Test Price
2,800 AED✅ Home Collection Available
SLC22A12 Gene Hypouricemia, Renal Type 1 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Free telephonic post-test clinical interpretation support.
Insurance: Direct billing verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
This advanced genetic test sequences the entire SLC22A12 gene using Next‑Generation Sequencing (NGS) to detect pathogenic mutations causing hereditary renal hypouricemia type 1. It is recommended for individuals with persistently low serum uric acid, a positive family history, or at‑risk athletes who engage in high‑intensity physical activity.
| Feature | Our Test (NGS) | Sanger Sequencing (Alternative) |
|---|---|---|
| Methodology | Next‑Generation Sequencing (full gene coverage) | Targeted Sanger analysis (exon‑by‑exon, limited variants) |
| Diagnostic Sensitivity | >99.9% for known mutations | ~95% (may miss deep intronic variants) |
| Turnaround Time | 3‑4 weeks | 4‑5 weeks |
| Price | 2800 AED | ~3500 AED (varies by lab) |
Physician Insight & Safety Protocols
“This NGS panel for the SLC22A12 gene provides a comprehensive molecular view of hereditary renal hypouricemia type 1. Identifying a pathogenic mutation confirms the genetic basis of low serum uric acid and guides personalized management to prevent exercise‑induced acute kidney injury. I strongly recommend that patients discuss findings with their nephrologist for tailored surveillance and family cascade screening.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory & Pre‑Test Requirements
⚠️ Medication Advisory
Do not discontinue any prescribed medication (e.g., uric‑acid‑lowering drugs) without consulting your attending physician.
✅ Exclusion Criteria & Pre‑Test Requirements:
- No specific contraindications for sample collection; however, a genetic counselling session must be completed to draw a detailed pedigree and clinical history.
- Samples accepted: whole blood, extracted DNA, or one drop of blood on FTA card.
🚨 ER Red Flags (Seek emergency care if present):
- Sudden severe flank pain, hematuria (blood in urine), or drastically reduced urine output — potential acute kidney injury in undiagnosed renal hypouricemia.
Patient FAQ & Clinical Guidance
1. What does the SLC22A12 gene test detect?
The SLC22A12 gene test detects inherited mutations causing renal hypouricemia type 1, a disorder marked by abnormally low blood uric acid levels and increased risk of exercise‑induced kidney injury.
2. Who should consider this genetic test?
Individuals with persistently low serum uric acid (<2.0 mg/dL), a family history of kidney stones or hypouricemia, and high‑intensity athletes should consider screening for SLC22A12 mutations.
3. How is the test performed and what is the turnaround time?
A home‑based phlebotomy collects a small blood sample or FTA card spot; our ISO‑certified NGS lab delivers results in 3–4 weeks with optional telephonic clinical guidance.
4. Will insurance cover this genetic test?
We offer direct billing verification via WhatsApp at +971 54 548 8731. Coverage depends on your specific insurance plan and medical necessity criteria.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection
All genetic testing and personal data handling at DNA Labs UAE strictly comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic information is encrypted, access‑controlled, and processed solely for diagnostic purposes.
Clinical & Logistical Metadata
| Test Name | SLC22A12 Gene Hypouricemia, Renal Type 1 Genetic Test (NGS) |
| Price (AED) | 2800 AED |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card blood spot |
| Methodology Used | Next‑Generation Sequencing (NGS) — full SLC22A12 gene coverage |
| ICD-10-CM Code | E79.8 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians