Test Price
2,800 AEDโ Home Collection Available
RIPK4 Gene (Popliteal Pterygium Syndrome, Lethal Type) Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
Core Metrics
This advanced genetic test utilizes Next-Generation Sequencing (NGS) for the RIPK4 gene, essential for diagnosing lethal popliteal pterygium syndrome. With 99.9% diagnostic sensitivity via ISO accredited processing (Cert: INT/EGQ/2509DA/3139), the test includes VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM. Post-test telephonic clinical guidance is provided with a DHA-certified genetic consultant. Direct billing verification is available via WhatsApp.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance with a DHA-certified genetic consultant.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The RIPK4 gene test is a definitive NGS assay for diagnosing lethal popliteal pterygium syndrome, a rare autosomal recessive disorder characterized by webbing of skin, cleft palate, and severe craniofacial anomalies. Our UAE-based test provides unmatched precision, detecting single nucleotide variants, indels, and copy number variations across all coding exons with a turnaround time of 3โ4 weeks.
| Feature | Our RIPK4 NGS Test | Traditional Sanger Sequencing |
|---|---|---|
| Methodology | NGS (Massively Parallel) | Single-capillary sequencing |
| Coverage | 100% coding exons + splice sites | Selected exons only |
| Variants Detected | SNVs, Indels, CNVs | SNVs, small indels |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks |
| Price | 2,800 AED | Often comparable |
| UAE DHA Compliance | Full & Certified | Varies by lab |
Physician Insight & Safety Protocols
โAs a consultant medical geneticist with years of experience in prenatal and pediatric dysmorphology, I emphasize that this test is a powerful tool when paired with careful clinical correlation and family history. A negative result does not rule out all genetic causes, and a positive result must be interpreted in the context of the patientโs phenotype. Never discontinue any prescribed medication or pregnancy management without direct consultation with your specialist.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA: 9294403
Safety Advisory & Sample Integrity
Strict cold-chain adherence per ISO 9001:2015; any deviation during home collection must be reported to +971 54 548 8731. All samples are handled under DHA-approved protocols.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Recent allogeneic blood transfusion (<2 weeks) or severely lipemic/hemolyzed samples may be rejected; extracted DNA from buccal swab bypasses these restrictions.
- Red Flags: If the patient (especially a neonate) develops respiratory distress, severe feeding difficulties, or signs of infection at the collection site, seek immediate emergency care. This test is not a substitute for urgent clinical evaluation.
- Sample Integrity: Strict cold-chain adherence per ISO 9001:2015; any deviation during home collection must be reported to +971 54 548 8731.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of RIPK4 gene testing?
The test confirms definitive diagnosis, guides surgical planning, and enables accurate recurrence risk counseling for families. It differentiates lethal popliteal pterygium syndrome from non-lethal forms, informs neonatal intensive care strategies, and supports early decision-making in affected pregnancies.
2. How is the sample collected and what sample types are accepted?
VIP Mobile Phlebotomy provides home collection of whole blood (EDTA tubes, 2-3 mL) or sterile FTA cards requiring only a few drops. Pre-extracted DNA from a buccal swab is also accepted. All samples are transported via temperature-controlled cold chain.
3. What is the turnaround time and what actions follow a positive result?
Results are available within 3โ4 weeks. Upon detection of a pathogenic variant, our team contacts you to schedule a telephonic session with a clinical geneticist and coordinates with a pediatric dysmorphology center in UAE for further management.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Privacy
This service operates under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic information is processed in an encrypted, Dubai-based infrastructure and is never shared without explicit consent. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DHA Facility License: 1143.
Clinical & Logistical Metadata
| Test Name | RIPK4 Gene (Popliteal Pterygium Syndrome, Lethal Type) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), FTA Card, or Buccal Swab (Extracted DNA accepted) |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full Coding Exons & Splice Sites |
| ICD-10-CM Code | Q87.0 (Congenital malformation syndromes predominantly affecting facial appearance) โ Popliteal pterygium syndrome |
| LOINC Code | 48767-8 (Gene mutation analysis) |
| DHA Facility License & Laboratory Address | License: 1143 Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab: DNA Labs UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians