Test Price
2,800 AED✅ Home Collection Available
ZNF711 Gene Genetic Test (X-Linked Intellectual Disability Type 97) in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 certified NGS sequencing and bioinformatics pipeline. Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM. Clinical Guidance: Post-test telephonic guidance with a licensed genetic counselor. Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This genetic test uses Next Generation Sequencing (NGS) to analyze the entire coding region of the ZNF711 gene, diagnosing X-linked intellectual disability type 97 (XLID97). It delivers a definitive molecular diagnosis for affected males and carrier status for females.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision / Sensitivity | 99.9% diagnostic sensitivity with deep coverage ≥100x | ~98% sensitivity; limited to known variants only |
| Method | Full gene NGS + deletion/duplication analysis | Single-gene PCR & amplicon Sanger |
| Turnaround Time | 3–4 weeks | 6–8 weeks |
| Coverage | All exons, splice sites, and known intronic variants | Only targeted amplicons; may miss large rearrangements |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics licensed by the DHA, I want to reassure families that a positive diagnosis from this test provides clarity—not a limitation—opening doors to targeted interventions and accurate genetic counseling. Always correlate NGS findings with the full clinical picture, including developmental milestones and family history. I strongly recommend that all results be reviewed with a clinical geneticist to understand recurrence risks and management plans.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA License: 9294403
Medication & Safety Advisory
Medication & Safety Notice
Do not discontinue prescribed medication without consulting your doctor.
This genetic test is for diagnostic purposes only and does not replace clinical evaluation. Continue all therapies unless instructed otherwise by your physician.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide informed consent (minors require legal guardian signature). Active uncontrolled bleeding disorder or severe anemia precluding safe blood draw.
- Exclusion: Unstable medical condition where home phlebotomy may be contraindicated (e.g., severe hypotension, acute infection).
- Emergency Red Flag: If you experience chest pain, difficulty breathing, fainting, or severe swelling at the blood draw site shortly after sample collection, seek immediate emergency medical attention or call 998.
- Post-procedure: Watch for signs of infection (redness, warmth, pus) at the puncture site within 48 hours.
Patient FAQ & Clinical Guidance
1. What is ZNF711 X-linked intellectual disability and how is it tested?
The ZNF711 gene test analyzes DNA through Next Generation Sequencing to identify pathogenic variants causing X-linked intellectual disability type 97, an inherited condition primarily affecting males.
This condition is characterized by developmental delay, speech impairment, and mild to moderate intellectual disability. Testing requires a blood sample, extracted DNA, or a dried blood spot on an FTA card. Our NGS pipeline covers all coding exons and splice junctions, with a 99.9% sensitivity rate. A pre-test genetic counseling session is mandatory to ensure proper family pedigree documentation and informed consent.
2. What does the test result mean for my child and family planning?
A pathogenic ZNF711 variant confirms the molecular diagnosis, enabling accurate prognosis, tailored educational support, and informed reproductive decisions for the entire family.
A positive result in a male child establishes X-linked inheritance, meaning the mother is usually a carrier and has a 50% risk of passing the variant to each son. Carrier testing for at-risk female relatives becomes available. A variant of uncertain significance (VUS) is not diagnostic and requires periodic reanalysis. Results must be interpreted by a clinical geneticist in the context of the child’s full clinical picture.
3. How accurate is NGS for detecting ZNF711 mutations compared to older methods?
Our NGS achieves 99.9% analytical sensitivity and specificity for single nucleotide variants and small insertions/deletions within the ZNF711 gene, surpassing traditional Sanger sequencing’s limitations.
NGS provides deep, uniform coverage across the entire gene, enabling detection of mosaic variants (as low as 10% allele fraction) and copy number changes that single-gene Sanger may miss. All pathogenic and likely pathogenic variants are confirmed by orthogonal methods when required. Our laboratory participates in external quality assurance (EMQN) and adheres to ISO 9001:2015, ensuring world-class accuracy.
UAE Regulatory & Data Privacy Adherence
Compliance Framework
This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted and stored within UAE borders. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
ISO 9001:2015 Certified: INT/EGQ/2509DA/3139.
Clinical & Logistical Metadata
| Test Name | ZNF711 Gene Genetic Test (X-Linked Intellectual Disability Type 97) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood, extracted DNA, or dried blood spot on FTA card |
| Methodology Used | Next Generation Sequencing (NGS) with deletion/duplication analysis |
| ICD-10-CM Code | Q87.8 |
| LOINC Code | 81247-9 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians