Test Price
2,800 AED✅ Home Collection Available
RAG1 Gene (Severe Combined Immunodeficiency, B‑cell Negative) Genetic Test in UAE 2800 AED | 2026 DHA Guidelines – ISO 9001 Certified
تحليل جين RAG1 لنقص المناعة المشترك الشديد (سلبي الخلايا البائية) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: يضمن اختبار تسلسل الجين RAG1 الكامل بتقنية NGS تشخيصاً دقيقاً لنقص المناعة المشترك الشديد (SCID) بحساسية تصل إلى 99.9%، وفقاً لأحدث إرشادات هيئة الصحة بدبي لعام 2026 وتحت اعتماد ISO 9001:2015. يشمل الخدمة جمع عينة منزلية آمنة عبر سلسلة تبريد معتمدة وجلسة تفسير سريري هاتفية بعد النتيجة.
Test Overview
The RAG1 gene NGS test detects pathogenic variants causing severe combined immunodeficiency (SCID) with absent B cells, a life‑threatening disorder where affected children lack functional lymphocytes. اختبار جيني شامل يكشف طفرات الجين RAG1 المسبِّب لنقص المناعة المشترك الشديد لدى الأطفال. Early molecular diagnosis is critical for lifesaving interventions like haematopoietic stem cell transplantation.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision / Coverage | Full RAG1 gene NGS + CNV analysis, 100% coding exons, Sanger confirmation | Targeted mutation panel (limited set of known variants) |
| Methodology | Next‑Generation Sequencing (NGS) – 2026 standard | Sanger sequencing or array‑based screening |
| Turnaround Time | 3‑4 weeks (comprehensive analysis) | 4‑6 weeks (often without CNV detection) |
Physician Insight & Safety Protocol
Dr. Prabhakar Reddy (DHA License 61713011): “No parent should face a SCID diagnosis alone — this test gives families the clarity to pursue early curative therapies. We combine genetic precision with a compassionate approach to interpret your child’s result, always correlating with clinical findings.”
Critical Safety Notice
⚠️ Do not discontinue any prescribed medication, especially immunoglobulin replacement or prophylactic antibiotics, without explicit instruction from your treating physician.
- Exclusion Criteria: Asymptomatic individuals with no family history or clinical suspicion; test not for general newborn screening.
- Paediatric Consent: Mandatory signed parental/guardian consent per UAE CDS Law 2026 (minors).
- ER Red Flags: Fever ≥38.5 °C, new rash with respiratory distress, or lethargy in a child suspected of SCID — seek emergency care immediately.
- Interpretation Requirement: Results must be reviewed by a clinical geneticist or immunologist; variants of uncertain significance require family segregation studies.
This test is regulated under UAE Federal Decree‑Law No. 41 of 2024 (Article 87) and the UAE Personal Data Protection Law. All genetic data is processed in an ISO 9001:2015 certified facility (Cert: INT/EGQ/2509DA/3139).
Patient FAQ & Clinical Guidance
1. What exactly does the RAG1 gene test look for?
This test screens the entire RAG1 gene for DNA sequence variants and deletions that abolish the protein’s ability to rearrange immune receptor genes, causing SCID. It detects single nucleotide changes, small insertions/deletions, and copy number imbalances, all of which can lead to B‑cell‑negative severe combined immunodeficiency, a condition presenting in infancy with recurrent infections and failure to thrive.
يبحث هذا الاختبار في كامل جين RAG1 عن طفرات تسلسلية أو حذف يمنع تكوين المستقبلات المناعية، مما يؤدي إلى نقص المناعة المشترك الشديد.
2. Why does the result take 3 to 4 weeks?
Turnaround time of 3‑4 weeks reflects the meticulous steps of DNA extraction, NGS library preparation, sequencing, bioinformatic analysis, and confirmatory Sanger validation. Every variant is cross‑referenced against the latest 2026 ClinVar and gnomAD databases, and each report is manually reviewed by a PhD molecular geneticist to ensure the highest diagnostic accuracy before release to your referring physician.
تستغرق النتيجة من 3 إلى 4 أسابيع بسبب خطوات استخلاص الحمض النووي وتحضير المكتبة والتسلسل وتحليل المعلوماتية الحيوية مع التحقق التأكيدي، لضمان الدقة القصوى.
3. Can I book a home visit for my baby?
Yes, our paediatric‑trained phlebotomists perform hospital‑grade home collection for babies and children, using a small‑volume EDTA tube or a painless FTA card spot. The sample is immediately placed in a validated cold‑chain transport and sent to our ISO‑certified genomics lab; you can schedule via WhatsApp (+971 54 548 8731) from 8 AM to 11 PM daily, and we coordinate with your health insurance directly.
نعم، نوفر خدمة سحب منزلية للأطفال والرضّع بواسطة فنيين مختصين، مع نقل العينة بسلسلة تبريد معتمدة. احجز عبر واتساب خلال ساعات العمل.
Pre‑test Information & Genetic Counselling
- A detailed clinical history questionnaire must be completed, including any known affected family members and consanguinity status.
- Mandatory pre‑test genetic counselling session to draw a pedigree chart of family members affected by SCID or RAG1‑related disorders; this ensures accurate risk assessment and interpretation.
- Sample collection options (choose one): Whole Blood (EDTA tube, 2‑3 mL) OR Extracted DNA (≥2 µg) OR One drop of blood on FTA card – all shipped in temperature‑controlled kit provided during home collection.
- Do NOT stop any current medications, including immunoglobulin infusions or prophylactic antibiotics, without physician advice.
- For minor patients, a signed consent form from both parents/legal guardians is required under UAE CDS Law 2026; a copy of the child’s Emirates ID must be provided.
- Insurance pre‑authorisation: WhatsApp a copy of your insurance card to +971 54 548 8731; we verify coverage and handle direct billing where approved.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians