Test Price
2,800 AED✅ Home Collection Available
UBE2A Gene Nascimento-Type X-Linked Syndromic Mental Retardation Genetic Test in UAE | 2800 AED | DHA Licensed Lab
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM – 11 PM) available UAE-wide.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation with a DHA-licensed genetic counsellor.
- Insurance: Direct Billing Verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
This Genetic Test provides definitive molecular diagnosis, informs genetic counselling for families, and supports carrier detection in females. The test uses Next Generation Sequencing (NGS) with Sanger confirmation for full coverage of the UBE2A gene, including all coding exons and flanking splice sites.
| Feature | Our Test (DNA Labs UAE) | Typical Hospital Lab |
|---|---|---|
| Precision | >99.9% analytical sensitivity; full gene coverage with NGS + Sanger confirmation | Variable; may rely on older sequencing or limited panels |
| Method | NGS (Next Generation Sequencing) with ISO 9001:2015 validated workflow | Often Sanger sequencing or commercial kits without full coverage |
| TAT | 3-4 weeks | 6-8 weeks |
Physician Insight & Safety Protocols
Dr. Lina Osama Zaki Quteineh (DHA License: 9294403) emphasises: “A positive UBE2A result is a life‑changing diagnosis that requires compassionate, multidisciplinary care. This test provides definitive answers for families, enabling precise genetic counselling and carrier detection. Please ensure the test is ordered in conjunction with a comprehensive clinical evaluation and developmental history. Our team is committed to supporting you through the entire diagnostic journey.”
Medication Advisory
Do not discontinue any prescribed medication without consulting your doctor. This genetic test does not replace regular medical care or ongoing medication management.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients unable to provide informed consent; test cannot be performed if the sample is compromised (haemolysed, clotted, insufficient DNA).
- Exclusion: This test is not a standalone prenatal screen; it must be accompanied by certified genetic counselling.
- ER Red Flag: If a pathogenic variant is identified in a child with acute neurological deterioration, arrange emergency paediatric neurology consultation immediately.
- ER Red Flag: Do not interpret results as a prognosis without expert clinical input – urgent misinterpretation can lead to unnecessary distress or missed interventions.
Patient FAQ & Clinical Guidance
1. What does the UBE2A NGS test detect and how reliable is it?
Snippet Answer: This test detects single nucleotide variants, small insertions/deletions, and large copy number changes in the UBE2A gene with 99.9% sensitivity, confirming or ruling out Nascimento-type X-linked mental retardation.
The assay uses next-generation sequencing to cover all coding exons and flanking splice sites, followed by orthogonal Sanger confirmation of any pathogenic or likely pathogenic findings. It is considered the gold standard for molecular diagnosis of this ultra-rare condition.
2. How is home collection performed and who is eligible?
Snippet Answer: A DHA-certified phlebotomist arrives at your doorstep between 8 AM and 11 PM to collect a simple blood sample (or DNA FTA card), ensuring cold-chain integrity and VIP comfort.
Adults, children, and even infants can provide a blood sample; for those unable to travel, a one-drop blood spot on an FTA card is acceptable. The service is available UAE-wide and fully complies with UAE PDPL for sample privacy.
3. What is the clinical impact of a positive result?
Snippet Answer: A positive UBE2A result confirms Nascimento-type X-linked intellectual disability, enabling targeted therapies, accurate recurrence risk estimation, and carrier testing for at-risk female relatives.
Physicians can tailor developmental interventions, surveillance for associated anomalies, and plan future prenatal or preimplantation genetic diagnosis if desired. Our post‑result counselling explains all implications in clear, empathetic language.
UAE Regulatory & Data Privacy Adherence
This genetic test is conducted in full compliance with the legal and regulatory framework of the United Arab Emirates. We adhere to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) ensuring all patient data is processed securely and with explicit consent. Additionally, we comply with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for all digital health records and telemedicine services. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability, guaranteeing that every procedure meets the highest ethical and professional standards.
Clinical & Logistical Metadata
| Test Name | UBE2A Gene Nascimento-Type X-Linked Syndromic Mental Retardation Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral blood (EDTA tube) or FTA card (dried blood spot) |
| Methodology Used | Next Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | Q87.8 (Other specified congenital malformation syndromes) |
| LOINC Code | 81314-0 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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ISMS 27001:2022
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