Test Price
2,800 AED✅ Home Collection Available
ANLN Gene Focal Segmental Glomerulosclerosis Type 8 (FSGS8) Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
This comprehensive genetic test delivers accurate diagnosis of ANLN gene variants associated with focal segmental glomerulosclerosis type 8, fully compliant with DHA licensing and UAE data protection frameworks.
Test Overview & Methodology
This next-generation sequencing (NGS) test examines the entire coding region of the ANLN gene to identify pathogenic variants responsible for autosomal dominant focal segmental glomerulosclerosis type 8 (FSGS8), guiding precise diagnosis and familial risk assessment. The assay employs the Illumina® platform with confirmatory Sanger sequencing for all clinically significant variants, achieving 99.9% analytic sensitivity and specificity.
| Feature | Our Test (ANLN NGS) | Closest Alternative |
|---|---|---|
| Precision | 99.9% analytic sensitivity with Sanger confirmation | Single‑gene Sanger only; may miss deep intronic variants |
| Methodology | Next‑Generation Sequencing (Illumina® platform) + Sanger verification | PCR‑based Sanger sequencing of selected exons |
| Turnaround | 3–4 Weeks (expedited reporting available) | 6–8 Weeks |
Physician Insight & Safety Protocols
"A positive ANLN result must be interpreted within the full clinical context including renal biopsy histology, proteinuria quantification, and detailed family pedigree. This test enables early surveillance and personalised management pathways, but all therapeutic decisions require multidisciplinary collaboration between nephrology and genetics specialists." — Ms. Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Clinical Safety Advisory
Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Genetic test results do not replace ongoing nephrology care.
Emergency Red Flags – Seek Immediate Care If:
- Sudden anuria or oliguria (urine output <100 mL/24 h)
- Uncontrolled hypertension (≥180/120 mmHg) with neurological symptoms
- Severe hyperkalemia (K⁺ >6.5 mmol/L) or pulmonary oedema
Exclusion Criteria – Do Not Proceed Without Medical Clearance
- Untreated severe anaemia (Hb <7 g/dL) or bleeding diathesis
- Acute nephritic syndrome with rapidly deteriorating kidney function
- Minors without legal guardian consent per UAE Federal Decree-Law No. 4 of 2016 on Medical Liability
- Patients who have undergone allogeneic bone marrow transplant (donor DNA may interfere)
Patient FAQ & Clinical Guidance
1. What does the ANLN gene test detect?
This NGS test detects pathogenic variants in the ANLN gene causing type 8 focal segmental glomerulosclerosis. It analyses the entire ANLN coding sequence to identify mutations linked to proteinuria and progressive kidney damage, supporting accurate diagnosis and family screening.
2. How do I prepare for the ANLN genetic blood draw?
No fasting is required. A certified phlebotomist collects 3–5 mL of venous blood in an EDTA tube. Prior to collection, you will have a mandatory genetic counselling session to document family history and obtain informed consent, in compliance with UAE PDPL and Federal Law No. 2 of 2019.
3. Is the test covered by UAE health insurance?
Many UAE insurers cover genetic FSGS testing when medically indicated. Our insurance team confirms coverage under your policy in real time using your Emirates ID via WhatsApp +971 54 548 8731. For self‑pay patients, the cost is 2,800 AED, inclusive of home collection and post‑test tele‑guidance. The service complies with UAE PDPL and ISO 9001:2015 standards.
UAE Regulatory & Data Privacy Adherence
This test is performed under the strict data protection framework of Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic information is encrypted, access‑controlled, and processed exclusively within UAE‑based secure servers. Clinical safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE holds DHA Facility License No. 1143 and operates under ISO 9001:2015 quality management (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | ANLN Gene Focal Segmental Glomerulosclerosis Type 8 (FSGS8) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next-Generation Sequencing (Illumina®) + Sanger Confirmation |
| ICD-10-CM Code | N04.1 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians