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Test Price

2,800 AED

✅ Home Collection Available

POR Gene (Cytochrome P450 Oxidoreductase Deficiency) Adrenal Hyperplasia Genetic Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
  • Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (Available daily from 8 AM to 11 PM).
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by certified genetic counsellors.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This next-generation sequencing test analyses the entire coding region of the POR gene for pathogenic variants causing cytochrome P450 oxidoreductase deficiency – a rare form of congenital adrenal hyperplasia. It is a definitive molecular diagnosis tool for individuals with ambiguous genitalia, cortisol deficiency, or skeletal malformations.

Feature Our Test (NGS) Closest Alternative (Sanger)
Precision 99.9% analytical sensitivity for SNVs/indels ~95% sensitivity, limited to targeted regions
Methodology Next-Generation Sequencing (NGS) Sanger Sequencing (single amplicon)
Speed 3–4 Weeks (full gene) 4–6 Weeks (if ordered separately)

Physician Insight & Safety Protocols

“As your DHA-licensed Consultant Medical Genetics, I emphasize that a genetic finding is one piece of your health puzzle. Please do not interpret results in isolation; always correlate clinically with an endocrinologist. This test opens a door to precise management, not a final verdict.”

— Lina Osama Zaki Quteineh, DHA License No. 9294403

Medication Advisory

Do not discontinue prescribed medication (e.g., corticosteroids) without consulting your doctor. Abrupt withdrawal can trigger life-threatening adrenal crisis.

Exclusion Criteria & Emergency Red Flags

Do Not Proceed with Home Collection If:

  • You are currently pregnant or breastfeeding (unless clinically advised)
  • You received a blood transfusion within the last 4 weeks
  • Active severe infection or febrile illness (postpone until recovery)
  • Known history of anaphylaxis to phlebotomy materials

Seek Emergency Care Immediately If You Experience:

  • Signs of adrenal crisis: intractable vomiting, severe dehydration, hypotension, confusion
  • Unexplained rapid weight loss and marked hyperpigmentation
  • Electrolyte imbalance: severe hyponatremia or hyperkalemia
  • Acute abdominal pain with fever

Patient FAQ & Clinical Guidance

1. What does the POR gene NGS test detect?

This advanced DNA test identifies pathogenic variants in the POR gene causing cytochrome P450 oxidoreductase deficiency, a form of congenital adrenal hyperplasia.

2. How should I prepare for the test?

Preparation requires a prior genetic counselling session to document family history and a simple blood or DNA sample collection. Fasting is not required but it is recommended to have a light meal.

3. Is home collection available in the UAE?

Yes, we offer ISO-certified cold-chain home phlebotomy across all emirates from 8 AM to 11 PM daily. Our VIP mobile phlebotomy service ensures safe and temperature-controlled sample transport.

UAE Regulatory & Data Privacy Adherence

DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic data is encrypted, stored securely, and accessed only by authorized personnel for diagnostic purposes.

Clinical & Logistical Metadata

Test Name POR Gene (Cytochrome P450 Oxidoreductase Deficiency) NGS Test
Price (AED) 2,800 AED
Turnaround Time 3 to 4 Weeks
Sample Type / Matrix Whole Blood, Extracted DNA, or FTA Card
Methodology Used Next-Generation Sequencing (NGS)
ICD-10-CM Code E25.0, E25.8, Z13.228
LOINC Code 101404-8
DHA Facility License & Laboratory Address DHA License: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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