Test Price
2,800 AED✅ Home Collection Available
VIPAS39 Gene NGS Test – Arthrogryposis, Renal Dysfunction & Cholestasis Type 2 | 2800 AED | 2026 DHA Guidelines
تحليل جين VIPAS39 لمتلازمة التقفع المفصلي والفشل الكلوي والركود الصفراوي من النوع الثاني في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – ملخص تنفيذي
- ✓ Diagnostic Accuracy: 99.9% analytical sensitivity via ISO 9001:2015‑certified Next‑Generation Sequencing at our DHA‑licensed genetic facility.
- ✓ Premium Logistics: Hospital‑grade home collection (8 AM – 11 PM) with ISO‑certified cold‑chain transport and VIP mobile phlebotomy.
- ✓ Clinical Guidance: Complimentary telephonic post‑test session with a genetic counsellor to interpret results and plan next steps.
- ✓ Insurance & Billing: Direct insurance verification via WhatsApp at +971 54 548 8731. Facility license No. 9834453.
يضمن التحليل الجيني لجين VIPAS39 تشخيصًا دقيقًا لمتلازمة التقفع المفصلي والفشل الكلوي والركود الصفراوي من النوع الثاني (متلازمة ARC) وفق أحدث إرشادات هيئة الصحة بدبي لعام 2026، مع استشارة وراثية شاملة وسحب منزلي معتمد.
Clinical Overview of the VIPAS39 NGS Test
The VIPAS39 gene next‑generation sequencing (NGS) test interrogates the entire coding region to detect pathogenic variants responsible for Arthrogryposis, Renal dysfunction, and Cholestasis (ARC) syndrome type 2 – a rare autosomal recessive disorder with multi‑system involvement. يكشف تحليل تسلسل الجيل التالي لجين VIPAS39 عن الطفرات المسببة للمتلازمة النادرة التي تجمع بين تقفع المفاصل والقصور الكلوي والركود الصفراوي.
| Feature | Our VIPAS39 NGS Test | Whole Exome Sequencing (Alternative) |
|---|---|---|
| Precision | Targeted deep sequencing of VIPAS39 – 99.9% sensitivity for coding variants | Broader coverage but may miss deep intronic or low‑coverage regions in VIPAS39 |
| Methodology | NGS with copy‑number variant analysis (LC‑MS/MS compatible validation) | Standard exome capture; often requires reflex targeted confirmation |
| Turnaround | 3–4 weeks with expedited genetic counselling report | 4–8 weeks; interpretation may be less disease‑focused |
Physician Insight & Safety Protocol
“As a clinician, I see the VIPAS39 test as a window of opportunity – a precise genetic answer that can finally direct a family toward the right multidisciplinary care. However, every result must be interpreted alongside renal ultrasound, liver function, and joint examinations; a mutation does not always predict severity. I strongly encourage all patients to undergo formal genetic counselling before and after testing.”
– Dr. Prabhaka Reddy, DHA License 61713011
Medication Warning
Do not discontinue any prescribed medication (ursodeoxycholic acid, antihistamines, renal support) without consulting your physician. This test is for diagnostic clarification, not therapeutic replacement.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals unable to provide a 3‑generation pedigree during genetic counselling, or those unwilling to sign informed consent as per UAE Federal Decree‑Law No. 41 of 2024 (Art. 87) and CDS Law 2026.
- Seek emergency care immediately if: Acute jaundice with severe pruritus, oliguria/anuria (≤0.5 mL/kg/h in children), or sudden worsening of joint contractures with dehydration.
Frequently Asked Questions – Patient Guidance
What is the VIPAS39 gene test and why is it ordered for an infant with contractures and jaundice?
The VIPAS39 NGS test identifies disease‑causing mutations in the VIPAS39 gene, confirming a diagnosis of ARC syndrome type 2 when a child presents with arthrogryposis, renal dysfunction, and cholestasis. يحدد الاختبار الطفرات الممرضة في جين VIPAS39 لتأكيد تشخيص متلازمة ARC من النوع الثاني عند الرضع الذين يعانون من تقفع المفاصل واليرقان.
How should I prepare my child for the blood draw or buccal swab at home?
No fasting or medication changes are required; simply ensure the child is well‑hydrated and the home collection environment is calm to minimise distress during the procedure. لا يلزم الصيام أو تغيير الأدوية، ويُفضَّل أن يكون الطفل رطبًا وفي بيئة هادئة أثناء السحب المنزلي.
Will my insurance cover the 2800 AED cost and does the report comply with UAE privacy laws?
Our team verifies coverage directly through WhatsApp; the and genetic report are fully compliant with UAE Personal Data Protection Law (PDPL) and Federal Decree‑Law No. 41 of 2024, ensuring your data never leaves secure DHA‑licensed servers. يتحقق فريقنا من التغطية التأمينية عبر الواتساب، وجميع التقارير متوافقة مع قانون حماية البيانات الشخصية الإماراتي والمرسوم بقانون اتحادي رقم 41 لسنة 2024.
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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