Test Price
2,800 AEDโ Home Collection Available
SECISBP2 Gene Thyroid Hormone Metabolism Abnormalities Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Assurance: Diagnostic sensitivity exceeding 99.9% via ISO-accredited processing and rigorous bioinformatic validation.
- Logistics Excellence: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Medical Guidance: Post-test telephonic consultation with a Consultant Medical Genetics clinician to interpret results and outline management pathways.
- Insurance Facilitation: Direct verification and billing assistance available via WhatsApp at +971545488731.
Test Overview & Methodology
The SECISBP2 gene test employs Next Generation Sequencing (NGS) to detect pathogenic variants that disrupt thyroid hormone metabolism and selenoprotein synthesis. This targeted analysis links genetic etiology to multi-system disorders affecting hepatology, nephrology, and endocrinology, providing definitive molecular insight for precise clinical management and familial risk stratification.
| Feature | SECISBP2 NGS Gene Panel โ DNA Labs UAE | Standard Thyroid Function Tests |
|---|---|---|
| Precision | >99.9% analytical sensitivity and specificity for target gene mutations | Limited to hormone concentrations; no genetic insight |
| Methodology | NGS (Illumina NovaSeq) with advanced bioinformatics pipeline | Immunoassay (TSH, T3, T4) |
| Turnaround Time | 3โ4 Weeks | Same Day |
| Clinical Value | Definitive genetic diagnosis guiding targeted therapy and family cascade screening | Screening only; does not identify underlying genetic cause |
Physician Insight & Safety Protocols
โUncovering a genetic variant in the SECISBP2 pathway provides a powerful lens into thyroid hormone regulation, yet these findings must be correlated with a patient's full clinical presentation, biochemical profile, and family history. My commitment is to walk alongside you through every stage of interpretation, ensuring that the molecular data translates into meaningful, actionable care. Always remember that a genetic finding is not a standalone diagnosis; it requires comprehensive evaluation by a specialist team.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Critical Safety Advisory
Do not alter or discontinue any prescribed thyroid medication without direct consultation with your treating endocrinologist. Genetic testing results are intended to guide long-term management strategies and should never be used to make acute treatment decisions.
Exclusion Criteria & Emergency Red Flags
- Patients under 18 years require legal guardian consent in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- This test is not intended for acute medical emergencies or critical care settings.
- Seek immediate emergency care if you experience sudden severe thyroid storm symptoms (high fever, rapid heart rate, agitation, confusion) or signs of myxedema coma (extreme fatigue, hypothermia, loss of consciousness). Do not delay emergency treatment while awaiting genetic results.
Patient FAQ & Clinical Guidance
1. What does the SECISBP2 genetic test detect?
A: This test identifies pathogenic variants in the SECISBP2 gene that disrupt thyroid hormone metabolism and selenoprotein synthesis, enabling precise diagnosis of a rare genetic disorder affecting multiple organ systems.
2. Is genetic counseling required before testing?
A: Yes, a pre-test genetic counseling session is mandatory to construct a three-generation family pedigree, discuss implications of possible results, and obtain informed consent in compliance with UAE regulatory standards.
3. How long does it take to receive results?
A: Due to the rigorous sequencing and clinical interpretation process, the standard turnaround time is three to four weeks from sample receipt at the laboratory.
4. Can this test be performed on an archival tissue sample?
A: No, this test requires a fresh whole blood specimen for DNA extraction. Archival tissue blocks or slides are not suitable for this NGS-based analysis. Secure Medical Courier Solid Tissue Specimen Retrieval is not applicable for this test.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This genetic testing service fully complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is handled under strict confidentiality protocols with encrypted storage and access controls. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | SECISBP2 Gene Thyroid Hormone Metabolism Abnormalities Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) |
| Methodology Used | Next Generation Sequencing (NGS) โ Illumina NovaSeq |
| ICD-10-CM Code | E07.89 |
| LOINC Code | 21636-6 |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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