Test Price
2,800 AED✅ Home Collection Available
POLD1 Gene Mandibular Hypoplasia, Deafness, Progeroid Features, and Lipodystrophy (MDPL) Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل طفرة POLD1 لمتلازمة MDPL بالتسلسل الجيني المتقدم في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – Accurate, Compliant, and Patient‑Centric
Accuracy Guarantee: 99.9% Diagnostic Sensitivity confirmed by ISO 9001:2015 certified genetic laboratory (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Paid Hospital‑Grade Home Collection via ISO Certified Cold‑Chain Home Collection (Blood, DNA FTA Card) & VIP Mobile Phlebotomy – available daily 8 AM‑11 PM.
Clinical Guidance: Telephonic Post‑Test Clinical Guidance provided by Dr. Prabhakar Reddy (DHA License 61713011) to assist with result interpretation and clinical correlation.
Insurance: Direct Billing Verification & pre‑approval support via WhatsApp +971 54 548 8731.
استفد من خدمة السحب المنزلي المعتمد وتفسير النتائج عبر الهاتف من استشاري الوراثة الإكلينيكي (د. برابهاكار ريدي، ترخيص هيئة الصحة بدبي 61713011) مع دقة تشخيصية تصل إلى 99.9%.
Comprehensive POLD1 Gene MDPL Syndrome NGS Test Overview
The POLD1 gene NGS test definitively diagnoses MDPL syndrome – a rare autosomal dominant disorder characterised by mandibular hypoplasia, sensorineural deafness, progeroid features, and lipodystrophy. This test is ordered by Pediatricians, Anti‑Aging Specialists, and Medical & PhD Researchers to guide clinical management, family planning, and cutting‑edge research. Testing is performed on blood, extracted DNA, or a single drop of blood on an FTA card, with a turn‑around time of 3 to 4 weeks.
| Feature | Our Test (MDPL NGS) | Closest Alternative (Sanger / WES) |
|---|---|---|
| Precision | 99.9% Diagnostic Sensitivity – full gene coverage (coding & splice sites) | ~98% for targeted Sanger; WES may miss deep intronic variants |
| Methodology | Next‑Generation Sequencing (NGS) with bioinformatic variant classification per ACMG guidelines | Sanger sequencing (single gene) or whole exome (broader but lower depth) |
| Speed | 3–4 Weeks | 4–8 Weeks for WES; Sanger 2–3 Weeks |
Physician Insight & Safety Protocol
“As a physician, I understand the emotional weight of a possible genetic syndrome. This NGS test offers definitive molecular confirmation, but results must be correlated with a thorough clinical assessment and genetic counselling. Do not discontinue prescribed medication without consulting your doctor.” — Dr. Prabhakar Reddy (DHA License 61713011)
Medication Warning & Safety Exclusion
Do not discontinue any prescribed medication based solely on test results. Always consult your treating physician.
- Test not indicated for asymptomatic minors without formal genetic counselling and legal guardian’s informed consent (CDS Law 2026).
- Acute illness or metabolic crisis may temporarily postpone sample collection; consult our medical team.
- This is a clinical diagnostic test; for medico‑legal or forensic purposes, separate chain‑of‑custody arrangements are mandatory.
Emergency Red Flags: Seek immediate emergency care if the patient develops sudden severe hearing loss, respiratory distress, or signs of acute pancreatitis (severe abdominal pain, vomiting).
Patient FAQ & Clinical Guidance
1. What is the POLD1 Gene MDPL Syndrome NGS test and why is it used?
Snippet Answer: This NGS test analyzes the POLD1 gene to confirm diagnosis of mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome with 99.9% sensitivity. It enables precise clinical management, family risk assessment, and access to specialist care.
1. ما هو اختبار جين POLD1 لمتلازمة MDPL؟
يحلل اختبار تسلسل الجيل التالي جين POLD1 لتأكيد تشخيص متلازمة نقص تنسج الفك السفلي والصمم والسمات المرتبطة بالشيخوخة المبكرة والحثل الشحمي بدقة 99.9%.
2. Why is genetic counselling mandatory before this testing?
Snippet Answer: Genetic counselling ensures you understand the test’s implications, family impact, possible incidental findings, and guides informed consent. It is a DHA‑mandated prerequisite that protects your rights under UAE healthcare law.
2. لماذا يلزم الاستشارة الوراثية قبل الفحص؟
تضمن الاستشارة الوراثية فهمك الشامل لدلالات الاختبار وتأثيره على الأسرة والنتائج العرضية المحتملة قبل الموافقة المستنيرة.
3. How accurate is this test for MDPL syndrome, and what standards are followed?
Snippet Answer: With NGS technology and ISO 15189‑accredited lab, the achieves 99.9% diagnostic sensitivity for POLD1 mutations. All procedures comply with UAE Federal Decree‑Law No. 41 of 2024, CDS Law 2026, and PDPL data privacy regulations.
3. ما مدى دقة هذا الاختبار؟
باستخدام تقنية التسلسل الجيني المتقدم ومختبر معتمد ISO 15189، يحقق الاختبار حساسية تشخيصية 99.9% لطفرات POLD1.
Facility License: 9834453 | DHA Registered | Home Collection: 8 AM – 11 PM | WhatsApp +971 54 548 8731 | ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139)
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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