Test Price
2,500 AED✅ Home Collection Available
Bacterial Whole Genome Sequencing (WGS) – Illumina Platform in UAE | 2500 AED
Executive Summary & Core Metrics
Executive Summary
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next-Generation Sequencing (NGS) processing, utilizing Illumina's gold-standard reference-based assembly pipeline for definitive bacterial identification and antimicrobial resistance (AMR) profiling.
Premium Logistics: Hospital-Grade Home Collection available 8 AM – 11 PM daily via ISO-Certified Cold-Chain transport. VIP Mobile Phlebotomy ensures sample integrity from collection to laboratory, with real-time temperature monitoring throughout the 4-week analytical turnaround.
Clinical Guidance: Complimentary Telephonic Post-Test Clinical Consultation with a qualified clinical geneticist to interpret genomic findings and guide actionable clinical decisions.
Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731. We coordinate with all major UAE insurers for seamless reimbursement.
Test Overview & Methodology
Bacterial Whole Genome Sequencing (WGS) via the Illumina platform is the most comprehensive molecular diagnostic tool available for characterizing bacterial isolates at single-nucleotide resolution. This test decodes the entire bacterial genome — approximately 2–6 million base pairs — enabling precise species identification, virulence factor detection, antimicrobial resistance gene profiling, and epidemiological outbreak tracing in a single workflow.
| Feature | Our: Illumina WGS | Closest Alternative: Targeted PCR / Culture |
|---|---|---|
| Diagnostic Resolution | Single-nucleotide variant (SNV) level; full-genome coverage | Limited to pre-selected gene targets; ~0.01% of genome |
| Methodology | Illumina NGS with reference-based assembly & de novo analysis | PCR amplification or phenotypic culture with biochemical ID |
| AMR Gene Detection | Comprehensive — detects all known resistance determinants simultaneously | Limited — only tests for 3–10 pre-specified resistance genes |
| Turnaround Time | 4 weeks (including bioinformatic analysis & clinical annotation) | 3–7 days (culture-dependent; slow-growing organisms extend timeline) |
| Epidemiological Typing | MLST, cgMLST, and SNP-based phylogeny in a single assay | Requires separate PFGE or serotyping — additional cost and time |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (Consultant Medical Genetics | DHA License: 9294403) notes:
"Bacterial whole genome sequencing reveals the complete genetic blueprint of the infecting organism — including every resistance gene and virulence factor. While the four-week turnaround demands patience, this depth of information enables your physician to move beyond empiric therapy and select a targeted antibiotic strategy. In the fight against antimicrobial resistance, complete genomic insight is our most powerful tool."
Medication Safety Advisory
Do not discontinue, modify, or self-adjust any prescribed antibiotic, antimicrobial, or immunosuppressive therapy without consulting your treating physician. Interrupting antibiotics based on preliminary symptoms or unverified information may lead to treatment failure, disease relapse, or emergence of multi-drug resistant organisms. Only your doctor can correlate genomic results with your full clinical picture.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria (Do Not Proceed with Home Collection):
- Active, uncontrolled bleeding disorder or INR > 3.0 (verify with treating physician)
- Inability to provide adequate venous access for whole blood collection
- Known allergy to antiseptic agents used in phlebotomy (chlorhexidine, iodine)
- Patient is a minor under 18 years without guardian consent – per UAE regulatory provisions
🚨 Emergency Red Flags — Seek Immediate Medical Attention:
- Fever exceeding 39°C unresponsive to antipyretics
- Altered mental status, confusion, or loss of consciousness
- Signs of sepsis: rapid heart rate, hypotension, mottled skin, or oliguria
- Severe localized pain with spreading erythema or crepitus
- Difficulty breathing or oxygen saturation below 92%
Patient FAQ & Clinical Guidance
1. What is bacterial whole genome sequencing, and how does the Illumina platform work?
Bacterial whole genome sequencing (WGS) decodes the complete DNA blueprint of a bacterial isolate by fragmenting its genome into millions of short reads, sequencing them in parallel on the Illumina platform, and computationally reassembling the reads against a curated reference database. This process identifies every gene present — including those conferring antibiotic resistance, virulence factors, and metabolic pathways — with base-pair-level accuracy. The resulting data enables your physician to select targeted antimicrobial therapy, avoiding broad-spectrum empiric treatments that contribute to resistance. The Illumina platform is globally recognized as the gold standard for clinical bacterial genomics due to its unmatched read accuracy (>99.9%) and high throughput capacity.
2. Why is Illumina-based WGS superior to traditional culture-based identification methods?
Illumina-based WGS surpasses traditional culture methods by providing culture-independent, comprehensive genomic data within a single assay, detecting slow-growing, fastidious, and non-culturable organisms that conventional microbiology would completely miss. Traditional culture relies on viable organisms growing on selective media — a process that can fail for up to 60% of clinically relevant bacteria. WGS bypasses this limitation entirely, working directly from extracted DNA. Furthermore, phenotypic susceptibility testing provides only qualitative sensitivity results, whereas WGS identifies the precise genetic mechanism of resistance (e.g., specific beta-lactamase variants, efflux pump mutations), enabling more nuanced therapeutic decisions and supporting antimicrobial stewardship programs across UAE healthcare facilities.
3. What are the clinical applications of bacterial genome analysis, and how will my results be reported?
Bacterial genome analysis serves multiple critical clinical functions including definitive pathogen identification, comprehensive antimicrobial resistance profiling, virulence factor characterization, and molecular epidemiological typing for infection control and outbreak investigation. Your results will be delivered as a structured clinical report containing: (1) species-level taxonomic identification with confidence scoring, (2) a curated list of detected antimicrobial resistance genes correlated with expected phenotypic resistance patterns, (3) virulence gene inventory with clinical significance annotations, (4) multi-locus sequence typing (MLST) for epidemiological tracking, and (5) a plain-language clinical interpretation summary suitable for sharing with your treating physician. The raw sequencing data (FASTQ files) and assembled genome are also available upon request for academic or research purposes, in compliance with UAE PDPL data privacy regulations.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Privacy
- Licensed by Dubai Health Authority (DHA) — Facility License No. 1143
- Operated by DNA Labs UAE — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
- Accredited ISO 9001:2015 Quality Management System — Certificate No. INT/EGQ/2509DA/3139
- Strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) — all genomic data encrypted and stored within UAE sovereign data centers
- Compliant with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields
- Sample collection and handling adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability for clinical safety and patient consent
Clinical & Logistical Metadata
| Test Name | Bacterial Whole Genome Sequencing (WGS) – Illumina Platform |
| Price (AED) | 2,500 AED |
| Turnaround Time | 4 weeks |
| Sample Type / Matrix | Whole Blood (for metagenomic analysis) or Bacterial Isolate |
| Methodology Used | Illumina Next-Generation Sequencing (NGS) with reference-based assembly and de novo analysis |
| ICD-10-CM Code | B96.89 (Other specified bacterial agents as the cause of diseases classified elsewhere) |
| LOINC Code | 81267-0 (Bacterial genome sequencing by NGS) |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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