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Test Price

2,800 AED

✅ Home Collection Available

PIK3R5 Gene Ataxia‑Oculomotor Apraxia Type 3 Genetic Test in UAE | 2,800 AED | DHA Licensed Laboratory

Executive Summary & Core Metrics

  • Diagnostic Sensitivity: 99.9% via Next‑Generation Sequencing (NGS) – Full gene analysis under ISO 9001:2015 certification.
  • Home Collection: VIP Mobile Phlebotomy with temperature‑controlled cold‑chain logistics, available daily 8 AM – 11 PM.
  • Clinical Guidance: Post‑test teleconsultation with a Consultant Medical Genetics for result interpretation and family counselling.
  • Insurance Support: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

This advanced molecular genetic test detects pathogenic variants in the PIK3R5 gene associated with ataxia‑oculomotor apraxia type 3 (AOA3). Definitive diagnosis via NGS enables tailored neurology care, surveillance for associated complications, and multidisciplinary rehabilitation planning.

Feature DNA Labs UAE Test Closest Alternative
Precision 99.9% Diagnostic Sensitivity (NGS, full gene) ~95% (Sanger single‑exon screening)
Method Next‑Generation Sequencing (NGS) – ISO 9001:2015 Sanger Sequencing
Turnaround 3–4 Weeks (with genetic counselling support) 5–6 Weeks

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh – Consultant Medical Genetics (DHA Registration ID: 9294403)

“This molecular test provides definitive confirmation of ataxia‑oculomotor apraxia type 3, enabling precise genetic counselling and proactive management. Its full clinical value emerges when correlated with a complete neurological examination and family pedigree. I strongly recommend a pre‑test counselling session to ensure informed decision‑making.”

Genetic Counselling Advisory

A mandatory genetic counselling session and a three‑generation pedigree chart are required before sample collection. Our dedicated genetics team provides pre‑ and post‑test counselling support throughout the process.

Safety Exclusion Criteria & Clinical Red Flags

  • Incomplete clinical history or missing genetic counselling report.
  • Sample collected without verified guardian consent (mandatory for minors per Federal Decree‑Law No. 4 of 2016 on Medical Liability).
  • Acute neurological deterioration – seek emergency care immediately if severe ataxia, ophthalmoplegia, or respiratory distress occurs.

Patient FAQ & Clinical Guidance

1. What is the clinical significance of a positive PIK3R5 genetic test?

Answer: A positive result confirms the diagnosis of ataxia‑oculomotor apraxia type 3, enabling neurologists, clinical geneticists, and paediatric specialists to initiate surveillance for associated complications and plan multidisciplinary rehabilitation. Genetic counselling is recommended to discuss inheritance patterns and family planning options.

2. How should I prepare for sample collection?

Answer: A pre‑test genetic counselling session and a pedigree chart of affected family members are mandatory. Sample collection (peripheral blood in EDTA, extracted DNA, or a blood spot on an FTA card) is performed by our cold‑chain home phlebotomy team or at a designated clinic. Fasting is not required.

3. Is the test covered by UAE health insurance?

Answer: Most UAE health insurance policies cover medically indicated genetic testing when ordered by a neurologist or clinical geneticist. Direct billing verification is available via WhatsApp at +971 54 548 8731.

UAE Regulatory & Data Privacy Adherence

  • Federal Decree‑Law No. 45 of 2021 – Personal Data Protection Law (PDPL) – fully observed for all patient data.
  • Federal Law No. 2 of 2019 – Concerning the Use of Information and Communication Technology in Health Fields – governs secure health data handling.
  • Federal Decree‑Law No. 4 of 2016 – Medical Liability – ensures patient safety and informed consent compliance.
  • ISO 9001:2015 Certified – Cert: INT/EGQ/2509DA/3139.
  • DHA Facility License No: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE.

Clinical & Logistical Metadata

Test Name PIK3R5 Gene Ataxia‑Oculomotor Apraxia Type 3 Genetic Test
Price (AED) 2,800
Turnaround Time 3–4 Weeks (21–28 Business Days)
Sample Type / Matrix Peripheral Blood (EDTA), Extracted DNA, or FTA Card – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection Available
Methodology Used Next‑Generation Sequencing (NGS) – Full Gene Analysis, ISO 9001:2015 Certified
ICD-10-CM Code G11.1 (Early‑Onset Cerebellar Ataxia)
LOINC Code 81247-9 (PIK3R5 Gene Full Sequencing)
DHA Facility License & Laboratory Address License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE

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