Test Price
2,800 AED✅ Home Collection Available
SFTPB Gene Surfactant Metabolism Dysfunction Type 1 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين SFTPB لاضطراب استقلاب العامل السطحي من النوع الأول في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Certified NGS processing.
Premium Logistics: Hospital-Grade Home Collection with ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy.
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
The SFTPB Genetic Test screens for pathogenic variants in the SFTPB gene, the principal cause of surfactant metabolism dysfunction type 1 – a life-threatening neonatal lung disease. This test utilizes Next Generation Sequencing to deliver comprehensive coverage and detect even low-level mosaic mutations, ensuring early diagnosis and targeted clinical management.
| Feature | Our Test (SFTPB NGS) | Sanger Sequencing (Single-Gene) |
|---|---|---|
| Precision / Analytical Sensitivity | >99.9% (detects mosaic variants ≤5%) | ~95% (may miss low-level mosaicism) |
| Methodology | Next Generation Sequencing (NGS) | Sanger Sequencing |
| Turnaround Time | 3 to 4 Weeks | 3 to 4 Weeks |
| Price (AED) | 2800 | ~2000 (limited comprehensive analysis) |
Pre-Test Information & Genetic Counselling
A clinical history of the patient and a genetic counselling session to construct a detailed pedigree chart of family members affected by surfactant metabolism dysfunction type 1 are mandatory prior to sample collection. This ensures accurate risk assessment and appropriate variant interpretation.
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA License: 61713011): As a clinical pathologist, I emphasize that this NGS test provides comprehensive analysis of the SFTPB gene, but results must be correlated with clinical presentation, imaging findings, and family history. A negative result does not exclude all genetic etiologies of surfactant dysfunction, and a positive result demands immediate multidisciplinary evaluation. I strongly recommend that all patients discuss their results with a pediatric pulmonologist and a clinical geneticist to formulate a personalized care plan.
⚠️ Medication Warning: Do not discontinue any prescribed medication without consulting your treating physician.
Exclusion Criteria & Emergency Red Flags
- Inability or unwillingness to undergo pre-test genetic counselling.
- Hemolyzed, clotted, or insufficient sample volume – recollection will be required at no extra fee.
- Minors (<18 years) must have parental consent in compliance with UAE CDS Law 2026.
- ER Red Flags: Acute respiratory distress, cyanosis, grunting, nasal flaring, severe retractions, apnea, failure to thrive, or any sign of impending respiratory failure. Seek immediate emergency medical attention.
Patient FAQ & Clinical Guidance
1. What is the SFTPB NGS test used for?
Direct Answer: The SFTPB NGS test detects pathogenic mutations in the surfactant protein B gene to diagnose or rule out surfactant metabolism dysfunction type 1, a severe neonatal respiratory disorder.
Surfactant dysfunction type 1 leads to life-threatening respiratory failure in newborns. Early identification of SFTPB variants enables timely management, including potential lung transplantation or supportive care. The test is recommended for infants with unexplained respiratory distress, family history of the disease, or for carrier screening in at-risk families.
ما هو استخدام تحليل جين SFTPB؟
يكشف تحليل الجين SFTPB عن الطفرات الممرضة في جين البروتين الفاعل بالسطح الرئوي B لتشخيص أو استبعاد خلل استقلاب العامل السطحي من النوع الأول، وهو اضطراب تنفسي وخيم يصيب حديثي الولادة.
2. How is the sample collected for this test?
Direct Answer: A small blood sample, extracted DNA, or a single drop of blood on a specialized FTA card is collected by a certified phlebotomist in the comfort of your home.
Our premium home collection service operates from 8 AM to 11 PM and uses cold-chain logistics to preserve DNA integrity. You do not need to visit a lab; the entire process is rapid, minimally invasive, and compliant with UAE healthcare regulations.
كيف يتم جمع العينة لهذا التحليل؟
يتم جمع عينة دم صغيرة، أو الحمض النووي المستخلص، أو قطرة دم واحدة على بطاقة FTA متخصصة بواسطة فني معتمد في منزلك، مع الحفاظ على سلسلة التبريد.
3. What does a positive SFTPB result mean?
Direct Answer: A positive result confirms the presence of a disease-causing variant in the SFTPB gene, indicating a high probability of developing surfactant deficiency that requires immediate specialist evaluation.
A positive should always be interpreted together with clinical symptoms and family history. It may guide therapy options, eligibility for clinical trials, or early referral for lung transplantation. Genetic counseling will explain inheritance patterns (autosomal recessive) and implications for future pregnancies.
ماذا تعني النتيجة الإيجابية لتحليل SFTPB؟
تؤكد النتيجة الإيجابية وجود طفرة ممرضة في جين SFTPB، مما يشير إلى احتمال كبير للإصابة بنقص العامل السطحي الرئوي، ويتطلب تقييماً فورياً من قبل طبيب متخصص.
Legal & Regulatory Compliance: Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), UAE PDPL (Data Privacy).
Accreditation: ISO 9001:2015 Certified – Cert: INT/EGQ/2509DA/3139. Facility License: 9834453.
For Insurance verification, home collection booking, or urgent clinical queries, reach us on WhatsApp +971 54 548 8731.
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