Also known as: SIGMAR1 Gene Amyotrophic Lateral Sclerosis Type 16 Genetic Test (NGS)
Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3โ4 Weeks
SIGMAR1 Gene ALS Type 16 Genetic Test in UAE | 2800 AED | DHA Approved
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
Clinical Guidance: Telephonic Post-Test Clinical Guidance with result interpretation by a DHA-licensed Consultant Medical Geneticist.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The SIGMAR1 Gene Amyotrophic Lateral Sclerosis Type 16 Genetic Test sequences the entire SIGMAR1 gene to detect pathogenic variants linked to ALS16, a rare inherited motor neuron disease. This next-generation sequencing (NGS) assay delivers definitive molecular confirmation within 3โ4 weeks, enabling precise diagnosis, family risk assessment, and personalised management under DHA-approved protocols.
| Feature | Our NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | >99.9% analytical sensitivity for entire gene | ~95% sensitivity, may miss deep intronic variants |
| Methodology | Massively parallel NGS + bioinformatic variant calling | Capillary electrophoresis-based Sanger sequencing |
| Turnaround Time | 3โ4 Weeks | 5โ7 Weeks |
| Sample Requirements | Whole Blood, Extracted DNA, or FTA Card | Whole Blood or Extracted DNA |
| Cost | 2800 AED | 2500โ3200 AED (variable) |
Physician Insight & Safety Protocols
โAs a DHA-licensed Consultant Medical Geneticist, I emphasise that this test provides a molecular diagnosis for ALS type 16, but results must be interpreted alongside full clinical evaluation and family history. A positive result does not guarantee disease onset, nor does a negative result exclude other forms of ALS. Pre- and post-test genetic counselling is mandatory to ensure informed decision-making and psychological readiness.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory & Pre-Test Requirements
Exclusion Criteria & Emergency Red Flags
- Individuals unable to provide informed consent, including minors lacking legal guardian authorization (per UAE Personal Data Protection Law).
- Presence of acute intercurrent illness requiring urgent non-genetic medical intervention.
- Incomplete pre-test genetic counselling session (mandatory pedigree chart and family history documentation).
ER Red Flags: Seek immediate emergency care if you experience sudden severe muscle weakness, respiratory distress, difficulty swallowing with choking, or rapid progression of limb paralysis โ regardless of test status.
Patient FAQ & Clinical Guidance
1. What does the SIGMAR1 genetic test reveal for ALS type 16?
Our NGS test identifies disease-causing variants in the SIGMAR1 gene that confirm a molecular diagnosis of ALS type 16, providing clarity for treatment planning and family risk assessment. Results are always accompanied by a genetic counselling session.
2. How is the test performed and what is the turnaround time?
A sample of whole blood, extracted DNA, or a single drop on an FTA card is collected at your home by a certified phlebotomist via VIP Mobile Phlebotomy, then analysed using next-generation sequencing with final results delivered in 3โ4 weeks.
3. What is the cost and can I use insurance?
The test is priced at 2800 AED with direct billing verification available through WhatsApp at +971 54 548 8731. We check your insurance eligibility instantly to minimise out-of-pocket payment.
UAE Regulatory & Data Privacy Adherence
Compliance Framework
This genetic test is conducted in full compliance with UAE federal laws governing medical data and genetic testing: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) ensures your genetic information is processed, stored, and transmitted with the highest security standards. Federal Law No. 2 of 2019 concerning the Use of Information and Communication Technology in Health Fields governs the secure handling of electronic health records. Clinical safety and informed consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE holds DHA Facility License No. 1143, ensuring all testing meets Dubai Healthcare City standards.
Clinical & Logistical Metadata
| Test Name | SIGMAR1 Gene Amyotrophic Lateral Sclerosis Type 16 Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) โ Whole Gene Sequencing |
| ICD-10-CM Code | G12.21 (Amyotrophic lateral sclerosis) โ for ALS16 |
| LOINC Code | 94436-0 (Genetics overall NGS sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
Preparation Required
["No specific fasting required", "Inform lab of any medications"]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians