Test Price
2,800 AED✅ Home Collection Available
PSEN1 Gene Acne Inversa (Familial Type 3) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين PSEN1 لحب الشباب العكسي العائلي من النوع الثالث في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Next-Generation Sequencing (NGS) with clinical-grade variant interpretation.
Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Phlebotomy & VIP Mobile Phlebotomy.
Clinical Guidance: Telephonic Post-Test Clinical Guidance with Dr. Prabhakar Reddy (DHA: 61713011) for result interpretation.
Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
الفحص الجيني المتطور PSEN1 بتقنية التسلسل الجيني فائق الدقة (NGS) لكشف الطفرات المسببة لحب الشباب العكسي العائلي، معتمدة من الهيئات الصحية بدولة الإمارات.
Overview
This test uses Next-Generation Sequencing (NGS) to analyse the entire coding region of the PSEN1 gene for pathogenic variants linked to familial acne inversa (hidradenitis suppurativa) type 3. The analysis provides a definitive molecular diagnosis, informs personalised treatment strategies, and identifies at-risk family members.
تحليل جين PSEN1 بتقنية التسلسل الجيني المتقدم يوفر تشخيصًا دقيقًا لحب الشباب العكسي العائلي من النوع الثالث، مما يمكّن من العلاج الموجه والاستشارة الوراثية.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | Targeted full-gene NGS with >99.9% analytical sensitivity | Single-exon Sanger; may miss deep intronic or promoter variants |
| Methodology | Illumina NovaSeq X Plus / HiSeq NGS with advanced bioinformatics | Capillary electrophoresis; manual interpretation |
| Turnaround Time | 3–4 Weeks (comprehensive report) | 5–6 Weeks |
Physician Insight & Safety Protocol
“As a clinician committed to patient-centred genomic medicine, I advise that this PSEN1 analysis be interpreted in the context of full clinical presentation and family history. A positive result can empower early intervention and familial risk reduction, while a negative result may not exclude other genetic or environmental triggers. Your dermatologist remains the cornerstone of your care plan.”
— Dr. Prabhakar Reddy, DHA License 61713011.
⚠️ Medication Warning
Do not discontinue or modify any prescribed medication (e.g., biologics, antibiotics, retinoids) without consulting your treating physician. Genetic test results are not a substitute for ongoing clinical management.
🚑 Exclusion Criteria & Emergency Red Flags
- Patients under 18 years: genetic testing requires legally authorised guardian consent as per UAE CDS Law 2026.
- Active systemic infection, sepsis, or acute exacerbation of hidradenitis suppurativa with fever – seek immediate medical care; genetic testing is not an emergency diagnostic tool.
- Severe anaemia or coagulopathy that contraindicates venipuncture; an FTA card finger-prick sample is the safe alternative.
- If you experience sudden severe pain, spreading redness, or pus collection, proceed to the nearest emergency department regardless of pending test results.
Patient FAQ & Clinical Guidance
Q: What is the PSEN1 gene test for familial acne inversa (hidradenitis suppurativa)?
Snippet: NGS-based PSEN1 analysis confirms familial hidradenitis suppurativa type 3, guiding targeted therapy and family counselling.
الملخص: يؤكد تحليل جين PSEN1 بتقنية NGS تشخيص حب الشباب العكسي العائلي من النوع الثالث، مما يوجه العلاج والاستشارة العائلية.
Clinically, this test detects disease-causing mutations in the PSEN1 gene, which encodes a component of the γ-secretase complex critical for Notch signalling. Pathogenic variants disrupt keratinocyte differentiation and immune function, leading to chronic follicular occlusion. Results assist dermatologists in confirming diagnosis, predicting severity, and advising blood relatives about their risk.
Q: How is the sample collected and what is the process?
Snippet: Home phlebotomy service collects blood; PSEN1 NGS test detects acne inversa mutations in 3–4 weeks.
الملخص: خدمة سحب الدم المنزلي تجمع العينة؛ ويكشف فحص NGS طفرات جين PSEN1 خلال 3–4 أسابيع.
A trained phlebotomist visits your home, draws a small venous blood sample, and immediately transfers it into a DNA-stabilising tube under cold-chain conditions. Alternatively, a single drop of blood on an FTA card is accepted. DNA is extracted in our ISO-certified laboratory, enriched for the PSEN1 locus, and sequenced on high-throughput NGS platforms. Bioinformatics pipelines align reads, call variants, and annotate pathogenicity following ACMG/AMP guidelines.
Q: Is this genetic covered by health insurance in the UAE?
Snippet: WhatsApp verification confirms insurance coverage; UAE plans often reimburse PSEN1 testing for familial hidradenitis suppurativa.
الملخص: يؤكد التحقق عبر الواتساب تغطية التأمين؛ وغالباً ما تعوض خطط التأمين في الإمارات فحص PSEN1 للحب الشبابي العكسي العائلي.
We offer a direct billing verification service via WhatsApp (+971 54 548 8731). Simply send your insurance card, and our team will confirm coverage within minutes. Many UAE insurers consider PSEN1 testing medically necessary when there is a strong family history of hidradenitis suppurativa or clinical suspicion, making reimbursement straightforward under dermatology or genetic counselling benefits.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians