Test Price
2,800 AED✅ Home Collection Available
PRNP Gene Fatal Familial Insomnia Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين PRNP للأرق العائلي المميت في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Sequencing
Premium Hospital-Grade Home Collection (8 AM–11 PM) with ISO-Certified Cold-Chain Logistics. Includes Telephonic Post-Test Clinical Guidance by a DHA-Licensed Neurologist. Direct Insurance Billing Verification via WhatsApp at +971 54 548 8731.
ملخص تنفيذي: يضمن هذا الاختبار الجيني باستخدام تسلسل الجيل التالي (NGS) حساسية تشخيصية بنسبة 99.9% للكشف عن طفرات جين PRNP المرتبطة بالأرق العائلي المميت. نجمع العينة منزلياً عبر فريق تمريض معتمد مع نقل مبرد وفق معايير ISO، ونقدم استشارة هاتفية بعد النتائج. التحقق من التغطية التأمينية عبر واتساب.
In compliance with Federal Decree-Law No. 41 of 2024 (Art. 87), UAE CDS Law 2026 (parental consent for minors), and UAE PDPL. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
Test Overview
This Next-Generation Sequencing (NGS) test analyzes the entire coding region of the PRNP gene for pathogenic variants causing Fatal Familial Insomnia (FFI), a dominantly inherited prion disease. It offers complete mutation coverage with highest diagnostic confidence. يكشف التحليل الكامل لجين PRNP عن الطفرات الوراثية المسببة للأرق العائلي المميت بأعلى دقة تشخيصية.
A pre-test genetic counselling session and a detailed pedigree chart are strongly recommended before sample collection. Acceptable specimens: Whole Blood, Extracted DNA, or Dried Blood Spot on FTA Card. Turnaround Time: 3–4 Weeks.
| Feature | Our Test (PRNP NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | Whole-gene coverage; detects all SNVs, indels, and copy number changes | Limited to known hotspots; may miss rare variants |
| Methodology | NGS (Next‑Generation Sequencing) on Illumina platform | Sanger sequencing |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks |
| Diagnostic Yield | >99% for PRNP mutations | ~85% for targeted mutations |
Physician Insight & Safety Protocol
“As a DHA-licensed Neurologist, I emphasize that genetic testing for FFI must be accompanied by thorough pre- and post-test genetic counselling. A positive result indicates high lifetime risk but does not confirm active disease; clinical correlation with sleep studies and neurologic examination is essential.” – Dr. PRABHAKAR REDDY (DHA License: 61713011)
⚠️ Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Minors under 18 years require explicit parental consent or a court order as per UAE CDS Law 2026.
- If you experience acute psychosis, sudden cognitive deterioration, or severe autonomic instability, seek immediate medical attention – this test is not a substitute for emergency care.
- Samples not transported in ISO‑compliant cold‑chain containers will be rejected.
Patient FAQ & Clinical Guidance
1. What exactly does this PRNP NGS test detect, and how accurate is it?
This sequences the entire coding region of the PRNP gene using NGS, delivering a 99.9% diagnostic sensitivity for all known Fatal Familial Insomnia‑causing mutations and associated prion disorders. يكشف تحليل تسلسل الحمض النووي الكامل لجين PRNP عن جميع الطفرات المسببة للأرق العائلي المميت بدقة تشخيصية تبلغ 99.9%.
2. How is home sample collection handled, and is the transport safe?
Our DHA-certified phlebotomists collect whole blood or a dried blood spot on an FTA card at your home between 8 AM and 11 PM, immediately placing the sample in ISO-certified cold-chain carriers that maintain DNA stability throughout transit. نجمع العينة منزلياً عبر فنيين معتمدين من هيئة الصحة بدبي، وننقلها في حاويات مبردة مطابقة لمعايير ISO لضمان استقرار الحمض النووي.
3. Will my genetic information remain confidential under UAE law?
All genetic data is protected under the UAE Personal Data Protection Law (PDPL) and handled exclusively within our ISO 9001:2015 certified laboratory; no third-party access is permitted without your express written consent. تحمي بياناتك الجينية بموجب قانون حماية البيانات الشخصية الإماراتي، وتُعالج حصرياً داخل مختبرنا الحاصل على شهادة ISO ولا تُشارك مع أي طرف خارجي دون موافقتك الصريحة.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians