Test Price
2,800 AED✅ Home Collection Available
MTRR Gene (Homocystinuria‑Megaloblastic Anemia, cblE Type) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary
This advanced NGS‑based test interrogates the MTRR gene to confirm or exclude homocystinuria‑megaloblastic anemia type cblE. It delivers 99.9% diagnostic sensitivity, ISO‑accredited processing, and VIP mobile phlebotomy with temperature‑controlled cold‑chain home collection (8 AM–11 PM). Post‑test telephonic clinical guidance is included.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (daily 8 AM–11 PM).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This genetic test provides definitive molecular diagnosis of cblE‑type homocystinuria via next‑generation sequencing (NGS) of the MTRR gene. It detects pathogenic single‑nucleotide variants, insertions, deletions, and duplications with >99.9% sensitivity. The table below contrasts this gold‑standard approach with traditional biochemical assays.
| Feature | Our MTRR NGS Test | Standard Biochemical/Enzymatic Assay |
|---|---|---|
| Diagnostic Precision | >99.9% sensitivity for pathogenic variants | Indirect; may miss rare or private variants |
| Methodology | NGS (Next Generation Sequencing) – full gene analysis | Plasma homocysteine, methylmalonic acid, complementation assays |
| Turnaround Time | 3–4 Weeks | 1–2 Weeks (but often requires follow‑up genetic confirmation) |
Physician Insight & Safety Protocols
Dr. Lina Osama Zaki Quteineh – Consultant Medical Genetics
“This MTRR NGS test is the definitive tool for diagnosing cblE‑type homocystinuria. A positive result confirms an actionable condition that can be managed with vitamin B12 and betaine, but it must always be interpreted in the context of full clinical and biochemical evaluation. Do not alter any current therapy without consulting your genetic specialist.”
Advisory & Safety
⚠️ Medication Warning
Do not discontinue prescribed medication without consulting your doctor. This test provides diagnostic information only; treatment decisions must be made by a qualified physician.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Not indicated for individuals without a clinical suspicion or family history of homocystinuria‑megaloblastic anemia; cannot replace routine vitamin B12 or folate monitoring; not suitable for patients unable to provide a blood sample.
- Emergency Red Flags: If you experience sudden vision loss, stroke‑like symptoms (slurred speech, limb weakness), or unexplained clots, seek emergency care immediately regardless of pending test results.
Patient FAQ & Clinical Guidance
1. What exactly does this MTRR gene test detect?
This NGS panel identifies pathogenic DNA variants in the MTRR gene that cause homocystinuria‑megaloblastic anemia, cblE type, with near‑perfect diagnostic sensitivity.
2. How is the sample collected, and what is the turnaround time?
We offer VIP mobile phlebotomy and temperature‑controlled cold‑chain home collection (daily 8 AM–11 PM) for a standard peripheral blood draw. Results are delivered securely within 3 to 4 weeks.
3. Will my insurance cover this test?
We provide direct billing verification via WhatsApp at +971 54 548 8731. Many UAE insurers cover genetic testing for clinically indicated conditions; contact us to verify your plan.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance
This laboratory test is performed under the strict regulatory framework of the Dubai Health Authority (DHA) and complies with:
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring your genetic data is processed lawfully and securely.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology (ICT) in Health Fields – governing the digital handling of health information.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – safeguarding patient consent and clinical safety.
Your sample and results are handled exclusively within DHA‑licensed facilities (License No. 1143) and processed under ISO 9001:2015 quality standards.
Clinical & Logistical Metadata
| Test Name | MTRR Gene (Homocystinuria‑Megaloblastic Anemia, cblE Type) – NGS |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) – FTA Card or EDTA tube |
| Methodology Used | Next Generation Sequencing (NGS) – full gene analysis |
| ICD‑10‑CM Code | E72.19 (Other disorders of homocysteine metabolism) |
| LOINC Code | 81318-0 (MTRR gene mutation analysis in Blood by Molecular genetics method) |
| DHA Facility License & Address | DHA License #1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – Corporate Lab: DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians