Test Price
2,800 AED✅ Home Collection Available
OAT Gene Gyrate Atrophy of Choroid and Retina Genetic Test in UAE | AED 2800 | 2026 DHA Guidelines
تحليل جين OAT (ضمور المشيمية والشبكية الجيري) وفرط الأورنيثين بالدم في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
الفحص الجيني المتطور لتشخيص ضمور المشيمية والشبكية الجيري الناتج عن طفرة جين OAT، معتمد من هيئة الصحة بدبي وفق معايير 2026 العالمية.
- ضمان الدقة: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection" and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Comprehensive Overview & Diagnostic Precision
The OAT gene NGS test employs Genetic Test can reveal hyperornithinemia-related metabolic fingerprints, guiding ophthalmologists and metabolic specialists toward personalized surveillance and therapy. يستخدم هذا الفحص تقنية التسلسل الجيني المتطور (NGS) لكشف الطفرات المسببة لمرض ضمور المشيمية والشبكية الجيري وفرط الأورنيثين بالدم، مما يضمن تشخيصاً جزيئياً دقيقاً وفق أحدث المعايير الطبية لعام 2026.
| Feature | Our Test – NGS OAT Gene | Closest Alternative |
|---|---|---|
| Methodology | NGS with Sanger confirmation & CNV analysis | Ophthalmological exam + plasma ornithine assay |
| Diagnostic Sensitivity | >99.9% for pathogenic SNVs/indels | ~85% phenotypic suspicion; no genetic confirmation |
| Turnaround Time | 3-4 Weeks | Immediate (clinical) – 72 hours (biochemical) |
| Clinical Utility | Definitive genetic diagnosis, family planning, gene therapy eligibility | Supports clinical diagnosis; cannot identify carriers |
Physician Insight & Safety Protocol
“We understand that living with an inherited retinal disease can feel overwhelming. This genetic test provides clarity, but it is not a standalone verdict—interpretation must always be coupled with a detailed eye examination and plasma ornithine levels. Our goal is to empower you with knowledge to make informed decisions about your vision and your family’s future.”
— Dr. PRABHAKAR REDDY, DHA License No. 61713011
⚠️ Important Medication Warning:
Do not discontinue or modify any prescribed medication, including low-protein diets or pyridoxine supplementation, without prior consultation with your treating ophthalmologist or metabolic physician. Genetic test results are part of a broader clinical picture.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Test not indicated for asymptomatic individuals without family history or clinical signs of gyrate atrophy.
- Red Flag: Sudden loss of vision, acute eye pain, or symptoms of acute glaucoma require immediate emergency ophthalmic evaluation, not elective genetic testing.
- Red Flag: New‑onset neurological symptoms (seizures, developmental regression) should prompt urgent metabolic workup.
Patient FAQ & Clinical Guidance
1. What does the OAT gene test detect, and how does it confirm gyrate atrophy of the choroid and retina?
Snippet: The OAT gene test detects pathogenic variants in the ornithine aminotransferase gene, confirming gyrate atrophy of the choroid and retina with >99% diagnostic accuracy. This molecular analysis identifies single nucleotide changes, small deletions/insertions, and copy number variations that disrupt enzyme function, leading to retinal degeneration. A positive result, combined with clinical findings and elevated plasma ornithine, establishes a definitive diagnosis and informs prognosis and family screening.
س: ما الذي يكشفه تحليل جين OAT وكيف يؤكد تشخيص ضمور المشيمية والشبكية الجيري؟
ج: يكشف الاختبار الطفرات الممرضة في جين OAT، ويؤكد المرض بدقة تتجاوز 99%، ويحدد أنماط الوراثة ويساعد في تنظيم الأسرة.
2. How should I prepare for the test, and what does the pre‑test genetic counselling involve?
Snippet: Pre‑test preparation includes providing a detailed clinical history and attending a genetic counselling session to construct a pedigree, ensuring informed consent and accurate risk assessment for family members. The counsellor will explain autosomal recessive inheritance, possible results (pathogenic, variant of uncertain significance, benign), and implications for siblings and future children. No fasting or medication changes are required; sample collection can be performed on whole blood, extracted DNA, or a single drop of blood on an FTA card.
س: كيف أستعد للفحص وما الذي تتضمنه الجلسة الاستشارية الوراثية قبل الاختبار؟
ج: يلزم تقديم تاريخ طبي دقيق ورسم شجرة العائلة الوراثية خلال جلسة استشارة وراثية لضمان التقييم الصحيح للمخاطر والموافقة المستنيرة.
3. Can this test determine if I am a carrier for gyrate atrophy, and how does it impact family planning?
Snippet: The OAT gene NGS test can reliably identify heterozygous carriers who show no symptoms but can pass the condition to offspring, making it an essential tool for reproductive risk assessment and family planning in the UAE. When both partners are carriers, each pregnancy has a 25% chance of an affected child; genetic counselling post‑ can discuss options such as preimplantation genetic diagnosis or prenatal testing. Results are reported according to DHA 2026 guidelines, with full confidentiality under UAE PDPL.
س: هل يمكن للفحص تحديد ما إذا كنت حاملاً للمرض وكيف يؤثر ذلك على تنظيم الأسرة؟
ج: يكشف الفحص عن حاملي الصفة الوراثية بصورة موثوقة، مما يساعد الأزواج على اتخاذ قرارات مستنيرة حول الإنجاب واختيار تقنيات المساعدة على الإنجاب حسب القوانين الإماراتية.
UAE Compliance: This service adheres to Federal Decree‑Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), and UAE PDPL (Federal Decree‑Law No. 45 of 2021). Facility License No. 9834453. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians