Test Price
2,800 AED✅ Home Collection Available
NEFH Gene Amyotrophic Lateral Sclerosis Susceptibility Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Diagnostic sensitivity >99.9% via ISO-certified Next Generation Sequencing (NGS) laboratory.
- VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Post-test telephonic genetic counseling by a Consultant Medical Geneticist for result interpretation.
- Insurance verification via WhatsApp at +971 54 548 8731; direct billing supported for many UAE insurers.
Test Overview & Methodology
This advanced genetic test analyzes the NEFH gene for pathogenic variants associated with susceptibility to amyotrophic lateral sclerosis (ALS). Early identification of at-risk individuals enables proactive neurological surveillance, lifestyle adjustments, and potential enrollment in clinical trials. The test employs Next Generation Sequencing (NGS) to achieve comprehensive coverage of the NEFH coding regions and splice sites.
| Feature | Our Test (NEFH NGS) | Closest Alternative (Single-Gene Sanger Sequencing) |
|---|---|---|
| Precision | >99.9% analytical sensitivity; comprehensive coverage | ~95% sensitivity; limited to targeted regions only |
| Method | Next Generation Sequencing (NGS) | Sanger Sequencing |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403: “As a consultant medical geneticist, I often counsel families concerned about ALS. This test identifies genetic susceptibility variants in the NEFH gene, which requires careful correlation with clinical findings and family history. It is not a diagnostic test for ALS. Please continue any prescribed treatments and consult your neurologist before making changes.”
Medication & Clinical Advisory
Do not discontinue prescribed medication without consulting your doctor. Genetic results should be discussed with a specialist for appropriate clinical interpretation and management.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Minors without parental/legal guardian consent (per UAE medical liability regulations); patients unable to provide informed consent.
- Exclusion: Acute psychiatric instability or severe cognitive impairment that prevents understanding of test implications.
- ER Red Flag: If you experience sudden limb weakness, difficulty breathing, or choking, seek emergency medical care immediately.
- ER Red Flag: Progressive bulbar symptoms (slurred speech, swallowing difficulty) require urgent neurological evaluation.
Patient FAQ & Clinical Guidance
1. How does the NEFH gene test help in ALS risk assessment?
This test detects pathogenic NEFH variants associated with familial ALS, providing critical risk stratification for patients and families. Neurologists and genetic counsellors use this data to recommend surveillance, lifestyle modifications, and possible clinical trial eligibility.
2. What sample is required and how is it collected?
A peripheral whole blood sample, extracted DNA, or a single blood drop on an FTA card is accepted. Collection is supported via our VIP Mobile Phlebotomy service with temperature-controlled cold-chain preservation, available daily from 8 AM to 11 PM.
3. Is this test covered by insurance in the UAE?
We provide direct billing verification through WhatsApp at +971 54 548 8731. Many UAE insurers cover genetic testing for neurological disorders when medically justified by a specialist.
UAE Regulatory & Data Privacy Adherence
This test is conducted in full compliance with UAE federal data protection and health information laws. All personal data is processed under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is a DHA-licensed facility (License No. 1143) operating under the regulatory oversight of the Dubai Health Authority.
Clinical & Logistical Metadata
| Test Name | NEFH Gene Amyotrophic Lateral Sclerosis Susceptibility Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood, Extracted DNA, or FTA Card (Dried Blood Spot) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM–11 PM) |
| Methodology Used | Next Generation Sequencing (NGS) |
| ICD-10-CM Code | Z15.89 |
| LOINC Code | 21623-1 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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