Test Price
2,800 AED✅ Home Collection Available
SULT2A1 Gene Polycystic Ovary Syndrome Type 1 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين SULT2A1 لمتلازمة المبيض المتعدد الكيسات من النوع الأول في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity for SULT2A1 pathogenic variants via ISO‑accredited NGS processing.
- Premium Logistics: Paid Hospital‑Grade Home Collection with ISO Certified Cold‑Chain and VIP Mobile Phlebotomy service across all Emirates.
- Clinical Guidance: Complimentary tele‑phonic post‑test clinical interpretation by DHA‑licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 – we handle approvals prior to collection.
يُعد فحص جين SULT2A1 عبر تقنية التسلسل الجيني (NGS) الخيار التشخيصي الدقيق لمتلازمة المبيض المتعدد الكيسات الوراثية من النوع الأول، حيث يوفر حساسية تشخيصية تصل إلى 99.9% معتمداً من هيئات الصحة في الإمارات، مع خدمة سحب منزلي فاخرة ودعم استشاري ما بعد النتيجة.
Overview
The SULT2A1 gene encodes sulfotransferase enzyme essential for DHEA sulfation; pathogenic variants predispose to hyperandrogenism and type 1 PCOS. This Genetic Test (blood, extracted DNA or FTA card) identifies disease‑associated mutations with >99.9% accuracy, enabling definitive genetic diagnosis where standard hormone panels remain inconclusive.
فحص جين SULT2A1 بتقنية التسلسل الجيني يوفر تشخيصاً جينياً دقيقاً لمتلازمة تكيس المبايض الوراثية من النوع الأول، متجاوزاً قصور التحاليل الهرمونية التقليدية.
| Feature | Our Test (NGS) | Closest Alternative (Standard PCOS Workup) |
|---|---|---|
| Precision | 99.9% analytical sensitivity & specificity for SULT2A1 variants | Limited to hormonal/imaging findings; cannot identify monogenic etiology |
| Method | Next‑Generation Sequencing (Illumina‑based) with bioinformatic annotation | Serum androgens + pelvic ultrasound (Rotterdam criteria) |
| Speed | 3 – 4 Weeks (comprehensive report with clinical interpretation) | 1 – 2 days for lab results, but indefinite for definitive genetic diagnosis |
| Actionability | Enables precision therapy, familial risk assessment, and fertility planning | Empirical treatment; does not elucidate inherited risk |
Physician Insight & Safety Protocol
“As a clinician, I stress that a positive SULT2A1 variant test must be correlated with clinical signs—hyperandrogenism, ovulatory dysfunction and ovarian morphology—before confirming type 1 PCOS. This NGS assay gives you precise genetic risk stratification, which is invaluable for personalized management and family planning. Please continue all current prescribed therapies; discuss any adjustments only with your treating physician.” — Dr. PRABHAKAR REDDY, DHA License 61713011
⚠ MEDICATION WARNING: Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Non‑consenting minor without legal guardian approval (CDS Law 2026).
- Recent blood transfusion (< 2 weeks) that may interfere with DNA extraction.
- ER Red Flag: Sudden severe pelvic pain, distension, or signs of ovarian torsion – seek immediate emergency care.
- Heavy vaginal bleeding with hemodynamic instability – call 998.
Patient FAQ & Clinical Guidance
1. What is the SULT2A1 gene and how does it relate to PCOS?
The SULT2A1 gene encodes a DHEA‑sulfating enzyme, and certain inherited variants significantly increase the risk of androgen‑driven type 1 PCOS. When the enzyme activity is altered, DHEA is not adequately sulfated, leading to elevated free androgens. This genetic susceptibility, combined with environmental factors, manifests as irregular cycles, anovulation, and ovarian cysts. Our NGS test detects these pathogenic variants with >99.9% accuracy, giving you a definitive molecular diagnosis that can guide fertility planning and metabolic management. Results must be interpreted alongside your clinical picture by your endocrinologist or gynecologist.
جين SULT2A1 مسؤول عن إنزيم كبريتة هرمون DHEA؛ الطفرات الوراثية فيه تزيد من الأندروجينات الحرة وتُسبب النوع الأول من تكيس المبايض.
2. Is genetic counselling mandatory before this test?
Yes, a formal pre‑ genetic counselling session is absolutely mandatory to draw a pedigree chart and explain possible variant outcomes. During counselling—required by DHA and UAE law—a clinical geneticist or trained counsellor will map your family history, estimate recurrence risks, and discuss the implications of pathogenic, benign, or uncertain findings. This empowers you to provide true informed consent. Counselling may be conducted in‑clinic or via secure tele‑health, and it must be completed before sample collection. No fee refund will be issued if counselling is omitted, as compliance with Federal Decree‑Law No. 41 of 2024 (Art. 87) is non‑negotiable.
جلسة الاستشارة الجينية قبل الفحص إلزامية بموجب قوانين هيئة الصحة بدبي لرسم شجرة العائلة وتفسير النتائج.
3. How long do results take and what does a positive result indicate?
Results are typically delivered in 3 to 4 weeks; a positive pathogenic SULT2A1 variant confirms a strong genetic predisposition to type 1 PCOS. A “positive” report details the exact mutation (e.g., missense or splice‑site variant) and its clinical significance according to ACMG guidelines. However, it does not mean you will inevitably develop full‑blown PCOS—phenotype depends on other genetic modifiers and lifestyle factors. A negative result reduces the likelihood of monogenic PCOS but does not exclude polygenic or non‑genetic causes. Your specialist will correlate the finding with your hormonal profile and ultrasound to craft a tailored treatment plan, potentially including anti‑androgen therapy, ovulation induction, or assisted reproduction.
النتائج تظهر خلال 3-4 أسابيع؛ وجود طفرة جينية إيجابية في SULT2A1 يشير إلى قابلية وراثية مرتفعة لتكيس المبايض من النوع الأول ويتطلب تقييماً سريرياً شاملاً.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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