Test Price
2,800 AED✅ Home Collection Available
NDUFS2 Gene – Mitochondrial Complex I Deficiency Genetic Test in Dubai
Executive Summary & Core Metrics
- 99.9% Diagnostic Accuracy via ISO 9001:2015 certified laboratory (Cert: INT/EGQ/2509DA/3139).
- VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – Available daily from 8 AM to 11 PM.
- Post-Test Clinical Guidance – Teleconsultation with a Consultant Medical Geneticist for result interpretation.
- Insurance Verification – WhatsApp +971 54 548 8731.
- Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Test Overview & Methodology
This next-generation sequencing (NGS) assay for the NDUFS2 gene is the gold standard for diagnosing mitochondrial complex I deficiency, a rare hereditary disorder causing progressive neurological deterioration. The test detects single nucleotide variants, small insertions/deletions, and copy number variations with 99.9% analytical sensitivity, providing definitive molecular confirmation.
| Feature | Our Test – NDUFS2 NGS | Standard Mitochondrial Panel (Limited Genes) |
|---|---|---|
| Methodology | NGS (Targeted Capture + Illumina Platform) | Sanger Sequencing or Small Panel qPCR |
| Analytical Precision | 99.9%–100% for SNVs/Indels & CNVs | May miss deep intronic/regulatory variants |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks (often batching delays) |
Physician Insight & Safety Protocols
“As a consultant in medical genetics, I recognise the profound uncertainty that surrounds a suspected mitochondrial disorder. This NGS test offers a decisive diagnostic answer, but it must be interpreted alongside the full clinical picture including neurological examination, metabolic studies, and family history. A negative result does not exclude other mitochondrial genes or complex deficiencies; close follow-up with your treating neurologist is essential.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Advisory & Safety Protocols
Do not discontinue any prescribed medication or supplement without explicit instruction from your physician. Altering anti‑epileptics, metabolic supplements, or other neurologically active drugs can precipitate severe decompensation.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide a venous blood sample or FTA card finger‑prick sample. Minors must be accompanied by a legal guardian.
- Exclusion: Ongoing chemotherapy that significantly reduces leukocyte count may require postponement.
- Emergency Warning: If you or your child develop acute worsening of muscle weakness, sudden breathing difficulty, seizures, altered consciousness, or stroke‑like episodes, call 998 for ambulance and notify the emergency physician of a suspected mitochondrial disorder.
Patient FAQ & Clinical Guidance
1. What is the NDUFS2 NGS test?
This next-generation sequencing test accurately detects harmful NDUFS2 gene mutations to confirm mitochondrial complex I deficiency diagnosis. It screens for single nucleotide variants, insertions/deletions, and copy number changes that disrupt energy production in cells, causing progressive neurological disease.
2. How is the sample collected?
Our VIP home collection service uses a painless venipuncture (or finger‑prick for FTA cards) performed by a DHA‑licensed phlebotomist. Whole blood (EDTA) or a single dried blood spot can be used, transported under strict cold‑chain conditions. The service is available daily from 8 AM to 11 PM.
3. When will I receive the results?
The report is issued within 3 to 4 weeks from sample receipt, and includes a full clinical interpretation by a molecular geneticist. You will be notified by SMS and email, with the option for a post‑test teleconsultation to discuss findings.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License No. 1143, located at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. All genetic testing is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient data is encrypted and handled with strict confidentiality. For any data protection inquiries, contact our Data Protection Officer at www.dnalabsuae.com.
Clinical & Logistical Metadata
| Test Name | NDUFS2 Gene – Mitochondrial Complex I Deficiency Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) – Targeted Capture on Illumina Platform |
| ICD-10-CM Code | E88.49 |
| LOINC Code | 81328-7 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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