Test Price
2,800 AED✅ Home Collection Available
SETD5 Gene Genetic Test for Autosomal Dominant Intellectual Disability Type 23 (MRD23) in UAE | AED 2800 | DHA Licensed
Executive Summary & Core Metrics
Key Trust Signals:
- Diagnostic Sensitivity: 99.9% via ISO 9001:2015 Certified NGS (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Post-Test Guidance: Telephonic clinical interpretation by a DHA-licensed physician.
- Insurance Support: Direct billing verification via WhatsApp at +971 54 548 8731.
Clinical Utility: Single-gene NGS analysis for definitive diagnosis of autosomal dominant intellectual disability type 23. Results delivered within 3–4 weeks with expert genetic counseling.
Test Overview & Methodology
The SETD5 gene sequencing test uses Next-Generation Sequencing (NGS) to detect pathogenic variants in the SETD5 gene, which cause autosomal dominant intellectual disability type 23 (MRD23). A pre-test genetic counselling session is required to draw a pedigree chart of affected family members.
| Feature | Our SETD5 NGS Test | Closest Alternative (Exome Sequencing) |
|---|---|---|
| Precision | Single-gene full coding region + flanking introns; >99.9% analytical sensitivity | Whole-exome coverage may miss deep intronic variants |
| Methodology | NGS with Sanger confirmation of pathogenic variants | Exome capture + NGS, often without reflex confirmation |
| Turnaround Time | 3–4 weeks | 8–12 weeks |
Physician Insight & Safety Protocols
A Note from Lina Osama Zaki Quteineh – Consultant Medical Genetics (DHA ID: 9294403)
"The SETD5 variant is a rare cause of intellectual disability, and its identification through targeted NGS offers families a precise diagnosis. I always emphasize that results must be interpreted alongside a thorough clinical and developmental assessment. I am available for telephonic post-test counseling to help patients and families understand the implications and next steps."
Advisory & Pre-Test Requirements
Important Pre-Test Notes
Genetic counseling is mandatory before testing. A detailed family history and informed consent must be obtained. Minors require parental or guardian consent in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability. Do not discontinue any prescribed medications without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients with acute illness or those unable to provide informed consent. Minors require guardian consent as per UAE law.
- Red Flags: If the individual experiences new-onset seizures, severe behavioral regression, or loss of previously acquired skills, seek immediate emergency medical attention at a DHA-licensed facility.
- Sample rejection: Hemolyzed or clotted blood; insufficient DNA quantity.
Patient FAQ & Clinical Guidance
1. What is the diagnostic accuracy of the SETD5 gene NGS test?
Quick Answer: The test achieves over 99.9% analytical sensitivity and specificity for detecting single nucleotide variants and small insertions/deletions in the SETD5 gene. This means that if a pathogenic variant is present, the test will identify it with near certainty. Clinical interpretation by a certified molecular geneticist ensures reliable results.
2. How is the home blood collection service performed and is it safe?
Quick Answer: A DHA-licensed phlebotomist visits your home using a hospital-grade, cold-chain kit to collect 3 mL of venous blood, ensuring sample integrity from vein to lab. The procedure is painless and follows strict infection control protocols in compliance with UAE Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. No fasting is required.
3. Will my genetic data be protected under UAE privacy laws?
Quick Answer: Yes, all genetic data is fully protected under the UAE Personal Data Protection Law (Federal Decree-Law No. 45 of 2021) and stored in encrypted, ISO-certified servers. Your results are only shared with your ordering physician and are never disclosed to employers or insurers without explicit consent. We adhere to Federal Law No. 2 of 2019 for health data security.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This service is provided by a DHA-licensed facility (License: 1143) and adheres to:
- ISO 9001:2015 Quality Management (Cert: INT/EGQ/2509DA/3139)
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL)
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields
- Federal Decree-Law No. 4 of 2016 on Medical Liability for patient safety and consent
Clinical & Logistical Metadata
| Test Name | SETD5 Gene Sequencing for Autosomal Dominant Intellectual Disability Type 23 (MRD23) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole Blood (3 mL) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | F79, Z14.8, Z13.79 |
| LOINC Code | 81247-9 |
| DHA Facility License & Laboratory Address | License: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians