallor, jaundice, rapid abdominal swelling suggestive of splenic sequestration, shortness of breath, or fainting.
Patient FAQ & Clinical Guidance
1. What does this test detect?
This test detects the three most common alpha-globin gene deletions and point mutations responsible for alpha-thalassemia carrier status and disease. It provides definitive genetic information for reproductive counselling and clinical diagnosis.
2. How is the sample collected?
A peripheral blood sample is drawn via simple venipuncture by a DHA-licensed phlebotomist, either at our facility or through our VIP Mobile Phlebotomy and Temperature-Controlled Cold-Chain Home Collection service. No fasting is required.
3. What do the results mean?
A positive result indicates carrier or disease status for one of the three tested alpha-globin mutations, while a negative result significantly reduces the likelihood but does not exclude rare alpha-thalassemia variants not covered by this panel.
4. Is genetic counselling provided after the test?
Yes, every patient receives telephonic post-test clinical guidance from a qualified genetic counsellor to help interpret the results and discuss implications for family planning and health management.
5. How long does it take to receive results?
The turnaround time is 7–8 working days from sample collection at the laboratory.
UAE Regulatory & Data Privacy Adherence
All procedures at DNA Labs UAE comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Genetic testing on minors follows the consent requirements of Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic data remains strictly confidential and is processed under ISO 9001:2015 accredited protocols.
Clinical & Logistical Metadata
| Test Name | Alpha Thalassemia Mutation Screening (3 Common Mutations) |
| Price (AED) | 1,000 |
| Turnaround Time | 7–8 Working Days |
| Sample Type / Matrix | Peripheral Whole Blood (2 mL EDTA) |
| Methodology Used | End Point PCR (Targeted DNA Amplification with LC-MS/MS Validation) |
| ICD-10-CM Code | D56.0 |
| LOINC Code | 49273-9 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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