Test Price
2,800 AED✅ Home Collection Available
Von Willebrand Factor (VWF) Gene Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
The Von Willebrand Factor (VWF) Gene Genetic Test uses Next‑Generation Sequencing (NGS) to identify pathogenic variants in the VWF gene with 99.9% diagnostic sensitivity. This definitive molecular diagnosis supports hematologists and clinical geneticists in managing von Willebrand disease, the most common inherited bleeding disorder. The test is performed at DNA Labs UAE under DHA license 1143 and ISO 9001:2015 certified processes.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily 8 AM – 11 PM.
- Clinical Guidance: Post‑test telephonic counseling with a Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The VWF Gene Genetic Test employs full gene sequencing by NGS to detect small nucleotide variants, insertions, and deletions across all coding exons and flanking intronic regions. Variants are classified according to ACMG/AMP guidelines and correlated with clinical phenotype. This provides a precise molecular diagnosis that cannot be achieved with traditional VWF activity or antigen assays alone.
| Feature | Our VWF NGS Test | Closest Alternative (VWF Activity/Ag Assays) |
|---|---|---|
| Precision | 99.9% Diagnostic Sensitivity | Variable; lower sensitivity for type 2 VWD |
| Methodology | Next‑Generation Sequencing (NGS) | Immunological/functional assays only |
| Turnaround Time | 3 – 4 Weeks | 2 – 5 Days |
| Clinical Depth | Full gene sequencing + variant interpretation | No genetic variant data |
Physician Insight & Safety Protocols
"As a Consultant Medical Geneticist, I consider the VWF Gene Genetic Test a cornerstone for diagnosing von Willebrand disease when clinical suspicion is high. The NGS approach captures the full mutational spectrum, including rare variants missed by biochemical assays. However, the results must always be interpreted alongside bleeding history and laboratory phenotype. My team provides dedicated post‑test counseling to help you understand the implications for treatment and family screening."
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Medication Advisory
Do not discontinue any prescribed anticoagulant or antiplatelet medication without consulting your doctor. Abrupt changes may increase the risk of thrombosis or bleeding. Inform your genetic counselor about all current medications before sample collection.
Safety Exclusion Criteria & Red Flags
- Recent blood transfusion (< 4 weeks) may interfere with DNA interpretation.
- Active severe bleeding or hemodynamic instability requires immediate emergency care.
- History of bone marrow transplant within the past 6 months.
- Immediate medical attention (ER) if: sudden severe mucosal bleeding, hematemesis, melena, or signs of intracranial hemorrhage (severe headache, focal neurology).
Patient FAQ & Clinical Guidance
1. What is the purpose of this test and who should consider it?
This test detects mutations in the VWF gene that cause von Willebrand disease. It is recommended for individuals with unexplained bleeding, heavy menstrual bleeding, family history of VWD, or pre‑surgical evaluation when standard coagulation tests are inconclusive.
2. How is the sample collected and what preparation is needed?
Sample collection is via a simple venipuncture (whole blood) or a finger‑prick on an FTA card. No fasting is required, but please inform us of any recent transfusions or clotting factor therapy. A pre‑test genetic counseling session is included to document family history and obtain informed consent.
3. When will I receive my results and how are they interpreted?
Turnaround time is 3 to 4 weeks. Your report includes a detailed variant classification (pathogenic, likely pathogenic, benign, etc.) and is reviewed by our Consultant Medical Geneticist, who provides telephonic clinical correlation and guidance for family cascade testing.
UAE Regulatory & Data Privacy Adherence
This service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access‑controlled, and processed solely for diagnostic purposes with your explicit consent. The laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and follows CLIA-equivalent quality standards.
Clinical & Logistical Metadata
| Test Name | Von Willebrand Factor (VWF) Gene Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or FTA card |
| Methodology Used | Next‑Generation Sequencing (NGS) – Illumina platform |
| ICD-10-CM Code | D68.0 (Von Willebrand's disease) |
| LOINC Code | 82652-2 (VWF gene mutation analysis in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians