Also known as: Antithrombin III Deficiency Genetic Test, SERPINC1 Gene Sequencing
Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3โ4 Weeks
SERPINC1 Gene Antithrombin III Deficiency Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all Emirates.
- Clinical Guidance: Complimentary Telephonic Post-Test Consultation for result interpretation by a DHA-licensed Consultant Medical Genetics.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test leverages Next Generation Sequencing to analyze the entire coding region of the SERPINC1 gene, detecting single nucleotide variants, small indels, and copy number variations linked to hereditary antithrombin III deficiencyโa major thrombophilia condition. The assay covers all exons ยฑ20 bp intronic boundaries with validated CNV detection, delivering diagnostic sensitivity exceeding 99.9% for point mutations and indels.
โณ Pre-test Requirement: A comprehensive genetic counseling session is mandatory prior to sample collection, where a certified genetic counselor will draw a detailed family pedigree and review your medical history to ensure accurate risk assessment and compliance with UAE healthcare regulations.
| Feature | Our Test (NGS & ISO Certified) | Closest Alternative (Standard Sanger Sequencing) |
|---|---|---|
| Method | NGS with 100% coverage of SERPINC1 exons ยฑ20 bp intronic boundaries; CNV analysis included | Sanger sequencing of selected exons; limited CNV detection |
| Sensitivity & Specificity | >99.9% diagnostic sensitivity for point mutations and indels; validated by ISO 9001:2015 | ~95% for targeted regions; may miss deep intronic or large rearrangements |
| Turnaround Time | 3โ4 Weeks with comprehensive clinical report | 2โ3 Weeks (often with limited interpretive support) |
Physician Insight & Safety Protocols
โGenetic predisposition does not guarantee clinical disease, and a normal result does not exclude acquired deficiency. We strongly advise interpreting this test alongside a full thrombophilia workup and family history. Testing should never replace clinical vigilance.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Safety Advisory
โ ๏ธ Critical Advisory
Do not discontinue prescribed anticoagulant or any medication without consulting your treating physician. Abrupt cessation can trigger life-threatening thrombosis. Always consult your specialist before making any changes to your medication regimen.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Receipt of blood transfusion or bone marrow transplant within the last 3 months may compromise DNA analysis.
- Minors: Testing for individuals under 18 years requires mandatory genetic counseling and legal guardian consent in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- ER Red Flags: Seek emergency care immediately if you experience sudden severe leg swelling or pain, chest pain, difficulty breathing, or signs of stroke (facial droop, arm weakness) โ these may indicate acute thrombosis.
Patient FAQ & Clinical Guidance
1. What does the SERPINC1 gene test detect and why is it important?
This test identifies inherited mutations in the SERPINC1 gene that cause antithrombin deficiency, a condition increasing lifelong risk of deep vein thrombosis, pulmonary embolism, and recurrent miscarriage if unrecognized. Early detection enables targeted prophylaxis and informed family planning.
2. How is the sample collected and is home service available in the UAE?
Our ISO-certified mobile phlebotomy team provides a peripheral blood draw at your home, office, or hotel across all Emirates using temperature-controlled cold-chain logistics, available daily from 8:00 AM to 11:00 PM.
3. When can I expect my results and what support is provided afterward?
Your comprehensive genetic report is delivered within 3 to 4 weeks, accompanied by a complimentary post-test teleconsultation with our clinical team to explain implications and guide next steps.
UAE Regulatory & Data Privacy Adherence
Your data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical testing, patient safety, and consent protocols comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE maintains strict confidentiality and secure handling of all genetic information.
Clinical & Logistical Metadata
| Test Name | SERPINC1 Gene Antithrombin III Deficiency Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) |
| Methodology Used | Next Generation Sequencing (NGS) โ Full gene coding regions ยฑ20 bp intronic boundaries, including CNV analysis |
| ICD-10-CM Code | D68.51 |
| LOINC Code | 90368-6 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
Preparation Required
["Genetic counseling session is mandatory prior to sample collection.", "No specific fasting or medication adjustments are required for the blood draw."]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians