Test Price
2,800 AED✅ Home Collection Available
PDE8B Gene Striatal Degeneration Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139). Every variant confirmed by Sanger sequencing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic post-test clinical correlation session with a DHA-licensed medical geneticist to interpret results and plan next steps.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 (also phone).
Test Overview & Methodology
The PDE8B gene test screens for pathogenic variants causing autosomal recessive striatal degeneration, a progressive neurodegenerative disorder. Our high-depth NGS assay, combined with expert clinical interpretation, delivers actionable genetic insights within 3–4 weeks. The test covers full gene coding regions and flanking intronic sequences.
| Feature | Our PDE8B NGS Test | Closest Alternative (Single-gene Sanger) |
|---|---|---|
| Precision | >99.9% analytic sensitivity & specificity | ~98% (may miss copy-number variants) |
| Methodology | NGS (full gene coverage + flanking intronic regions) + Sanger confirmation | Sanger sequencing of coding exons only |
| Turnaround | 3–4 Weeks | 4–6 Weeks |
| ACMG Classification | Full 5-tier report with clinical correlation | Often binary positive/negative |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I understand the profound implications of genetic testing for neurodegenerative disorders. This test provides definitive molecular diagnosis for autosomal recessive striatal degeneration, but it must be interpreted within the context of complete clinical and family history. A positive result empowers proactive management and informed family planning.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Precautions
Important
Do not discontinue any prescribed medication (e.g., dopaminergic agents, antipsychotics, muscle relaxants) without consulting your treating physician. Abrupt withdrawal can precipitate severe neurological deterioration.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals under 18 without legal guardian consent (informed consent per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Exclusion: Active acute infection or blood transfusion within 2 weeks; non-fasting status is acceptable but must be disclosed.
- Emergency Red Flag: If you experience sudden rigidity, dystonic crisis, difficulty swallowing, or altered consciousness, proceed directly to the nearest Emergency Department—do not wait for genetic results.
Patient FAQ & Clinical Guidance
1. What does this PDE8B gene test detect, and why is it recommended?
It identifies pathogenic variants in the PDE8B gene that cause autosomal recessive striatal degeneration, helping to confirm diagnosis or inform family planning.
2. How should I prepare for the sample collection?
No fasting is required; a small blood sample, extracted DNA, or FTA card spot suffices—simply schedule home collection and maintain hydration.
3. How are results interpreted, and will I receive genetic counseling?
A board-certified molecular geneticist classifies variants using ACMG guidelines, and a DHA-licensed medical geneticist provides a telephonic consultation to explain clinical implications and follow-up steps.
UAE Regulatory & Data Privacy Adherence
Commitment to Compliance
All genetic testing is performed in strict adherence to UAE regulations: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) ensures genomic data is treated as sensitive personal information. Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields governs the secure handling of electronic health records. Informed consent is obtained per Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE (DHA License: 1143) operates from Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | PDE8B Gene Striatal Degeneration Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card spot |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | G23.8 (Other specified degenerative diseases of basal ganglia), G31.89 (Other specified degenerative diseases of nervous system) |
| LOINC Code | 58795-0 (PDE8B gene mutation analysis in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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