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Test Price

2,800 AED

✅ Home Collection Available

MT‑TV Gene Sequencing (NGS) for Ataxia, Progressive Seizures, Mental Deterioration & Hearing Loss in UAE | 2,800 AED | DHA-Licensed

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑accredited NGS processing, covering the full MT‑TV gene and copy number variations.

Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (available daily 8 AM – 11 PM) for your convenience.

Clinical Guidance: Complimentary telephonic post‑test consultation with a DHA‑licensed consultant medical geneticist to interpret results.

Insurance: Direct billing verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The MT‑TV gene test analyses the mitochondrial tRNA‑valine gene for mutations linked to progressive neurological symptoms including ataxia, refractory seizures, cognitive decline, and sensorineural hearing loss. Our next‑generation sequencing (NGS) platform delivers >1,000× coverage with >99.9% analytic sensitivity, detecting pathogenic variants, mosaic mutations, and copy number alterations. Results are correlated with clinical presentation and family history by our consultant medical geneticist.

Feature Our Test Closest Alternative
Precision NGS with >1,000× coverage, >99.9% analytic sensitivity Sanger sequencing (limited to single hotspots)
Methodology Whole MT‑TV gene screening + copy number variation Targeted mutation panel only
Turnaround 14–21 working days (ISO cold chain) 28 days+

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403) advises: “MT‑TV mutations present a wide phenotypic spectrum; a positive result must be interpreted alongside clinical findings, metabolic workup, and family pedigree. Negative results do not exclude other mitochondrial or nuclear genes. Always correlate genetic data with neurological evaluation and mitochondrial function tests.”

Important Medication Advisory

⚠️ Medication Notice

Do not discontinue prescribed anticonvulsants, mitochondrial supplements, or any other medication without consulting your treating physician. Genetic results are not a substitute for ongoing medical management.

Exclusion Criteria & Emergency Red Flags

  • Active uncontrolled seizures or status epilepticus — seek immediate emergency care.
  • Known coagulopathy or recent anticoagulant use precluding safe blood draw.
  • Inability to provide informed consent without a legal guardian (mandatory for minors under UAE Federal Law).
  • Missing pre‑test genetic counselling session with a pedigree chart — results may become clinically uninterpretable.
  • Severe psychiatric instability that compromises the counselling process.

Patient FAQ & Clinical Guidance

1. What is the MT‑TV gene test for ataxia, seizures, and hearing loss?

This genetic test analyzes the mitochondrial MT‑TV gene to identify pathogenic variants responsible for progressive neurological symptoms including ataxia, seizures, mental deterioration, and sensorineural hearing loss. It enables accurate diagnosis, prognosis, and family risk stratification.

2. How is the sample collected and what is the turnaround time?

A trained phlebotomist visits your home under our VIP Mobile Phlebotomy service (8 AM – 11 PM) to collect a peripheral whole blood sample. The specimen is transported via temperature‑controlled cold chain to our ISO‑accredited laboratory. Results are delivered within 14–21 working days, followed by a telephonic genetic counselling session.

3. Is this test covered by UAE health insurance and how do I verify?

Many UAE insurers reimburse diagnostic genetic testing when ordered by a DHA‑licensed neurologist or geneticist. Send a copy of your insurance card via WhatsApp to +971 54 548 8731 for direct billing verification within 2 hours.

4. What should I do if I experience severe symptoms while awaiting results?

Seek immediate emergency care. This test is not intended for acute management; it is a diagnostic tool for chronic progressive conditions. Never delay emergency treatment.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance: This genetic test is performed in full accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent processes follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).

Clinical & Logistical Metadata

Test Name MT‑TV Gene Sequencing (NGS) for Ataxia, Progressive Seizures, Mental Deterioration & Hearing Loss
Price (AED) 2,800 AED
Turnaround Time 14–21 working days
Sample Type / Matrix Peripheral whole blood (VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection)
Methodology Used Next‑Generation Sequencing (NGS) – Whole gene screen + CNV analysis
ICD-10-CM Code G31.9
LOINC Code 94306-8
DHA Facility License & Laboratory Address DHA Facility License Number: 1143
Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
Corporate Lab: DNA Labs UAE

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