Test Price
2,800 AED✅ Home Collection Available
SMC3 Gene (Cornelia de Lange Syndrome Type 3) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل الجين SMC3 (متلازمة كورنيليا دي لانج النوع 3) بتقنية التسلسل الجيني NGS في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
This ISO 9001:2015 certified Next-Generation Sequencing (NGS) test delivers 99.9% diagnostic sensitivity for detecting pathogenic variants in the SMC3 gene, the established cause of Cornelia de Lange syndrome type 3. We provide a complete DHA‑compliant package: hospital-grade home collection (8 AM–11 PM) with certified cold-chain logistics, rapid 3‑4 week turnaround, and complimentary telephonic post-test clinical guidance by our genetic counsellors. Direct insurance billing verification is available via WhatsApp at +971 54 548 8731.
فحص جيني معتمد بتقنية التسلسل من الجيل التالي بدقة تشخيصية تصل إلى 99.9% للكشف عن طفرات جين SMC3 المسببة لمتلازمة كورنيليا دي لانج النوع الثالث. تشمل الخدمة سحب عينات منزلية على مستوى المستشفيات بسلسلة تبريد معتمدة، وإصدار النتائج خلال 3–4 أسابيع، واستشارة سريرية مجانية بعد الفحص. التحقق من التغطية التأمينية متاح عبر واتساب.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity – ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection with Certified Cold-Chain Transport.
- Clinical Guidance: Telephonic Post-Test Interpretation by a DHA-Licensed Professional.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
The SMC3 NGS test sequences the entire coding region of the SMC3 gene to detect mutations responsible for Cornelia de Lange syndrome type 3, a rare genetic disorder characterized by distinctive facial features, growth retardation, and limb abnormalities. يقوم هذا الفحص بتحليل كامل لجين SMC3 للكشف عن الطفرات المسببة لمتلازمة كورنيليا دي لانج النوع الثالث.
| Feature | Our Test (NGS Full Gene) | Closest Alternative (Sanger Panel) |
|---|---|---|
| Precision | 99.9% sensitivity, detects SNVs & CNVs | ~95% sensitivity, misses structural variants |
| Method | Next-Generation Sequencing (Illumina NovaSeq) | Sanger sequencing of selected exons |
| Speed | 3–4 Weeks | 4–6 Weeks |
Physician Insight & Safety Protocol
“As a DHA-licensed geneticist, I want to stress that this SMC3 NGS test provides highly reliable molecular confirmation, but clinical correlation with a thorough physical examination by a Clinical Geneticist or Pediatrician is essential. A negative result does not exclude the diagnosis if clinical suspicion is high, and a positive result should guide personalized management and family counselling. Always discuss the implications with a qualified genetic counsellor.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠️ Medication Warning:
Do not discontinue any prescribed medication or alter your treatment plan without first consulting your treating physician. This genetic test is diagnostic, not prescriptive.
Exclusion Criteria & Safety Red Flags
- Individuals under 18 years of age require written guardian consent per 2026 Child Digital Safety (CDS) Law.
- Patients currently undergoing chemotherapy or having received a blood transfusion within 2 weeks should postpone the blood draw; please discuss with your physician.
- If you experience acute respiratory distress, uncontrolled bleeding, or sudden neurological changes, seek emergency medical care immediately – do not wait for test results.
UAE Regulatory Compliance
- Federal Decree-Law No. 41 of 2024 (Art. 87) – Medical Liability & Patient Safety.
- Child Digital Safety (CDS) Law 2026 – Minors require explicit guardian consent.
- UAE Personal Data Protection Law (PDPL) – All genetic data processed and stored within UAE borders.
- ISO 9001:2015 Certification: INT/EGQ/2509DA/3139.
Patient FAQ & Clinical Guidance
Q1: Who should consider the SMC3 Genetic Test?
The test is recommended for individuals with clinical signs of Cornelia de Lange syndrome type 3, such as distinctive craniofacial dysmorphism, prenatal and postnatal growth retardation, upper limb malformations, and developmental delay, when a definitive molecular diagnosis is needed for management and family planning.
يُوصى بالفحص للأفراد الذين تظهر عليهم علامات سريرية لمتلازمة كورنيليا دي لانج مثل تشوهات الوجه المميزة وتأخر النمو وعيوب الأطراف، لتأكيد التشخيص الجيني بدقة.
Q2: What does the home collection service include and how is the sample transported?
A DHA-certified phlebotomist visits your home, collects a small blood sample in a special EDTA tube (or a dried blood spot if preferred), and immediately places it in a validated cold-chain container for transport to our ISO-accredited lab, ensuring sample integrity throughout.
يقوم فني مختص مرخص من هيئة الصحة بدبي بزيارة منزلية لسحب عينة دم وريدية تُحفظ في حاوية تبريد معتمدة وتُنقل مباشرة إلى المختبر، مما يضمن سلامة العينة.
Q3: How long does it take to receive the result and what will it tell me?
Results are reported within 3–4 weeks and will indicate whether a disease-causing variant was detected in the SMC3 gene; a detailed interpretation letter from our clinical geneticist is included, with a post- tele-consultation to discuss implications.
تُصدر النتائج خلال 3–4 أسابيع وتوضح ما إذا تم اكتشاف طفرة ممرضة في جين SMC3، مع تقرير تفسيري واستشارة هاتفية مجانية من أخصائي الوراثة السريرية.
This page is for informational purposes and does not replace professional medical advice. For enquiries, contact us on WhatsApp at +971 54 548 8731. UAE Facility License: 9834453. ISO 9001:2015 (INT/EGQ/2509DA/3139). All services comply with DHA/MOHAP standards.
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التحقق من التغطية التأمينية
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians