Test Price
2,800 AED✅ Home Collection Available
TFAP2B Gene Char Syndrome Genetic Test in UAE | DNA Labs UAE
Executive Summary & Core Metrics
- Diagnostic Accuracy: >99.9% analytical sensitivity for single nucleotide variants, indels, and mosaic mutations down to 5% variant allele frequency (VAF).
- Logistics Excellence: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM; sample integrity preserved for all ages.
- Clinical Guidance: Post-test tele-counselling with a consultant medical geneticist to interpret results within the complete clinical picture.
- Insurance Direct Billing: Eligibility verification via WhatsApp +971 54 548 8731; most UAE policies cover genetic diagnostics when referred by a DHA-licensed specialist.
Test Overview & Methodology
The TFAP2B NGS test screens the entire coding region and splice sites of the TFAP2B gene with 100% coverage of all exons, delivering definitive variant classification. Below is how our UAE-optimized service compares to the nearest alternative (single-gene Sanger sequencing).
| Feature | Our NGS Test (DNA Labs UAE) | Sanger Sequencing (Alternative) |
|---|---|---|
| Analytical Sensitivity | >99.9% for SNVs, indels, and mosaicism down to 5% VAF | ~99% for point mutations; poor detection of mosaicism <15% |
| Methodology | NGS with validated bioinformatics pipeline | Sanger capillary electrophoresis |
| Turnaround Time | 3–4 weeks (expedited options available) | 4–6 weeks |
| ISO Accreditation | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Often not accredited for genetic testing |
| Price | 2,800 AED (insurance direct billing supported) | 2,500–3,200 AED (typically upfront payment) |
Physician Insight & Safety Protocols
"As a consultant medical geneticist, I appreciate the weight a genetic result carries for a family. It is vital to interpret TFAP2B variants within the complete clinical picture, never as an isolated verdict. Our multidisciplinary team stands ready to guide you through every step, from pre-test counselling to post-test management."
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory & Medication Caution
⚠️ Do not discontinue any prescribed medication or alter treatment based solely on a genetic result without consulting your attending physician. This test does not replace clinical judgement.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients who have received a blood transfusion or allogeneic bone marrow transplant within the past 4 weeks may yield donor DNA; postpone collection.
- Exclusion: Non-clinical, non-validated use without physician referral is strictly against UAE healthcare regulations.
- Exclusion: Minors under 18 years without legal guardian consent; the legal guardian must be present during genetic counselling.
- ER Red Flag: If the patient experiences prolonged bleeding, severe pain, fainting, or signs of infection at the blood draw site, seek immediate medical attention.
- ER Red Flag: Any interpretation suggesting a pathogenic variant must be correlated clinically; do not consider a positive result as an emergency but schedule follow-up with a clinical geneticist promptly.
Patient FAQ & Clinical Guidance
1. What is the diagnostic value of the TFAP2B NGS test for Char syndrome?
This NGS test identifies pathogenic TFAP2B mutations in 95% of clinically diagnosed Char syndrome cases, including rare mosaic variants. The comprehensive analysis provides molecular confirmation essential for precise genetic counselling and family risk assessment.
2. How reliable is home phlebotomy for genetic testing, and is it safe for infants?
Our ISO-certified cold-chain home collection is performed by specialized paediatric phlebotomists, maintaining sample integrity identical to in-hospital draws, with a <1% sample rejection rate. For neonates and infants, we use a microcollection technique requiring only a few drops of blood on an FTA card.
3. Will my insurance cover this test, and what is the reimbursement process?
We directly verify your insurance eligibility before sample collection via WhatsApp (+971 54 548 8731), and most UAE policies cover genetic diagnostics when referred by a DHA-licensed paediatrician or neonatologist. Our billing team manages pre-approval and submits claims on your behalf.
UAE Regulatory & Data Privacy Adherence
This genetic test service complies fully with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – all genetic data encrypted and stored on servers within the UAE.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – secure digital handling of health information.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – patient consent and clinical safety protocols strictly enforced.
ISO 9001:2015 certified facility (Cert: INT/EGQ/2509DA/3139). DHA Facility License: 1143.
Clinical & Logistical Metadata
| Test Name | TFAP2B Gene Char Syndrome Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks (expedited options available) |
| Sample Type / Matrix | Peripheral whole blood (or FTA card for neonates) |
| Methodology Used | Next Generation Sequencing (NGS) with validated bioinformatics pipeline |
| ICD-10-CM Code | Q87.8 (Other specified congenital malformation syndromes) |
| LOINC Code | 81319-5 (TFAP2B gene full sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians