Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3โ4 Weeks
SLC26A6 Gene Hyperoxaluria Genetic Test in UAE | AED 2800 | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189 Accredited NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (available daily 8 AM โ 11 PM).
- Clinical Guidance: Telephonic post-test result interpretation from a Consultant Medical Geneticist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This NGS-based genetic test analyzes the SLC26A6 gene for mutations linked to hyperoxaluria, providing definitive diagnosis and risk stratification for metabolic stone disease. It is recommended for patients with recurrent calcium oxalate kidney stones and for family screening. The test uses next-generation sequencing (NGS) to interrogate all exons and splice sites of the gene, offering superior sensitivity and coverage compared to traditional Sanger sequencing.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Target Gene Coverage | Full SLC26A6 gene, all exons & splice sites | Single exon/amplicon per run |
| Analytical Sensitivity | 99.9% | ~99.5% (varies by region) |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks (for full gene) |
| Cost Efficiency per Gene | AED 2800 (all-inclusive) | Often higher due to multiple reactions |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
โInterpreting SLC26A6 variants requires correlation with urinary oxalate and glycolate levels, as well as family history. A pathogenic mutation confirms susceptibility to primary hyperoxaluria type 2, but a negative result does not exclude other genetic or acquired causes. Referral to a nephrologist and metabolic bone specialist is essential for personalized management.โ
Advisory Notice
โ ๏ธ Important: Do not discontinue prescribed medication without consulting your doctor. Genetic results should guide, not replace, clinical management.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria:
- Pregnancy โ requires special clearance and genetic counselling prior to testing.
- Minors (<18 years) โ mandatory parental consent per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Patients on dialysis โ need referring physicianโs written approval.
Seek Emergency Care if:
- Sudden severe flank or abdominal pain
- Visible blood in urine (hematuria)
- Marked decrease in urine output
- Unexplained vision changes or skin ulcers (signs of systemic oxalosis)
Patient FAQ & Clinical Guidance
1. What does a positive SLC26A6 mutation mean for my health?
A positive result indicates an increased risk for hyperoxaluria and calcium oxalate kidney stones, but not everyone develops symptoms. Clinical follow-up with a nephrologist and periodic imaging are recommended. Family members may also consider testing.
2. How is the genetic sample collected?
Sample collection involves a simple blood draw or a painless cheek swab on an FTA card, performed at your home by a licensed phlebotomist. No special fasting or diet is required. The sample is then transported in a validated cold chain.
3. Will insurance cover the cost of this genetic test?
Insurance coverage varies; our team provides direct billing verification via WhatsApp to check your policy benefits. Many UAE policies partially cover genetic testing when medically indicated, and we assist with pre-authorisation.
UAE Regulatory & Data Privacy Adherence
Secure & Compliant Testing
DNA Labs UAE operates under DHA Facility License No. 1143 (Premises 105, Floor 1, Building 33, Dubai Healthcare City). All genetic data handling complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and medical liability adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Your results are encrypted and never shared without explicit authorisation.
Clinical & Logistical Metadata
| Test Name | SLC26A6 Gene Hyperoxaluria Genetic Test |
| Price (AED) | 2800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or buccal swab (FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) โ full gene sequencing with splice site analysis |
| ICD-10-CM Code | E74.81 (Primary hyperoxaluria) |
| LOINC Code | 93931-6 (SLC26A6 gene targeted mutation analysis) |
| DHA Facility License & Address | License No. 1143 ยท Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
Preparation Required
["No special fasting or diet is required."]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians