Test Price
2,800 AED✅ Home Collection Available
USF1 Gene Hyperlipidemia, Familial Combined Susceptibility – Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Diagnostic Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited next-generation sequencing (NGS) processing.
- Premium Logistics: VIP mobile phlebotomy with temperature-controlled cold-chain home collection, available daily from 8 AM to 11 PM.
- Clinical Guidance: Complimentary telephonic post-test genetic counselling session with a senior clinical geneticist to contextualise results.
- Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731 – most UAE payers accepted.
Test Overview & Methodology
This advanced NGS-based genetic test screens the entire coding region of the USF1 gene for inherited pathogenic variants that predispose to familial combined hyperlipidemia. The condition elevates both cholesterol and triglycerides and accelerates atherosclerotic cardiovascular disease. Early identification of susceptibility variants enables proactive lipid management and lifestyle intervention before irreversible vascular damage occurs.
| Feature | Our USF1 NGS Test | Standard Lipid Panel |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) of entire USF1 gene | Enzymatic colorimetric blood lipid measurement |
| Clinical Insight | Direct genetic susceptibility – identifies risk before lipid levels rise | Reflects current lipid status only; cannot predict inherited risk |
| Turnaround Time | 3–4 weeks | Same day |
| Diagnostic Sensitivity | 99.9% for known pathogenic USF1 variants | Not applicable to genetic risk |
| Guideline Alignment | DHA/MOHAP precision medicine pathways for familial dyslipidaemia | General screening only |
Physician Insight & Safety Protocols
“Identifying a pathogenic USF1 variant provides a window of opportunity to intervene years before clinical hyperlipidaemia manifests. In my practice, I integrate these results with the patient’s family pedigree, lipid trajectory, and metabolic profile to design a highly personalised cardioprotective strategy. Genetic risk is never a verdict—it is a roadmap for prevention.”
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Medication Safety Advisory
Do not discontinue any prescribed lipid-lowering medication, statins, or other cardiovascular drugs without consulting your treating physician. This genetic test supplements, but never replaces, ongoing clinical management. Always share your genetic report with your prescribing doctor before making any treatment changes.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Pregnant individuals or those planning pregnancy without prior genetic counselling; minors (under 18) without documented legal guardian consent as per Federal Decree-Law No. 4 of 2016 on Medical Liability; patients with acute febrile illness or recent blood transfusion (wait 4 weeks before sampling).
- Emergency Red Flags: If you experience sudden chest pain, shortness of breath, severe headache, or neurological symptoms, seek emergency medical care immediately – do not wait for test results.
Patient FAQ & Clinical Guidance
1. What exactly does the USF1 genetic test detect, and how accurate is it?
This NGS‑based test identifies inherited pathogenic variants in the USF1 gene that cause familial combined hyperlipidemia with 99.9% diagnostic sensitivity. It sequences the entire coding region to pinpoint even rare mutations, allowing your doctor to stratify cardiovascular risk long before traditional lipid tests show abnormalities. The result is reported with clear American College of Medical Genetics and Genomics (ACMG) variant classification.
2. How is the sample collected, and what is the turnaround time?
A certified phlebotomist collects a simple peripheral blood sample during a convenient home visit, transported under ISO‑certified temperature-controlled cold chain. Alternatively, you may visit our Dubai Healthcare City laboratory for walk-in collection. Your detailed clinical report is ready in 3 to 4 weeks, and a complimentary post-test tele-consultation with a genetic counsellor is included in the service.
3. Will my insurance cover this test, and how is my genetic data protected?
Most UAE insurers reimburse this test under cardiovascular risk screening; we verify coverage before collection via WhatsApp at +971 54 548 8731. Your genetic data is handled in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All results are encrypted, access-controlled, and released only with your signed informed consent.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and adheres to the highest standards of genetic data governance. All patient information is processed in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic privacy is protected by design—encrypted storage, role-based access, and explicit consent workflows ensure full regulatory compliance.
Clinical & Logistical Metadata
| Test Name | USF1 Gene Hyperlipidemia, Familial Combined Susceptibility – Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) |
| Methodology Used | Next‑Generation Sequencing (NGS) |
| ICD-10-CM Code | E78.49 |
| LOINC Code | 92606-2 |
| DHA Facility License & Laboratory Address | License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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