Test Price
2,800 AEDโ Home Collection Available
SLC4A5 Gene (Renal Tubular Acidosis) โ Genetic Test in UAE
Accuracy: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing. Home Collection: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM). Clinical Guidance: Complimentary Telephonic Post-Test Clinical Correlation by DHA-Licensed Physicians. Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Executive Summary & Core Metrics
Price
2,800 AED
Turnaround Time
3โ4 Weeks
Sample Type
Peripheral Whole Blood
Test Overview & Methodology
This SLC4A5 gene test uses Next-Generation Sequencing to identify pathogenic variants causing proximal renal tubular acidosis with ocular anomalies. The assay provides definitive molecular confirmation for individuals presenting with metabolic acidosis, growth delay, and ophthalmologic findings, enabling precise genetic counseling and early intervention.
| Our NGS Genetic Test | Standard Biochemical RTA Panel |
|---|---|
| Precision: NGS with 99.9% analytical sensitivity and full gene coverage | Indirect functional tests (urine pH, serum bicarbonate) with lower specificity |
| Method: Next Generation Sequencing detects single nucleotide variants, indels, and splice-site mutations | Limited to biochemical surrogates without molecular confirmation |
| Turnaround: 3โ4 Weeks for comprehensive analysis and clinical correlation | Same-day results but non-definitive for genetic etiology |
Physician Insight & Safety Protocols
โLina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403) emphasizes: A positive SLC4A5 variant confirms genetic predisposition to proximal renal tubular acidosis but must be interpreted alongside renal function tests, metabolic panels, and ophthalmologic assessment. Not all carriers express the full phenotype; longitudinal clinical monitoring and family cascade screening remain essential. Always consult a genetic specialist before making treatment decisions based on this result.โ
Advisory: Medication & Treatment Guidance
Do not discontinue, adjust, or initiate any prescribed alkali therapy, potassium supplementation, or other renal medications without direct supervision from your treating nephrologist or metabolic specialist. Abrupt changes in therapy may precipitate severe metabolic decompensation requiring emergency intervention.
Safety Exclusion Criteria & Emergency Red Flags
- Active infection or recent blood transfusion (within the last 4 weeks) may compromise DNA extraction quality and assay accuracy.
- Known latex allergy requires use of a latex-free collection kit; notify the phlebotomy team in advance.
Seek Emergency Care Immediately If:
- Severe metabolic acidosis with confusion, rapid deep breathing (Kussmaul respirations), or cardiac arrhythmia.
- Persistent vomiting, lethargy, or dehydration in a child with known or suspected renal tubular acidosis.
Patient FAQ & Clinical Guidance
1. What is the SLC4A5 gene test and why is it ordered?
This NGS-based genetic test detects disease-causing mutations in the SLC4A5 gene, which is linked to proximal renal tubular acidosis with ocular abnormalities. It is ordered for individuals with unexplained metabolic acidosis, failure to thrive, nephrocalcinosis, or family history of renal tubular disorders, guiding accurate diagnosis, prognosis, and familial risk assessment.
2. How is the sample collected and what is the turnaround time?
A standard peripheral whole blood sample is collected via VIP mobile phlebotomy at your home or at our Dubai Healthcare City facility. For remote patients, an FTA card or extracted DNA sample may be accepted. Results are delivered within 3โ4 weeks from sample receipt, including a comprehensive molecular report and clinical correlation.
3. Is this test covered by insurance in the UAE?
Yes, we verify direct billing coverage for most UAE health insurance plans. Send your policy details via WhatsApp to +971 54 548 8731 for a rapid pre-authorization check. Self-pay options are also available at 2,800 AED inclusive of phlebotomy and genetic counseling.
4. Do I need genetic counseling before or after the test?
Yes, pre-test genetic counseling is mandatory to draw a pedigree chart and discuss implications of possible results. Post-test telephonic counseling by our DHA-licensed clinical geneticist is provided at no additional charge to help interpret the report and guide next steps.
UAE Regulatory & Data Privacy Adherence
Legal & Compliance Framework
- This genetic test is performed under DHA Facility License Number 1143 and adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all patient genetic data processing and storage.
- Health information handling complies with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring secure electronic medical records and telemedicine workflows.
- Clinical laboratory operations are ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139), guaranteeing rigorous quality management across pre-analytical, analytical, and post-analytical phases.
- All specimen collection and patient safety protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring informed consent and clinical accountability.
Clinical & Logistical Metadata
| Test Name | SLC4A5 Gene (Renal Tubular Acidosis) โ Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood or Buccal Swab |
| Methodology Used | Next Generation Sequencing (NGS) โ Full Gene Coverage |
| ICD-10-CM Code | E72.09 |
| LOINC Code | 81245-8 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians