Test Price
2,800 AED✅ Home Collection Available
PRNP Gene Fatal Familial Insomnia Genetic Test in Dubai, UAE – NGS Sequencing at DNA Labs UAE
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Sequencing
Premium Hospital-Grade Home Collection (8 AM–11 PM) with ISO-Certified Cold-Chain Logistics. Includes Telephonic Post-Test Clinical Guidance by a DHA-Licensed Consultant Medical Genetics. Direct Insurance Billing Verification via WhatsApp at +971 54 548 8731.
In compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
Test Overview & Methodology
This Next-Generation Sequencing (NGS) test analyzes the entire coding region of the PRNP gene for pathogenic variants causing Fatal Familial Insomnia (FFI), a dominantly inherited prion disease. It offers complete mutation coverage with highest diagnostic confidence.
A pre-test genetic counselling session and a detailed pedigree chart are strongly recommended before sample collection. Acceptable specimens: Whole Blood, Extracted DNA, or Dried Blood Spot on FTA Card. Turnaround Time: 3–4 Weeks.
| Feature | Our Test (PRNP NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | Whole-gene coverage; detects all SNVs, indels, and copy number changes | Limited to known hotspots; may miss rare variants |
| Methodology | NGS (Next‑Generation Sequencing) on Illumina platform | Sanger sequencing |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks |
| Diagnostic Yield | >99% for PRNP mutations | ~85% for targeted mutations |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics at DNA Labs UAE, I emphasize that genetic testing for FFI must be accompanied by thorough pre- and post-test genetic counselling. A positive result indicates high lifetime risk but does not confirm active disease; clinical correlation with sleep studies and neurologic examination is essential.” – Lina Osama Zaki Quteineh (DHA License: 9294403)
Advisory – Medication Continuation
Do not discontinue any prescribed medications without prior consultation with your treating physician. Genetic test results do not replace ongoing clinical management.
Exclusion Criteria & Emergency Red Flags
- Minors under 18 years require explicit parental consent as per UAE legal guardianship rules.
- If you experience acute psychosis, sudden cognitive deterioration, or severe autonomic instability, seek immediate medical attention – this test is not a substitute for emergency care.
- Samples not transported in ISO‑compliant cold‑chain containers will be rejected.
Patient FAQ & Clinical Guidance
1. What exactly does this PRNP NGS test detect, and how accurate is it?
This sequences the entire coding region of the PRNP gene using NGS, delivering a 99.9% diagnostic sensitivity for all known Fatal Familial Insomnia‑causing mutations and associated prion disorders.
2. How is home sample collection handled, and is the transport safe?
Our DHA-certified phlebotomists collect whole blood or a dried blood spot on an FTA card at your home between 8 AM and 11 PM, immediately placing the sample in ISO-certified cold-chain carriers that maintain DNA stability throughout transit.
3. Will my genetic information remain confidential under UAE law?
All genetic data is protected under the UAE Personal Data Protection Law (PDPL) and handled exclusively within our ISO 9001:2015 certified laboratory; no third-party access is permitted without your express written consent.
UAE Regulatory & Data Privacy Adherence
This test is conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is ISO 9001:2015 certified and operates under DHA Facility License No. 1143.
Clinical & Logistical Metadata
| Test Name | PRNP Gene Fatal Familial Insomnia Genetic Test (NGS Sequencing) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Dried Blood Spot (FTA Card), or Extracted DNA |
| Methodology Used | Next‑Generation Sequencing (NGS) on Illumina Platform |
| ICD-10-CM Code | A81.83 |
| LOINC Code | 23504-4 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. Operated by DNA Labs UAE. |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians