Test Price
2,800 AED✅ Home Collection Available
TG Gene Thyroid Dyshormonogenesis Type 3 Genetic Test - 2,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Executive Summary
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing.
- Premium Logistics: VIP mobile phlebotomy with temperature-controlled cold-chain home collection (available daily 8 AM - 11 PM).
- Clinical Guidance: Telephonic post-test clinical guidance in result interpretation by a DHA-licensed Consultant Medical Geneticist.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The TG Gene Thyroid Dyshormonogenesis Type 3 Genetic Test detects pathogenic variants in the thyroglobulin (TG) gene responsible for congenital hypothyroidism with goitre. This analysis provides definitive molecular confirmation for suspected dyshormonogenesis, guiding lifelong hormone replacement therapy and family counselling. The test is performed using targeted Next-Generation Sequencing (NGS) covering the full coding region and splice sites, with confirmatory Sanger sequencing for variant validation.
| Feature | Our Test (TG NGS) | Standard Single-Gene Sanger |
|---|---|---|
| Method | Targeted NGS + Sanger validation | Sanger sequencing |
| Coverage | Full coding region + splice sites | Selected exons only |
| Turnaround | 21 calendar days (DHA expedited) | 4–6 weeks |
| Sensitivity | 99.9% for SNVs/indels | ~95% |
Physician Insight & Safety Protocols
“As a DHA-licensed Consultant Medical Geneticist, I emphasize that this test provides definitive molecular confirmation of TG gene variants, enabling precise treatment and informed family planning. The results must always be integrated with clinical findings, biochemical profiles, and imaging for comprehensive management.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Medication Advisory
Do not discontinue prescribed thyroid medications or any hormone therapy without consulting your physician. Abrupt cessation may lead to severe metabolic decompensation. All treatment adjustments must be supervised by a qualified endocrinologist.
Patient Exclusion Criteria & Red Flags
- Unstable acute illness requiring hospitalization – postpone elective genetic testing.
- Known chromosomal disorder impacting sample quality without prior laboratory clearance.
- Failure to provide informed consent or legal guardian consent (mandatory for minors under UAE regulations).
- Seek emergency care immediately if: severe lethargy, hypothermia, or breathing difficulties occur in an infant with suspected hypothyroidism.
Patient FAQ & Clinical Guidance
1. What does a positive TG gene result mean for my child's health?
A positive result confirms a genetic form of thyroid dyshormonogenesis, enabling precise levothyroxine dosing from birth to prevent intellectual disability and growth failure, as per UAE newborn screening protocols.
2. How is the sample collected and is a hospital visit necessary?
A certified phlebotomist collects a single blood sample at your home using a temperature-controlled cold-chain system; no hospital visit is required, and the procedure complies with DHA home healthcare regulations. Our VIP mobile phlebotomy service is available daily from 8 AM to 11 PM.
3. Is this test covered by insurance and what documentation do I need?
We offer direct insurance verification via WhatsApp at +971 54 548 8731. You will need to provide your Emirates ID and insurance card. Our team will confirm approval and submit the pre-authorization request within two hours.
UAE Regulatory & Data Privacy Adherence
This test adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. All genetic data is classified as sensitive and is processed with the highest confidentiality and security measures.
Clinical & Logistical Metadata
| Test Name | TG Gene Thyroid Dyshormonogenesis Type 3 Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 21 calendar days |
| Sample Type / Matrix | Whole Blood (Peripheral) |
| Methodology Used | Targeted Next-Generation Sequencing (NGS) with Confirmatory Sanger Sequencing |
| ICD-10-CM Code | E07.1, Z13.29, Z14.8 |
| LOINC Code | 98137-4 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians