Also known as: Familial Transient Neonatal Hyperbilirubinemia Genetic Test, UGT1A1 Gene Sequencing for Neonatal Jaundice
Test Price
2,800 AEDโ Home Collection Available
๐ Results in 10-14 Business Days (ISO Fast Track)
UGT1A1 Gene Hyperbilirubinemia (Familial Transient Neonatal) Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
DHA-Aligned Precision Diagnostics
99.9% Diagnostic Sensitivity via ISO 15189:2022 Accredited Next-Generation Sequencing (NGS) processing. Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM. Clinical Guidance: Post-test genetic counseling session included with report delivery. Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This once-in-a-lifetime NGS test decodes the UGT1A1 gene to identify inherited variants causing severe neonatal jaundice and impaired bilirubin metabolism, enabling life-saving early interventions. The assay covers the full coding region, promoter, and intron-exon boundaries for single nucleotide variants (SNVs), insertions, and deletions.
| Feature | Our Test (DHA-Compliant) | Closest Alternative |
|---|---|---|
| Analytical Method | NGS + CNV Analysis | Sanger Sequencing or targeted panel |
| Turnaround Time | 10-14 Business Days (ISO Fast Track) | 4-6 Weeks |
| Coverage | Full gene, promoter, SNVs, indels | Limited to known hotspots |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics, I guide families that this NGS test precisely maps the molecular root of familial transient hyperbilirubinemia. However, the result must always be weighed against the infant's clinical trajectory and bilirubin dynamics. A negative screen does not exclude all causes of neonatal jaundice, and a positive result directs targeted surveillance but does not replace immediate medical assessment."
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety Advisory & Medication Guidance
Important: This test is diagnostic only. Do not alter or cease prescribed phototherapy, phenobarbital, or any other treatment without consulting your physician. The genetic result informs long-term management, while acute jaundice requires immediate clinical intervention.
Patient Exclusion & Emergency Red Flags
- Emergency Contraindication: Infant showing signs of acute bilirubin encephalopathy (lethargy, poor feeding, high-pitched cry) โ seek emergency care immediately.
- Recent Transfusion: Blood transfusion within the last 2 weeks may compromise DNA analysis accuracy.
- Sample Volume: Inability to provide adequate sample volume (heel-prick card or whole blood) may delay processing.
๐จ Immediate ER Referral Required If:
- Jaundice appears within the first 24 hours of life.
- Total serum bilirubin rises >0.5 mg/dL per hour.
- Signs of kernicterus present: arching of back, seizures, apnea.
Patient FAQ & Clinical Guidance
1. What does the UGT1A1 NGS test actually detect?
Answer: This test identifies DNA variants in the entire UGT1A1 gene and its regulatory promoter that cause reduced enzyme activity, leading to severe neonatal jaundice. It provides a definitive molecular diagnosis for familial transient hyperbilirubinemia.
2. How is the sample collected for a newborn?
Answer: A small heel-prick blood drop on an FTA card or a gentle venous draw is sufficient. Our VIP Mobile Phlebotomy service dispatches a trained pediatric specialist to your home for stress-free collection.
3. Will my insurance cover the AED 2,800 cost?
Answer: We verify coverage instantly via WhatsApp; most UAE health plans reimburse this medically necessary genetic test when accompanied by a physician's request. Direct billing is available for approved insurers.
UAE Regulatory & Data Privacy Adherence
This facility strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical safety protocols and patient consent procedures are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | UGT1A1 Gene Hyperbilirubinemia (Familial Transient Neonatal) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 10-14 Business Days (ISO Fast Track) |
| Sample Type / Matrix | Peripheral Whole Blood, Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) + CNV Analysis |
| ICD-10-CM Code | E80.4 |
| LOINC Code | 21748-8 |
| DHA Facility License & Lab Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Lab: DNA Labs UAE |
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Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
Preparation Required
["No specific fasting required for newborns.", "Inform the lab about any recent blood transfusions."]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians