Test Price
2,800 AED✅ Home Collection Available
PICALM Gene Genetic Test for Immunological & Dermatologic Disorders in UAE
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing. Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM. Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by our Consultant Medical Genetics. Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The PICALM Gene Genetic Test utilizes Next Generation Sequencing (NGS) to analyze the full coding region and splice sites of the PICALM gene. This advanced molecular analysis identifies pathogenic variants associated with immunological disorders, dermatologic conditions, and cancer predisposition. The test is performed on a peripheral whole blood sample and delivers comprehensive genetic insights within 3–4 weeks, enabling precise, personalized healthcare planning under specialist guidance.
| Feature | Our PICALM NGS Test | Standard Single-Gene Sanger Sequencing |
|---|---|---|
| Technology | Next Generation Sequencing (NGS) – full gene analysis | Sanger sequencing – targeted exon‑by‑exon (limited) |
| Coverage | All coding exons and splice sites of PICALM | Selected exons only; misses deep intronic variants |
| Diagnostic Sensitivity | 99.9% (ISO‑validated) | ~90–95% for the targeted region |
| Turnaround Time | 3–4 weeks from sample receipt | 4–6 weeks, often longer if reflex testing needed |
| Clinical Interpretation | Board‑certified geneticist report with management recommendations | Summary report, may require additional consultation |
Physician Insight & Safety Protocols
As a Consultant Medical Genetics, I emphasize that the PICALM NGS test is a powerful diagnostic tool, yet it must always be interpreted alongside a thorough clinical evaluation and three‑generation family pedigree. A negative result does not definitively exclude an immunological or dermatologic disorder, and any pathogenic finding should guide a personalized management plan under specialist supervision. Pre‑ and post‑test genetic counseling is integral to this process.
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Advisory
Please do not discontinue any prescribed medication without consulting your treating physician. Genetic test results are intended to inform clinical decision‑making and should not replace ongoing medical care.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Active severe systemic infection requiring immediate medical intervention; inability to provide informed consent (for minors, a legal guardian must consent).
- Emergency Red Flags: Seek immediate medical assistance if you experience loss of consciousness, uncontrolled bleeding at the venipuncture site, or signs of anaphylaxis (difficulty breathing, swelling of the face or lips) following sample collection.
This test is performed under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) and adheres to Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What does the PICALM gene test detect?
The PICALM NGS test identifies pathogenic variants associated with immunological, dermatologic, and certain oncological disorders with 99.9% diagnostic sensitivity. By analyzing the entire PICALM gene, the test reveals DNA changes that may elevate your risk for immune‑mediated diseases, skin conditions, or cancer, providing crucial data for early intervention and personalized care.
2. How should I prepare for the PICALM gene test?
No fasting is required. Please provide a three‑generation family pedigree and disclose all current medications during the mandatory genetic counseling session. A dedicated genetic counselor will review your medical and family history to ensure the test is appropriately interpreted and tailored to your clinical context.
3. What is the turnaround time for PICALM NGS results?
Results are available within 3 to 4 weeks following sample collection at our ISO‑certified laboratory in Dubai. This period allows for rigorous sequencing, comprehensive data analysis, and expert clinical interpretation, ensuring the highest accuracy. A detailed report is delivered securely to both you and your referring physician.
4. What sample type is required for this test?
A standard peripheral whole blood sample is required. Our VIP Mobile Phlebotomy service can collect the sample at your home between 8 AM and 11 PM daily, using temperature‑controlled cold‑chain logistics to maintain specimen integrity. Alternatively, you may visit our facility in Dubai Healthcare City.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Security: All genetic data is processed and stored in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic information is encrypted, access‑controlled, and never shared without your explicit consent. The laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and operates under the regulatory oversight of the Dubai Health Authority (DHA Facility License No. 1143).
Clinical & Logistical Metadata
| Test Name | PICALM Gene Genetic Test (Next Generation Sequencing) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks from sample receipt |
| Sample Type / Matrix | Peripheral whole blood |
| Methodology Used | Next Generation Sequencing (NGS) – full gene analysis |
| ICD-10-CM Code | Z13.89 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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