Test Price
2,800 AED✅ Home Collection Available
OCRL Gene Sequencing Test for Lowe Oculocerebrorenal Syndrome in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل جين OCRL لمتلازمة لوي (العينية الدماغية الكلوية) في الإمارات | 2800 درهم | إرشادات هيئة الصحة بدبي 2026
Executive Summary – Accurate, Compliant, and Patient‑Centric
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Hospital‑Grade Home Collection (8 AM – 11 PM) with ISO‑Certified Cold‑Chain Transport.
- Telephonic Post‑Test Clinical Guidance for result interpretation.
- Direct Insurance Billing Verification via WhatsApp: +971 54 548 8731.
الدقة التشخيصية 99.9% عبر معالجة معتمدة ISO. خدمة سحب الدم المنزلي المدفوعة مع نقل مبرد معتمد. استشارة إكلينيكية هاتفية بعد النتيجة. التأمين عبر واتساب.
Comprehensive Test Overview
This advanced Next‑Generation Sequencing (NGS) test analyses the entire OCRL gene for pathogenic variants causing Lowe oculocerebrorenal syndrome, a rare X‑linked disorder affecting the eyes, brain, and kidneys. يُستخدم هذا الفحص الجيني المتطور لتشخيص متلازمة لوي، وهو اضطراب نادر مرتبط بالكروموسوم X يؤثر على العين والدماغ والكلى.
| Parameter | Our Test (OCRL NGS) | Traditional Sanger Sequencing |
|---|---|---|
| Technology | Next‑Generation Sequencing | Sanger (single‑gene) |
| Coverage | Full gene – all exons & splice sites | Limited to known hotspots |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Diagnostic Sensitivity | >99.9% | ~98% (only known variants) |
Physician Insight & Safety Protocol
“As a Neurologist, I understand the profound anxiety that accompanies a suspected diagnosis of Lowe syndrome. This NGS test provides critical molecular clarity, but results must always be correlated with clinical findings and a thorough family history. Never hesitate to discuss the implications with a clinical geneticist.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠️ Medication Warning: Do not discontinue any prescribed medication without consulting your doctor. This test is for diagnostic information only and does not replace ongoing medical care.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide adequate blood/DNA sample; severe anemia (Hb <7 g/dL) – discuss alternative sample sources with our team.
- Exclusion: Recent allogeneic stem cell transplant or blood transfusion within 4 weeks may interfere with germline genetic analysis.
- Emergency: If you experience prolonged bleeding, large hematoma, or signs of infection at the collection site, seek immediate medical attention.
Frequently Asked Questions & Clinical Guidance
Q: What does the OCRL gene sequencing test detect?
This test identifies all pathogenic variants in the entire OCRL gene, confirming or ruling out Lowe oculocerebrorenal syndrome with 99.9% sensitivity. It captures missense, nonsense, splice-site mutations, and small deletions/insertions through NGS, providing a definitive molecular diagnosis when clinical features suggest Lowe syndrome. The report includes interpretation by DHA-licensed genetic consultants.
يكشف هذا الفحص عن جميع الطفرات الممرضة في جين OCRL لتأكيد أو استبعاد متلازمة لوي بدقة 99.9%.
Q: How is the sample collected for this genetic test?
A certified phlebotomist collects a small blood sample (3‑5 mL) via our hospital-grade home service between 8 AM and 11 PM. We also accept extracted DNA or a dried blood spot on an FTA card. The specimen is immediately placed in a cold‑chain container and transported to our ISO‑accredited laboratory. No special preparation is needed, but a prior genetic counselling session is advised.
يتم سحب عينة دم بسيطة (3-5 مل) عن طريق أخصائي سحب دم معتمد في منزلك، وتُنقل مباشرةً في حاوية مبردة إلى المختبر المعتمد.
Q: What happens if my OCRL gene test result is positive?
A positive result confirms the molecular diagnosis of Lowe syndrome and triggers a multidisciplinary care plan involving neurology, nephrology, and ophthalmology. Our team provides a telephonic post‑test session to explain the findings, discuss inheritance patterns (X‑linked recessive), and facilitate timely referrals. Family cascade testing and genetic counselling are also arranged upon request.
إذا كانت النتيجة إيجابية، يتم تأكيد التشخيص الجزيئي لمتلازمة لوي، وتُنظّم خطة رعاية متعددة التخصصات تشمل طب الأعصاب والكلى والعيون.
This is offered under DHA Facility License No. 9834453 and complies with Federal Decree‑Law No. 41 of 2024 (Art. 87), UAE PDPL (Personal Data Protection Law), and CDS Law 2026 regarding minors.
Laboratory accredited to ISO 9001:2015 (Certificate: INT/EGQ/2509DA/3139). All genetic data are stored and processed in full compliance with UAE healthcare regulations.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians