Test Price
2,800 AED✅ Home Collection Available
SDHA Gene Leigh Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل SDHA Gene Leigh Syndrome بالفحص الجيني الجزيئي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Clinical Excellence Guarantee
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited NGS platform (Cert: INT/EGQ/2509DA/3139).
- VIP Home Collection: ISO-certified cold-chain mobile phlebotomy by DHA-licensed nurses, 8 AM – 11 PM.
- Post-Test Clinical Guidance: Telephonic result interpretation by Dr. PRABHAKAR REDDY (DHA-61713011).
- Insurance Integration: Direct billing verification via WhatsApp at +971 54 548 8731.
يضمن هذا الفحص أعلى دقة تشخيصية وفق معايير الآيزو العالمية وهيئة الصحة بدبي، مع استشارة وراثية كاملة قبل وبعد الفحص.
Test Overview
The SDHA Gene Leigh Syndrome NGS test is a comprehensive next-generation sequencing assay that analyzes the entire coding region and splice junctions of the SDHA gene, detecting single nucleotide variants, insertions/deletions, and copy number variations (CNVs) with deep coverage. يكتشف الطفرات الجينية المسببة لمتلازمة لي المرتبطة بجين SDHA باستخدام أحدث تقنيات التسلسل الجيني. This test is essential for confirming a clinical suspicion of Leigh syndrome, guiding targeted therapy, and enabling accurate family risk assessment.
| Feature | Our Test (NGS Full Gene + CNV) | Closest Alternative (Targeted Panel) |
|---|---|---|
| Methodology | Illumina NovaSeq + ACMG 2025 variant interpretation | Sanger sequencing of selected exons |
| Sensitivity | >99.9% for all variant types | ~85% (misses large deletions/CNVs) |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Sample Requirement | Blood, Extracted DNA, or Dried Blood Spot (FTA Card) | Blood only |
Physician Insight & Safety Protocol
“As a DHA-licensed Consultant Clinical Geneticist (License: 61713011), I emphasize that this NGS test provides high-resolution genotyping of the SDHA gene. However, a pathogenic variant report must always be correlated with the patient’s clinical phenotype, brain MRI findings, and biochemical markers (e.g., elevated lactate/pyruvate ratio). A negative result does not rule out other mitochondrial disorders or complex II deficiency due to alternative genes. Please use this information in conjunction with your neurologist or metabolic specialist’s evaluation.”
— Dr. PRABHAKAR REDDY, DHA: 61713011
Do not discontinue prescribed medication without consulting your doctor.
Patient Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Acute metabolic decompensation or critical illness requiring immediate medical stabilization. Test should be postponed until the patient is clinically stable.
- Exclusion: Inability to provide informed consent (mandatory genetic counseling).
- ER Red Flag: Sudden onset of seizures, loss of consciousness, or stroke-like episodes—seek emergency care immediately; do not delay for this outpatient genetic test.
- ER Red Flag: Rapid neurological deterioration in a child suspecting Leigh syndrome—this test is not intended for acute diagnosis; urgent metabolic workup is required first.
Patient FAQ & Clinical Guidance
1. What exactly does the SDHA Gene Leigh Syndrome NGS test detect?
This sequences the entire SDHA gene using next-generation sequencing to identify pathogenic mutations that cause Leigh syndrome, a severe mitochondrial disorder.
يحدد هذا التحليل الطفرات المرضية في جين SDHA المسببة لمتلازمة لي عبر التسلسل الجيني الكامل للجين، مما يساعد في التشخيص الدقيق.
2. How is the sample collected and is a hospital visit required?
A DHA-licensed phlebotomist visits your home or office (8 AM – 11 PM) to collect a simple blood sample or a finger-prick dried blood spot on an FTA card.
يقوم فني سحب دم مرخص من هيئة الصحة بدبي بزيارة منزلية لجمع عينة دم بسيطة أو بقعة دم جافة على بطاقة FTA، دون الحاجة لزيارة المستشفى.
3. How long will it take to receive my results and what do they include?
Your comprehensive report, including variant classification according to ACMG 2025 standards, clinical interpretation, and genetic counseling recommendations, is delivered within 3–4 weeks.
تستلم تقريرك الشامل خلال 3-4 أسابيع، ويشمل تفسير المتغيرات الوراثية وفق معايير ACMG، وتوصيات الاستشارة الوراثية، وخطة المتابعة الطبية.
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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