Test Price
2,800 AED✅ Home Collection Available
TSC1 Gene Tuberous Sclerosis Genetic Test in UAE | 2,800 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The TSC1 Gene Tuberous Sclerosis Genetic Test is a definitive molecular diagnostic that sequences the entire TSC1 gene to identify pathogenic variants causing Tuberous Sclerosis Complex (TSC), a multisystem neurogenetic disorder. This advanced test offers unparalleled clarity for patients with neurological symptoms, skin lesions, or a family history of TSC, empowering precision management across neurology, oncology, and genetic counselling.
A detailed clinical history and a mandatory genetic counselling session to draw a pedigree chart of family members affected with Tuberous Sclerosis must be completed. No fasting is required; however, inform the phlebotomist if you are taking anticoagulants. Sample: Blood (3-5 mL in EDTA), Extracted DNA, or one drop of blood on a DNA FTA Card.
| Feature | Our Test (TSC1 NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | >99.9% Sensitivity & Specificity (full gene coverage) | ~95% Analytic Sensitivity (misses large deletions/exon rearrangements) |
| Methodology | Next‑Generation Sequencing (Illumina NovaSeq) – all exons, splice sites | Sanger Sequencing – limited to known hot‑spots; lower throughput |
| Turnaround Time | 3 to 4 Weeks | 1 to 2 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
“Tuberous sclerosis complex diagnosis is a journey of clinical correlation. A positive TSC1 NGS result confirms the etiology, while a negative result does not rule out the disorder; MRI and dermatological findings remain vital. Always interpret genetic data alongside a neurologist or medical geneticist.”
Medication Advisory
Do not discontinue any prescribed medication, especially antiepileptics, without consulting your treating physician.
Safety & Exclusion Criteria
- Exclusion: Patients with severe coagulation disorders (e.g., hemophilia A, factor <1%) – coordinate with hematologist for adjusted collection. Not suitable for individuals who have undergone allogeneic bone marrow transplantation (donor DNA interference).
- ER Red Flags: A seizure lasting longer than 5 minutes, sudden vision loss, or unremitting severe headache (rare after simple venipuncture) requires emergency evaluation – these are signs of the underlying condition, not the test.
Patient FAQ & Clinical Guidance
1. What is the TSC1 gene test?
The TSC1 Gene Tuberous Sclerosis Genetic Test identifies pathogenic variants in the TSC1 gene that cause Tuberous Sclerosis Complex, a hereditary disorder characterized by benign tumors in the brain, kidneys, skin, and other organs, often presenting with epilepsy or intellectual disability.
2. Who should consider this test?
Individuals with clinical signs such as facial angiofibromas, hypomelanotic macules, infantile spasms, or a family history of tuberous sclerosis should pursue this NGS test to confirm a genetic diagnosis and guide lifelong surveillance.
3. How accurate is this genetic test?
With a diagnostic sensitivity exceeding 99.9% and high‑depth coverage of all coding exons, our ISO‑certified NGS provides the definitive TSC1 mutation status, far surpassing the detection limits of conventional Sanger sequencing.
UAE Regulatory & Data Privacy Adherence
Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent are governed under Federal Decree-Law No. 4 of 2016 on Medical Liability. Accredited to ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). DHA Facility License: 1143.
Clinical & Logistical Metadata
| Test Name | TSC1 Gene Tuberous Sclerosis Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood (3–5 mL in EDTA), Extracted DNA, or Buccal Swab / FTA Card |
| Methodology Used | Next‑Generation Sequencing (NGS) – Illumina NovaSeq, full gene coverage including all exons and splice sites |
| ICD-10-CM Code | Q85.1 (Tuberous sclerosis) |
| LOINC Code | 82991-3 (TSC1 gene mutation analysis) |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
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