Test Price
2,800 AED✅ Home Collection Available
OPTN Gene Glaucoma (Open-Angle Type 1E) – Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This targeted Next-Generation Sequencing (NGS) test analyzes the entire coding region of the OPTN gene, the key gene associated with hereditary open-angle glaucoma type 1E. Early detection empowers personalized surveillance and management, reducing irreversible vision loss.
| Feature | Our Test (OPTN NGS) | Standard Clinical Exam Only |
|---|---|---|
| Precision | 99.9% variant detection with CNV analysis | No genetic data |
| Method | NGS (Illumina platform) – full gene coverage | Slit-lamp exam, IOP measurement |
| Turnaround | 3 to 4 weeks for definitive molecular result | Immediate clinical findings, no genetic risk stratification |
| Clinical Utility | Guides personalized therapy, family cascade screening | Does not assess hereditary risk |
Physician Insight & Safety Protocols
"As your DHA-licensed Consultant Medical Geneticist (DHA: 9294403), I recognize that genetic testing for glaucoma can provoke uncertainty. This OPTN gene analysis delivers critical information, yet it must be correlated with your complete ophthalmic examination. Always review your results with a qualified specialist to understand the implications."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics
Clinical Advisory
⚠ Important: Do not discontinue any prescribed glaucoma medication without consulting your treating ophthalmologist. Genetic test results are not a substitute for ongoing clinical management.
Exclusion Criteria & Emergency Red Flags
- Minors (under 18) without court-appointed guardian consent or legal authorization per UAE regulations.
- Individuals unable to provide valid informed consent.
- Active high fever (>38.5°C) or acute systemic infection; postpone blood collection until resolved.
- Severe bleeding tendency or current anticoagulant therapy at risk for uncontrolled bleeding – consult your physician.
🚨 Emergency Red Flags:
If you experience sudden severe eye pain, nausea, vomiting, blurred vision, or halos around lights after the blood draw, seek immediate emergency medical attention. These symptoms may indicate acute angle-closure glaucoma, an unrelated but serious condition.
Patient FAQ & Clinical Guidance
1. What is the OPTN gene and its role in open-angle glaucoma type 1E?
Mutations in the OPTN gene impair cellular waste clearance, triggering inherited open-angle glaucoma type 1E. The OPTN gene provides instructions for optineurin, which regulates autophagy and intraocular pressure. Pathogenic variants cause early-onset open-angle glaucoma, often with severe progression. Identifying the mutation enables targeted monitoring and family cascade testing.
2. How is the test performed and what sample is required?
A blood sample is sequenced with NGS to analyze the entire OPTN gene for variants. We collect 3–5 mL of whole blood in an EDTA tube or a drop on an FTA card via our VIP Mobile Phlebotomy service. DNA is extracted and subjected to high-coverage Next-Generation Sequencing covering all exons and splice sites. Results are interpreted by clinical geneticists and reported in 3–4 weeks.
3. Is this genetic test covered by UAE health insurance?
Direct billing verification via WhatsApp; many UAE insurers cover this genetic glaucoma test with pre-authorization. We facilitate instant insurance eligibility checks through our partnership with major networks. A physician referral and prior authorization may be required. Contact our support team on +971 54 548 8731 to verify your plan before booking.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License No. 1143 and adheres strictly to: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical testing, patient consent, and safety protocols comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic data is encrypted, stored securely, and never shared without your explicit consent.
Clinical & Logistical Metadata
| Test Name | OPTN Gene Glaucoma (Open-Angle Type 1E) – Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks |
| Sample Type / Matrix | 3-5 mL Whole Blood (EDTA tube) or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) – Full OPTN gene coverage |
| ICD-10-CM Code | H40.11 |
| LOINC Code | 93823-1 |
| DHA Facility License & Laboratory Address | License No: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians