Test Price
2,800 AED✅ Home Collection Available
ROBO3 Gene Horizontal Gaze Palsy with Progressive Scoliosis (HGPPS) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
The ROBO3 Gene NGS Test detects pathogenic variants in the ROBO3 gene, confirming a diagnosis of Horizontal Gaze Palsy with Progressive Scoliosis (HGPPS), a rare congenital disorder characterized by absent horizontal eye movements and early-onset scoliosis. This test employs Next-Generation Sequencing (NGS) for comprehensive coverage of all coding regions and splice sites.
| Feature | Our Test (NGS Panel) | Conventional Sanger Sequencing |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) | Targeted Single Exon Sequencing |
| Diagnostic Yield | >99.9% coverage of all ROBO3 coding regions | Limited to known mutations; may miss novel variants |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA ID: 9294403): A positive genetic result for a ROBO3 mutation confirms the diagnosis but must be correlated with clinical findings and imaging studies. This genetic insight empowers families to plan early interventions for scoliosis and seek multidisciplinary care. Always interpret results within the complete clinical context, not as a standalone verdict.
Medication Safety Advisory
Do not discontinue any prescribed medication without consulting your physician.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Individuals lacking clinical features suggestive of HGPPS or who have not undergone mandatory genetic counselling as per UAE Federal Law No. 2 of 2019. Genetic testing on minors requires explicit legal guardian consent under the same law.
- Emergency Red Flags: Sudden onset of breathing difficulty, rapid worsening of spinal curvature with severe pain, new visual loss, or unexplained neurological decline. Seek urgent medical attention immediately.
Patient FAQ & Clinical Guidance
1. What is the ROBO3 gene test used for?
This NGS test detects ROBO3 gene mutations causing Horizontal Gaze Palsy with Progressive Scoliosis (HGPPS) for diagnostic confirmation. Results guide neurological and orthopedic management.
2. Why is genetic counselling mandatory before the test?
Genetic counselling is legally required under UAE Federal Law No. 2 of 2019 to ensure patients and families understand the implications of results, including recurrence risks and family planning options.
3. How long does it take to receive results?
Results are typically available within 3 to 4 weeks from sample receipt at our ISO-certified laboratory. Urgent cases can be prioritized upon physician request via WhatsApp.
UAE Regulatory & Data Privacy Adherence
All genetic data and personal health information are processed in strict accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Our laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139). Genetic counselling is mandatory prior to testing, and all clinical procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | ROBO3 Gene Horizontal Gaze Palsy with Progressive Scoliosis (HGPPS) Genetic Test |
| Price (AED) | 2800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (3–5 mL in EDTA tube) |
| Methodology Used | Next-Generation Sequencing (NGS) – Whole Gene Sequencing |
| ICD-10-CM Code | H51.8 |
| LOINC Code | 96993-9 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians