Test Price
2,800 AED✅ Home Collection Available
STAT3 Gene Hyper‑IgE Syndrome Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل جين STAT3 لمتلازمة فرط IgE في الإمارات | ٢٨٠٠ درهم | معتمد من هيئة الصحة بدبي
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑accredited NGS processing, aligned with 2026 UAE molecular pathology standards.
Premium Logistics: Paid hospital‑grade home collection using ISO‑certified cold‑chain transport and VIP mobile phlebotomy (8 AM‑11 PM).
Clinical Guidance: Complimentary post‑test telephonic clinical correlation discussion to interpret results in your personal health context.
Insurance & Billing: Direct verification and pre‑authorisation via WhatsApp at +971 54 548 8731.
الفحص الجيني لجين STAT3 هو المعيار الذهبي لتشخيص متلازمة فرط الغلوبولين المناعي E (مرض جوب) الوراثي. نضمن دقة تصل إلى 99.9% باستخدام تقنيات التسلسل الجيني الفائقة وفق بروتوكولات هيئة الصحة بدبي (2026) مع حماية كاملة للبيانات طبقاً للمرسوم بقانون اتحادي رقم (41) لسنة 2024.
Test Overview
The STAT3 Gene Hyper‑IgE Syndrome NGS test comprehensively sequences the entire coding region of the STAT3 gene to detect pathogenic variants linked to autosomal dominant hyper‑IgE syndrome (AD‑HIES). يكشف التحليل الطفرات المسببة لمتلازمة فرط الغلوبولين المناعي E التي تتميز بالخراجات المتكررة والإكزيما وارتفاع IgE وتشوهات هيكلية. This definitive molecular diagnosis guides lifelong immunologic, dermatologic, and orthopaedic management.
| Aspect | Our Test | Closest Alternative |
|---|---|---|
| Target | STAT3 full gene (exons + splice sites) | Whole Exome Sequencing (WES) |
| Detection Depth | >200× uniform coverage on STAT3 | ~50–80× average; STAT3 may be under‑covered |
| Turnaround Time | 3–4 Weeks | 6–10 Weeks |
| Cost | 2,800 AED | ~5,500–8,000 AED |
| Clinical Actionability | Focused, immediate for AD‑HIES | Broad incidental findings, genetic counselling burden |
Physician Insight & Safety Protocol
“A positive STAT3 variant confirms the clinical suspicion of hyper‑IgE syndrome and opens the door to targeted prophylaxis and monitoring. However, every result must be interpreted within the full clinical picture—genetics is a compass, not the whole map.”
— Dr. Prabhakar Reddy, DHA License 61713011
⚠️ Medication & Safety Warning: Do not discontinue any prescribed immunosuppressive, antimicrobial, or other medication without explicit instruction from your treating physician. The test does not replace immediate care for acute infection or severe symptoms.
- Valid Specimen Types: Whole blood (EDTA), extracted DNA, or one drop of blood on FTA card.
- Exclusion Criteria (for home collection): Inability to provide informed consent (minors require legal guardian consent per CDS Law 2026); active febrile illness delaying non‑urgent phlebotomy at phlebotomist’s discretion.
- Emergency Red Flags: If the patient experiences rapid spreading skin abscesses, high fever with chills, or signs of deep‑seated infection (e.g., pneumonia, osteomyelitis), seek emergency department evaluation immediately—do not wait for genetic test results.
Compliant with Federal Decree‑Law No. 41 of 2024 (Art. 87) on genetic data consent; UAE PDPL (Personal Data Protection Law); and CDS Law 2026 governing minors’ genetic testing. Laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and operates under DHA/MOHAP‑approved methodology (NGS, Illumina platform, GRCh38/hg38 alignment, clinically validated bioinformatics pipeline). LOINC code: 101501-7. Core ICD‑10‑CM codes: D82.4 (Hyper‑IgE syndrome), Z15.89 (Genetic susceptibility to STAT3‑associated disease), Z82.79 (Family history of congenital anomalies).
Patient FAQ & Clinical Guidance
1. What does the STAT3 gene test for Hyper‑IgE syndrome actually detect?
This detects single nucleotide variants, small insertions/deletions, and splice‑site mutations across all 24 coding exons of the STAT3 gene that cause autosomal dominant hyper‑IgE syndrome, enabling definitive confirmation of the clinical diagnosis.
يكشف التحليل عن الطفرات في جميع إكسونات جين STAT3 المسؤولة عن متلازمة فرط IgE الجسمي السائد، مما يؤكد التشخيص السريري بدقة.
2. Why does the turnaround time take 3–4 weeks?
The TAT includes DNA extraction, library preparation, NGS sequencing, bioinformatics alignment, variant calling against the human reference genome, clinical classification per ACMG guidelines, and a double‑blinded scientist review, ensuring every report meets 99.9% analytical sensitivity standards.
تتطلب الفترة 3–4 أسابيع لاستخراج الحمض النووي، وإعداد المكتبات، والتسلسل، والتحليل المعلوماتي، والمراجعة السريرية المزدوجة وفق المعايير الدولية.
3. Can I use my insurance to cover the 2,800 AED fee?
Many UAE policies cover genetic testing when medically indicated; our team directly verifies your coverage via WhatsApp (+971 54 548 8731) and handles pre‑approval with your insurer before the blood collection appointment.
تغطي العديد من وثائق التأمين في الإمارات التحاليل الجينية عند وجود دواعٍ طبية، ويتولى فريقنا التحقق المباشر وإجراءات الموافقة المسبقة عبر الواتساب.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians