Test Price
2,800 AED✅ Home Collection Available
SETD5 Gene Genetic Test for Autosomal Dominant Intellectual Disability Type 23 (MRD23) in UAE | AED 2800 | 2026 DHA Guidelines
تحليل جين SETD5 للإعاقة الذهنية الصبغية السائدة نوع 23 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – Clinical & Regulatory Assurance
ملخص تنفيذي: يضمن هذا التحليل الجيني المتقدم لجين SETD5 دقة تشخيصية بنسبة 99.9% وفق معايير هيئة الصحة بدبي لعام 2026، مع خدمة سحب منزلي عالي الجودة، وإرشاد طبي بعد الفحص، وتحقق مباشر من التأمين عبر واتساب.
Key Trust Signals:
- Diagnostic Sensitivity: 99.9% via ISO 9001:2015 Certified NGS (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital-Grade Home Collection (8 AM–11 PM), cold-chain transport.
- Post-Test Guidance: Telephonic clinical interpretation by a DHA-licensed physician.
- Insurance Support: Direct billing verification via WhatsApp at +971 54 548 8731.
Overview of SETD5 Gene Testing for Autosomal Dominant Intellectual Disability
The SETD5 gene sequencing test uses Next-Generation Sequencing (NGS) to detect pathogenic variants in the SETD5 gene, which cause autosomal dominant intellectual disability type 23 (previously termed mental retardation, autosomal dominant type 23). A pre-test genetic counselling session is required to draw a pedigree chart of affected family members. يستخدم هذا الفحص تقنية التسلسل الجيني المتقدم (NGS) للتعرف على الطفرات المسببة للإعاقة الذهنية النوع 23.
| Feature | Our SETD5 NGS Test | Closest Alternative (Exome Sequencing) |
|---|---|---|
| Precision | Single-gene full coding region + flanking introns; >99.9% analytical sensitivity | Whole-exome coverage may miss deep intronic variants |
| Methodology | NGS with Sanger confirmation of pathogenic variants | Exome capture + NGS, often without reflex confirmation |
| Turnaround Time | 3–4 weeks | 8–12 weeks |
Medical Coding & 2026 Standards
ICD-10-CM: F79 (Intellectual disability, unspecified) | Z14.8 (Genetic susceptibility to other disease) | Z13.79 (Encounter for screening for genetic and chromosomal anomalies)
LOINC: 81247-9 (DNA sequencing analysis)
Methodology: Next-Generation Sequencing (NGS) as per DHA/MOHAP Standard Nomenclature
Physician Insight & Safety Protocol
A Note from Dr. PRABHAKAR REDDY, DHA License: 61713011
"As a clinical neurologist, I emphasize that a positive SETD5 variant must be interpreted in the context of the patient’s full clinical picture and family history. This test is a powerful diagnostic tool, yet it does not replace comprehensive neurodevelopmental assessment. I am available for telephonic post-test guidance to help you and your family understand the implications."
Critical Medication Warning
Do not discontinue any prescribed antiepileptic, antipsychotic, or other medications without consulting your doctor. Abrupt withdrawal can cause serious health risks.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients with acute illness or those unable to provide informed consent. Minors require parental/guardian consent as per UAE CDS Law 2026.
- Red Flags: If the individual experiences new-onset seizures, severe behavioral regression, or loss of previously acquired skills, seek immediate emergency medical attention at a DHA-licensed facility.
- Sample rejection: Hemolyzed or clotted blood; insufficient DNA quantity.
Patient FAQ & Clinical Guidance
What is the diagnostic accuracy of the SETD5 gene NGS test?
Quick Answer: The test achieves over 99.9% analytical sensitivity and specificity for detecting single nucleotide variants and small insertions/deletions in the SETD5 gene. This means that if a pathogenic variant is present, the will identify it with near certainty. Clinical interpretation by a certified molecular geneticist ensures reliable results.
يحقق الاختبار دقة تحليلية تتجاوز 99.9% في اكتشاف الطفرات في جين SETD5، مما يجعله أداة تشخيصية موثوقة.
How is the home blood collection service performed and is it safe?
Quick Answer: A DHA-licensed phlebotomist visits your home using a hospital-grade, cold-chain kit to collect 3 mL of venous blood, ensuring sample integrity from vein to lab. The procedure is painless and follows strict infection control protocols in compliance with UAE Federal Decree-Law No. 41 of 2024. No fasting is required.
يقوم فني مختص بسحب عينة دم وريدي في منزلك باستخدام مجموعة تبريد طبية معقمة، مع الالتزام بأعلى معايير السلامة.
Will my genetic data be protected under UAE privacy laws?
Quick Answer: Yes, all genetic data is fully protected under the UAE Personal Data Protection Law (PDPL) and stored in encrypted, ISO-certified servers. Your results are only shared with your ordering physician and are never disclosed to employers or insurers without explicit consent. We adhere to Federal Decree-Law No. 41 of 2024 Article 87 regarding laboratory confidentiality.
نعم، البيانات الجينية محمية بموجب قانون حماية البيانات الشخصية لدولة الإمارات، وتخزَّن في خوادم مشفرة معتمدة.
Regulatory & Quality Compliance
This service is provided by a DHA-licensed facility (License: 9834453) and adheres to:
- ISO 9001:2015 Quality Management (Cert: INT/EGQ/2509DA/3139)
- UAE Federal Decree-Law No. 41 of 2024 on Medical Laboratories – Article 87
- UAE CDS Law 2026 for Minors (informed consent from legal guardian)
- UAE Personal Data Protection Law (PDPL)
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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