Test Price
2,800 AED✅ Home Collection Available
OCRL Gene Dent Disease Type 2 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
✅ 99.9% Diagnostic Sensitivity – ISO 9001:2015 Certified Laboratory
✅ Hospital‑Grade Home Collection: ISO‑Certified Cold‑Chain Phlebotomy (8 AM‑11 PM)
✅ VIP Mobile Phlebotomy Service – premium logistics included
✅ Post‑Test Clinical Guidance via Tele‑consultation
✅ Direct Insurance Billing Verification: WhatsApp +971 54 548 8731
Test Overview & Methodology
The OCRL Gene Dent Disease Type 2 Genetic Test is a next‑generation sequencing assay that comprehensively screens for pathogenic variants in the OCRL gene, the definitive cause of X‑linked Dent disease type 2 – a rare renal tubular disorder often misclassified as a neurological condition. In the UAE, this test is performed under strict DHA diagnostic guidelines ensuring precision and mandated genetic counselling.
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) covering all OCRL exons & splice sites | Single‑gene Sanger sequencing |
| Analytical Sensitivity | >99.9% for substitutions & small indels | ~99.0% |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Clinically Relevant Deletion/Duplication Detection | Included (bioinformatic CNV calling) | Not available |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403: “This genetic test identifies the molecular underpinnings of Dent disease type 2 with high analytical sensitivity. The results must be interpreted in the full context of clinical history, renal function, and family pedigree. A mandatory genetic counselling session accompanies every report to ensure accurate understanding of inheritance patterns and recurrence risks.”
Advisory Precautions
🚨 Medication & Treatment Advisory
Do not discontinue any prescribed medication or alter your treatment regimen without explicit consultation with your treating physician. Genetic test results are a diagnostic aid and do not replace professional medical judgment.
Exclusion Criteria & Emergency Red Flags
🚨 Exclusion Criteria & ER Red Flags
- Exclusion: Active severe infection or recent blood transfusion (within 3 weeks) may affect DNA integrity; retest after full recovery.
- Emergency: Sudden onset of severe flank pain, inability to urinate, or high fever with confusion requires immediate emergency care, not an outpatient genetic test.
- Minors: DNA collection from minors mandates documented informed consent from both guardians in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What exactly does the OCRL Gene Dent Disease Type 2 NGS test detect?
Answer: It detects pathogenic single nucleotide variants, small insertions/deletions, and exon‑level copy number changes in the OCRL gene that cause Dent disease type 2, an X‑linked renal tubulopathy characterized by low molecular weight proteinuria, hypercalciuria, and progressive kidney dysfunction.
2. How long does the test take and what sample type is required?
Answer: The test requires a whole blood sample, extracted DNA, or a single blood drop on an FTA card. Results are delivered within 3–4 weeks from sample receipt at the laboratory.
3. Is genetic counselling included and how should I prepare?
Answer: A mandatory pre‑test genetic counselling session is provided to draw a family pedigree, explain X‑linked inheritance patterns, and discuss potential implications. No special physical preparation is needed for the blood draw; however, a list of all current medications should be brought to the counselling session.
4. Can this test be performed during pregnancy or on a child?
Answer: Yes, the test can be performed on individuals of any age including children. For minors, documented informed consent from both guardians is required under UAE medical liability law. Prenatal testing is also available upon request with specialist genetic counselling.
UAE Regulatory & Data Privacy Adherence
This genetic test is performed under the regulatory framework of the Dubai Health Authority (DHA) and complies fully with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring your genetic data is processed lawfully, stored securely, and never shared without explicit consent.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing the secure handling of electronic health records and telemedicine consultations.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – safeguarding patient consent protocols and clinical accountability.
All genetic data is encrypted and accessible only to authorised clinical personnel. Results are communicated via secure channels with mandatory post-test genetic counselling.
Clinical & Logistical Metadata
| Test Name | OCRL Gene Dent Disease Type 2 Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card Blood Spot |
| Methodology Used | Next‑Generation Sequencing (NGS) – Full OCRL gene coverage including all exons and splice sites with bioinformatic CNV calling |
| ICD-10-CM Code | N25.89, N15.1 |
| LOINC Code | 60777-8 |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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