Test Price
2,800 AED✅ Home Collection Available
STAT3 Gene Hyper‑IgE Syndrome Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑accredited NGS processing, aligned with international molecular pathology standards.
Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM.
Clinical Guidance: Complimentary post‑test telephonic clinical correlation discussion to interpret results in your personal health context.
Insurance & Billing: Direct verification and pre‑authorisation via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The STAT3 Gene Hyper‑IgE Syndrome NGS test comprehensively sequences the entire coding region of the STAT3 gene to detect pathogenic variants linked to autosomal dominant hyper‑IgE syndrome (AD‑HIES). This definitive molecular diagnosis guides lifelong immunologic, dermatologic, and orthopaedic management.
| Aspect | Our Test | Closest Alternative |
|---|---|---|
| Target | STAT3 full gene (exons + splice sites) | Whole Exome Sequencing (WES) |
| Detection Depth | >200× uniform coverage on STAT3 | ~50–80× average; STAT3 may be under‑covered |
| Turnaround Time | 3–4 Weeks | 6–10 Weeks |
| Cost | 2,800 AED | ~5,500–8,000 AED |
| Clinical Actionability | Focused, immediate for AD‑HIES | Broad incidental findings, genetic counselling burden |
Physician Insight & Safety Protocols
“A positive STAT3 variant confirms the clinical suspicion of hyper‑IgE syndrome and opens the door to targeted prophylaxis and monitoring. However, every result must be interpreted within the full clinical picture—genetics is a compass, not the whole map.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety Advisory & Precautionary Guidelines
⚠️ Medication & Safety Warning
Do not discontinue any prescribed immunosuppressive, antimicrobial, or other medication without explicit instruction from your treating physician. The test does not replace immediate care for acute infection or severe symptoms.
- If the patient experiences rapid spreading skin abscesses, high fever with chills, or signs of deep‑seated infection (e.g., pneumonia, osteomyelitis), seek emergency department evaluation immediately—do not wait for genetic test results.
- Active febrile illness may delay non‑urgent phlebotomy at phlebotomist’s discretion.
Exclusion Criteria & Consent Requirements
- Valid Specimen Types: Whole blood (EDTA), extracted DNA, or one drop of blood on FTA card.
- Exclusion Criteria (for home collection): Inability to provide informed consent; minors require legal guardian consent per Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Emergency Red Flags: Severe symptoms require immediate emergency department evaluation without waiting for genetic test results.
Patient FAQ & Clinical Guidance
1. What does the STAT3 gene test for Hyper‑IgE syndrome actually detect?
This detects single nucleotide variants, small insertions/deletions, and splice‑site mutations across all 24 coding exons of the STAT3 gene that cause autosomal dominant hyper‑IgE syndrome, enabling definitive confirmation of the clinical diagnosis.
2. Why does the turnaround time take 3–4 weeks?
The TAT includes DNA extraction, library preparation, NGS sequencing, bioinformatics alignment, variant calling against the human reference genome, clinical classification per ACMG guidelines, and a double‑blinded scientist review, ensuring every report meets 99.9% analytical sensitivity standards.
3. Can I use my insurance to cover the 2,800 AED fee?
Many UAE policies cover genetic testing when medically indicated; our team directly verifies your coverage via WhatsApp (+971 54 548 8731) and handles pre‑approval with your insurer before the blood collection appointment.
UAE Regulatory & Data Privacy Adherence
This clinical service complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) for all patient data processing and storage, and adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for digital health information governance. Clinical safety and patient consent are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability. The laboratory operates under DHA‑approved methodology (NGS, Illumina platform, GRCh38/hg38 alignment, clinically validated bioinformatics pipeline) and holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | STAT3 Gene Hyper‑IgE Syndrome NGS Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card blood spot |
| Methodology Used | Next‑Generation Sequencing (NGS) on Illumina platform, GRCh38/hg38 alignment, clinically validated bioinformatics pipeline |
| ICD‑10‑CM Code | D82.4, Z15.89, Z82.79 |
| LOINC Code | 101501-7 |
| DHA Facility License & Laboratory Address | License #1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians