Test Price
2,800 AED✅ Home Collection Available
SS18L1 Gene Amyotrophic Lateral Sclerosis and CREST-Related Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Accurate, Confidential, UAE-Compliant Genetic Testing
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy and Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test analyzes the SS18L1 gene using Next-Generation Sequencing (NGS) to detect pathogenic variants associated with Amyotrophic Lateral Sclerosis (ALS) and CREST syndrome (limited systemic sclerosis). Designed for neurological and rheumatologic risk assessment, it empowers clinicians and patients with precise genomic insights, enabling early intervention and personalized care strategies in compliance with DHA genetic testing regulations.
| Feature | Our SS18L1 NGS Test | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Method | NGS (Full Gene Sequencing + CNV Detection) | Sanger Sequencing (Selected Exons Only) |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Sensitivity | >99.9% for single nucleotide variants, indels | Variable (~95%) for targeted regions |
| UAE Compliance | Fully DHA/MOHAP Licensed, ISO 9001:2015 | May lack local genetic counseling protocol |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist, I confirm that comprehensive genomic evaluation for ALS and CREST requires careful integration with family history, clinical phenotyping, and counseling. A detection in SS18L1 does not equate to inevitable disease manifestation; conversely, absence of a variant does not exclude all hereditary contributions. Always review results with your referring clinician before making medical decisions.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Prescription Continuity Advisory
Never stop or modify any prescribed treatment regimen without explicit guidance from your treating physician. Genetic test results are intended to inform, not replace, ongoing medical management.
Safety Exclusion Criteria & Emergency Red Flags
- Genetic testing for individuals under 18 years requires legal guardian consent and prior DHA-approved genetic counseling in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Patients with untreated psychiatric instability or limited capacity to understand genomic implications should postpone testing until appropriate psychosocial support is in place.
- If you experience acute neurological deterioration such as sudden muscle weakness, respiratory difficulty, or dysphagia, seek emergency care immediately without waiting for test results.
- A positive SS18L1 variant associated with ALS necessitates prompt referral to a specialized ALS clinic within 7 calendar days.
Patient FAQ & Clinical Guidance
1. What is the purpose of the SS18L1 genetic test, and who should consider it?
The SS18L1 NGS test detects inherited mutations linked to amyotrophic lateral sclerosis (ALS) and CREST syndrome, making it ideal for patients with early neurological or rheumatologic symptoms or a strong family history. A clinical genetic counselor can help you determine eligibility, especially if you have unexplained muscle twitching, Raynaud’s phenomenon, or esophageal dysmotility.
2. How is the sample collected, and is there any special preparation?
Sample collection is minimally invasive using a standard blood draw, a single drop of blood on an FTA card, or extracted DNA; no fasting is required and you may continue regular medications. Our VIP mobile phlebotomy service ensures a comfortable, cold-chain certified process anywhere in the UAE between 8 AM and 11 PM daily.
3. Are results confidential, and can I share them with my doctor?
All genetic data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and stored in encrypted ISO 9001:2015 systems; you will receive a DHA-validated report accessible only via a secure portal. You can share the results directly with your neurologist or rheumatologist, and our post-test teleconsultation clarifies findings to prevent misinterpretation.
UAE Regulatory & Data Privacy Adherence
Accreditation & Compliance: ISO 9001:2015 Certified (Certificate No. INT/EGQ/2509DA/3139). Fully licensed by the Dubai Health Authority (DHA) under Facility License Number 1143.
Data Protection: All patient data handled in strict accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Book Your Test: Call or WhatsApp +971 54 548 8731 for immediate scheduling or insurance verification.
Home Collection Hours: 8:00 AM – 11:00 PM, 7 days a week.
Clinical & Logistical Metadata
| Test Name | SS18L1 Gene Sequencing for Amyotrophic Lateral Sclerosis and CREST Syndrome |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral), Saliva, or Extracted DNA |
| Methodology Used | Next-Generation Sequencing (NGS) with CNV Detection |
| ICD-10-CM Code | G12.21, M34.1 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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