Test Price
2,800 AED✅ Home Collection Available
XRCC4 Gene Genetic Test for Short Stature, Microcephaly, and Endocrine Dysfunction in Dubai, UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM – 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Consultation with Board-Certified Genetic Counselor.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Regulatory Compliance: DHA Facility License 1143, Premises 105, Building 33, Dubai Healthcare City.
Test Overview & Methodology
The XRCC4 gene test employs whole-gene sequencing via Next-Generation Sequencing (NGS) to identify pathogenic mutations associated with short stature, microcephaly, and endocrine dysfunction. This non-invasive analysis requires a standard peripheral whole blood sample or extracted DNA and delivers results with 99.9% sensitivity under ISO 9001:2015 protocols. Results are typically available within 3–4 weeks, enabling timely genetic counseling and management planning.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | Full gene NGS coverage with variant confirmation | Limited targeted mutation panel |
| Methodology | Next-Generation Sequencing (NGS) | Sanger sequencing (single gene) |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA License 9294403), states: "While a pathogenic variant in XRCC4 strongly correlates with growth failure, microcephaly, and endocrine disturbances, interpretation must always integrate the full clinical picture. This test provides essential prognostic insight, guiding early endocrine interventions and cancer surveillance. I encourage families to discuss all findings with their genetic counselor and pediatric endocrinologist for a comprehensive management plan."
Safety Advisory
ER Red Flags: If the patient experiences severe growth arrest, unexplained recurrent infections, or neurological deterioration, seek immediate medical evaluation regardless of pending test results.
Exclusion Criteria
Inability to provide informed consent (legal guardian required, per Federal Decree-Law No. 4 of 2016 on Medical Liability). Active severe illness precluding safe blood draw. Known alternative diagnosis that does not warrant genetic testing.
Patient FAQ & Clinical Guidance
1. What is the XRCC4 gene test and who should consider it?
This test sequences the entire XRCC4 gene to detect mutations causing short stature, microcephaly, and endocrine dysfunction. It is recommended for children with unexplained growth failure, microcephaly, and hormonal abnormalities, and for families seeking a definitive genetic diagnosis.
2. How is the sample collected and what is the turnaround time?
A peripheral whole blood sample is collected via VIP mobile phlebotomy at your home (daily 8 AM – 11 PM) with temperature-controlled cold-chain transport. Alternatively, extracted DNA can be submitted. Results are delivered within 3–4 weeks.
3. How accurate is the test and what preparation is needed?
The test offers 99.9% diagnostic sensitivity under ISO 9001:2015 protocols. Preparation includes a mandatory pre-test genetic counseling session to document family history (pedigree) and obtain informed consent in accordance with DHA guidelines and Federal Decree-Law No. 4 of 2016.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance: This service strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted and securely handled. Accredited by ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). DHA Facility License: 1143.
Clinical & Logistical Metadata
| Test Name | XRCC4 Gene Genetic Test (Short Stature, Microcephaly, Endocrine Dysfunction) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood or extracted DNA (VIP Mobile Phlebotomy & Cold-Chain Home Collection) |
| Methodology Used | Next-Generation Sequencing (NGS) – Whole Gene Analysis |
| ICD-10-CM Code | Q02 (Microcephaly), R62.52 (Short stature) |
| LOINC Code | 81321-7 (XRCC4 gene mutation analysis) |
| DHA Facility License & Address | License 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians