Test Price
2,800 AED✅ Home Collection Available
MT‑TK Gene Analysis (MERRF Syndrome) – Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity via ISO 9001:2015 certified NGS workflow with Sanger confirmation.
- Premium Logistics: VIP mobile phlebotomy & temperature‑controlled cold‑chain home collection (daily 8 AM – 11 PM).
- Post‑Test Guidance: Telephone consultation with a genetic counsellor to interpret results and discuss family implications.
- Insurance Verification: Instant check via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This advanced Next‑Generation Sequencing (NGS) test screens the entire MT‑TK mitochondrial gene for pathogenic variants linked to Myoclonic Epilepsy with Ragged Red Fibers (MERRF) syndrome, a multi‑system disorder. The assay provides definitive molecular confirmation when clinical findings are suggestive, and supports family risk assessment and pregnancy planning.
| Feature | Our Test | Closest Alternative (mtDNA hotspot panel) |
|---|---|---|
| Precision | Full gene sequencing + copy number analysis | Limited to common point mutations (m.8344A>G only) |
| Methodology | NGS with Sanger confirmation & bioinformatic pipeline (LC‑MS/MS validated) | Allele‑specific PCR or single‑site sequencing |
| Speed (TAT) | 3 to 4 weeks from sample receipt | 2 to 3 weeks (may miss rare variants) |
Physician Insight & Safety Protocols
“This test is a powerful tool in the diagnostic workup of mitochondrial diseases, but due to heteroplasmy variability across tissues, a negative result does not exclude MERRF. Clinical correlation with neuromuscular and metabolic findings is essential, and results must be interpreted within a multidisciplinary team including geneticists, neurologists, and metabolic specialists.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA ID: 9294403
⚠ Medication Safety Advisory
Do not discontinue any prescribed medication, anti‑epileptics, or supplements without explicit instruction from your treating physician. Abrupt changes may exacerbate metabolic instability in mitochondrial disorders.
Exclusion Criteria & Emergency Red Flags
- Known hypersensitivity to phlebotomy materials or anticoagulants.
- Acute metabolic crisis, status epilepticus, or stroke‑like episode – seek emergency care first.
- Severe coagulopathy or platelet count <20×10⁹/L (relative contraindication).
- Patients under 18 years must have legal guardian consent per UAE Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What conditions does this MT‑TK gene test specifically diagnose?
This clinical‑grade NGS test sequences the entire MT‑TK gene to detect disease‑causing variants associated with MERRF syndrome (Myoclonic Epilepsy with Ragged Red Fibers). It can also identify overlapping phenotypes such as MELAS or Leigh‑like presentations when MT‑TK mutations are found.
2. How should I prepare before sample collection?
Inform your physician and the lab about all current medications and supplements. A 30‑minute genetic counselling session is required to draw a detailed three‑generation pedigree chart. No fasting is necessary. The home phlebotomist will verify your identity and clinical history.
3. What sample types are accepted?
Whole blood (3–5 mL in EDTA), extracted DNA (≥1 µg), or a single drop of blood on an FTA card. VIP mobile phlebotomy is available daily from 8 AM to 11 PM.
4. How long does the test take?
Turnaround time is 3 to 4 weeks from sample receipt at our Dubai Healthcare City laboratory.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly complies with:
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – all genetic data is encrypted and access‑controlled.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – ensuring secure digital handling and telemedicine integration.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – governing clinical consent and safety protocols.
DHA Facility License No. 1143 | Laboratory operated under the corporate branding of DNA Labs UAE.
Clinical & Logistical Metadata
| Test Name | MT‑TK Gene Analysis (MERRF Syndrome) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card |
| Methodology Used | Next‑Generation Sequencing (NGS) with Sanger confirmation and bioinformatic pipeline |
| ICD‑10‑CM Code | E88.49 (Other mitochondrial metabolism disorders) |
| LOINC Code | 58274-6 (MT‑TK gene analysis) |
| DHA Facility License & Laboratory Address | Licence No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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