Test Price
2,800 AED✅ Home Collection Available
UNC13B Genetic Test for Autism Spectrum Disorder in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189:2022 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This next-generation sequencing (NGS) test analyses the entire coding region of the UNC13B gene to identify pathogenic variants linked to autism spectrum disorder (ASD) susceptibility. Results are interpreted according to ACMG standards, integrating DHA genomic reporting guidelines.
| Feature | Our Test (UNC13B NGS) | Closest Alternative (Microarray / Panel) |
|---|---|---|
| Precision | Single‑nucleotide & indel resolution; detects deep intronic variants | CNV-focused; misses most sequence‑level mutations |
| Methodology | NGS (Illumina® NovaSeq™, 300x coverage) + Sanger validation | Chromosomal microarray (CMA) or limited gene panel |
| Turnaround Time | 3–4 Weeks | 4–8 Weeks (often fragmented) |
Physician Insight & Safety Protocols
“A positive UNC13B variant does not diagnose autism on its own. It must be correlated with clinical evaluation, developmental history, and family segregation. This test empowers early intervention pathways, but results require specialised genetic counselling.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration: 9294403)
Safety Advisory: Pre-Test Genetic Counselling Requirement
A formal genetic counselling session is mandatory before sample collection. This session constructs a detailed pedigree chart and reviews the implications of potential results. No fasting is required. The patient must provide previous neurodevelopmental assessments and family history.
Safety Exclusion Criteria & Emergency Red Flags
- Not suitable for patients with acute neurological decompensation or active sepsis.
- Minors require parental consent and a pre‑test genetic counselling session as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Emergency warning: If the individual displays rapid regression, self‑harm, or severe behavioural crisis, seek immediate medical attention at an ER; do not rely on pending genetic results.
Patient FAQ & Clinical Guidance
1. What is the UNC13B test and why is it done?
This targeted NGS test identifies mutations in the UNC13B gene that are strongly associated with non‑syndromic autism spectrum disorder, enabling precise genetic diagnosis and risk assessment for family members.
2. How accurate is this compared to other autism genetic tests?
Our NGS assay with 300x mean coverage and Sanger validation achieves 99.9% analytical sensitivity and specificity for UNC13B variants, far exceeding microarray‑based screens that miss the majority of causative point mutations.
3. Will my insurance cover the 2800 AED cost?
Coverage depends on your policy’s genetic testing benefits; we provide direct billing verification via WhatsApp (+971 54 548 8731) before sample collection, and many UAE insurers now reimburse diagnostic NGS tests for neurodevelopmental disorders when medically indicated.
UAE Regulatory & Data Privacy Adherence
- Data Privacy: All genomic data processed and stored in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Data Security: Adherence to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability & Consent: Patient safety and informed consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Laboratory Accreditation: ISO 15189:2022 and ISO 9001:2015 certified.
- Licensed Facility: DHA Facility License No. 1143, Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | UNC13B Gene Genetic Test for Autism Spectrum Disorder |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | EDTA Whole Blood, Dried Blood Spot, or Extracted DNA |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger Validation, 300x coverage |
| ICD-10-CM Code | F84.0 (Autism Spectrum Disorder) |
| LOINC Code | 21770-0 (UNC13B gene mutation analysis) |
| DHA Facility License & Laboratory Address | DNA Labs UAE – License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians