Test Price
2,800 AED✅ Home Collection Available
SLCO1B1 Gene Rotor‑type Hyperbilirubinemia Genetic Test in UAE | 2800 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
- Test Price: 2,800 AED
- Turnaround Time: 3–4 weeks from sample receipt
- Sample Type: Whole blood (EDTA), dried blood spot (FTA card), or extracted DNA
- Methodology: Illumina® Next‑Generation Sequencing (NGS) with full gene sequencing
- Diagnostic Sensitivity: 99.9% for SLCO1B1 pathogenic variants
- Clinical Use: Confirm hereditary Rotor syndrome, differentiate from other conjugated hyperbilirubinemias
- Home Collection: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily 8 AM–11 PM
Test Overview & Methodology
The SLCO1B1 gene Rotor‑type hyperbilirubinemia genetic test uses Next‑Generation Sequencing to detect single nucleotide variants and small insertions/deletions in the SLCO1B1 gene. Pathogenic variants in this gene cause Rotor syndrome, a benign form of conjugated hyperbilirubinemia that does not require treatment. Genetic confirmation eliminates the need for invasive liver biopsy or repeated biochemical workups.
| Feature | Our Genetic Test | Traditional Biochemical Workup |
|---|---|---|
| Precision | 99.9% analytical sensitivity – identifies single nucleotide variants and small indels | Indirect (coproporphyrin isomers, TBG HIDA scan) – may miss atypical presentations |
| Method | Illumina® Next‑Generation Sequencing with full gene sequencing | Serum bilirubin fractionation, urine porphyrins, imaging |
| Turnaround Time | 3–4 weeks (DNA extracted from blood/FTA card) | 2–5 days but often requires multiple clinic visits and repeat tests |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I advise that Rotor syndrome is a benign inherited condition. Genetic testing provides definitive diagnosis and spares patients from unnecessary invasive procedures. However, always correlate genetic results with the full clinical picture and consult a specialist before making any health decisions. Never alter or discontinue any prescribed medication without direct medical advice.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Safety Advisory
Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Altering your treatment plan based solely on genetic test results can be dangerous. This test does not replace clinical management.
Exclusion Criteria & Emergency Red Flags
- Do not use for asymptomatic minors without legal guardian consent (in accordance with UAE Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Not to replace emergency liver function assessment in acute fulminant hepatitis or unexplained sudden jaundice.
- Recent blood transfusion (<2 weeks) may cause circulating donor DNA interference – postpone collection until after 2 weeks.
- ER Red Flags: New‑onset jaundice with severe abdominal pain, confusion, or bleeding – go to the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What does this NGS test detect?
It identifies disease‑causing mutations in the SLCO1B1 gene with 99.9% sensitivity, providing a definitive molecular diagnosis of Rotor‑type hyperbilirubinemia. This avoids the need for liver biopsy or repeated blood tests.
2. How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample receipt. A detailed clinical report is provided, including interpretation of detected variants.
3. Can I use a finger‑prick blood drop on an FTA card?
Yes, a single drop of blood on an FTA card is a fully validated sample type for this test. Our laboratory routinely extracts DNA from FTA cards for NGS analysis.
4. Does insurance cover the test cost of 2,800 AED?
We verify insurance coverage directly via WhatsApp (+971 54 548 8731) before collection. Flexible payment options are available for uninsured patients.
UAE Regulatory & Data Privacy Adherence
Your Data & Safety Are Protected
This genetic test is performed in full compliance with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring strict confidentiality of your genetic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – regulating digital health records and telemedicine.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – governing informed consent and safe practice.
- DHA standards under Facility License No. 1143, Dubai Healthcare City.
Your data is used solely for diagnostic purposes and is never shared without your explicit consent.
Clinical & Logistical Metadata
| Test Name | SLCO1B1 Gene Rotor‑type Hyperbilirubinemia Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), dried blood spot (FTA card), or extracted DNA (≥200 ng) |
| Methodology Used | Illumina® Next‑Generation Sequencing (NGS) – full gene sequencing |
| ICD-10-CM Code | E80.6 (Other disorders of bilirubin metabolism) |
| LOINC Code | 81247-9 (SLCO1B1 gene mutation analysis) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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