Test Price
2,800 AED✅ Home Collection Available
UNG Gene Immunodeficiency Type 5 with Hyper-IgM (Genetic Test) in UAE | 2800 AED | DHA Licensed Lab
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy via Temperature-Controlled Cold-Chain Home Collection – Available daily 8 AM to 11 PM.
Clinical Guidance: Dedicated telephonic post-test result interpretation by qualified genetics professionals.
Insurance: Direct Billing Verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
This next‑generation sequencing (NGS) test fully analyzes the UNG gene to detect pathogenic variants causing Immunodeficiency Type 5 with Hyper‑IgM syndrome. It provides definitive molecular diagnosis, carrier screening, and guides personalized clinical management. The test employs targeted gene capture and high‑throughput sequencing to achieve 99.9% analytical sensitivity with comprehensive coverage of exonic and intronic regions.
| Parameter | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | 99.9% analytical sensitivity, full gene coverage including deep intronic regions | Limited coverage, no detection of deep intronic or copy number variants |
| Methodology | NGS with copy‑number variant (CNV) detection and bioinformatics pipeline | Sanger sequencing – low throughput, no CNV analysis |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I emphasize that a UNG gene result must always be interpreted in conjunction with complete immunological work‑up, family history, and clinical presentation. This test alone does not establish a diagnosis; it is one piece of a comprehensive evaluation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety Advisory – Medication & Immunoglobulin Therapy
Do not discontinue or alter prescribed medication, immunoglobulin replacement, or any immunosuppressive therapy without prior consultation with your treating physician. This genetic test is for diagnostic confirmation only and does not replace ongoing clinical management.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Active severe infection requiring urgent medical intervention, recent blood transfusion (within 72 hours) which may interfere with DNA analysis, inability to provide informed consent, or pregnancy where results may prematurely influence decisions without genetic counseling.
- Emergency Indicators: Sudden onset of severe infection, respiratory distress, or signs of sepsis in a patient with known immunodeficiency require immediate hospital evaluation. This diagnostic test is not a substitute for acute clinical care.
Patient FAQ & Clinical Guidance
1. What is the UNG gene test and why is it needed?
This NGS test identifies disease‑causing variants in the UNG gene, which are responsible for Immunodeficiency Type 5 with Hyper‑IgM syndrome. The test is recommended for individuals with recurrent infections, low immunoglobulin levels, or a family history of primary immunodeficiency. It differentiates this condition from other hyper‑IgM syndromes and guides treatment decisions.
2. How is the test performed and what sample is required?
A blood sample (or extracted DNA / dried blood spot on FTA card) is collected by our licensed phlebotomist. For your convenience, we offer VIP Mobile Phlebotomy between 8 AM and 11 PM, using a temperature‑controlled cold‑chain transport kit to preserve DNA integrity until the laboratory receives the specimen. Alternatively, you may visit our Dubai Healthcare City facility for sample collection.
3. How long do results take and what is the cost?
Results are typically available within 3–4 weeks. The total cost is 2,800 AED. We offer direct insurance billing – send a WhatsApp message to +971 54 548 8731 for pre‑authorization verification. Post‑result telephonic guidance from a qualified medical geneticist is included in the service.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Compliance
This diagnostic service is fully compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is processed with strict confidentiality, stored in encrypted systems, and accessed only by authorized clinical staff. Clinical safety and patient consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | UNG Gene Immunodeficiency Type 5 with Hyper‑IgM (Genetic Test) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood, extracted DNA, or dried blood spot (FTA card) – VIP Mobile Phlebotomy & Cold‑Chain Home Collection available |
| Methodology Used | Next‑Generation Sequencing (NGS) with targeted gene capture, including CNV analysis |
| ICD‑10‑CM Code | D82.4 (Hyper‑IgM immunodeficiency) accompanied by Z15.89 if genetic carrier |
| LOINC Code | 32387‑5 (DNA sequencing, targeted gene) |
| DHA Facility License & Laboratory Address | License: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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